Albuterol Inhalation Solution

Lub npe dav: Albuterol sulfate
Dosage form: inhalation daws
Chav kawm tshuaj: Cov tshuaj adrenergic bronchodilators

Ntawm nplooj ntawv no
Nthuav

Albuterol Inhalation Solution Description

Albuterol sulfate inhalation tov yog ib qho kev xaiv betaob-adrenergic bronchodilator (saibCLINICAL PHARMACOLOGYntu hauv qab no). Albuterol sulfate, daim ntawv racemic ntawm albuterol, muaj cov tshuaj npe αib[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-α, α'diol sulfate (2: 1) (ntsev), thiab cov qauv hauv qab no:




Albuterol sulfate muaj qhov hnyav molecular ntawm 576.71 thiab cov mis molecular (C13Hnees nkaum ibTSIS TAU3)ob• HobYOG4. Albuterol sulfate yog cov hmoov dawb los yog siv tau dawb, dawb soluble hauv dej thiab me ntsis soluble hauv cawv.

Lub Koom Haum Ntiaj Teb Kev Noj Qab Haus Huv tau pom zoo lub npe rau albuterol puag yog salbutamol.

Albuterol sulfate inhalation daws 0.083% yuav tsum tsis txhob dilution ua ntej kev tswj hwm.

Txhua mL ntawm albuterol sulfate inhalation tov (0.083%) muaj 0.83 mg ntawm albuterol (raws li 1 mg ntawm albuterol sulfate USP) nyob rau hauv ib qho isotonic, sterile, aqueous tov uas muaj sodium chloride, edetate disodium thiab sodium citrate; hydrochloric acid yog siv los kho cov pH ntawm 3 thiab 5. Albuterol sulfate inhalation tov (0.083%) tsis muaj sulfiting agents.

Albuterol sulfate inhalation tov yog ib qho ntshiab, tsis muaj xim.

Albuterol Inhalation Solution - Chaw Kho Mob Pharmacology

Lub luag haujlwm tseem ceeb ntawm cov tshuaj beta-adrenergic yog txhawb nqa adenyl cyclase, lub enzyme uas catalyzes tsim ntawm cyclic-3',5'-adenosine monophosphate (cyclic AMP) los ntawm adenosine triphosphate (ATP). Lub cyclic AMP yog li tsim kho cov lus teb ntawm tes.Hauv vitrokev kawm thiabnyobCov kev tshawb fawb kws tshuaj tau pom tias albuterol muaj cov txiaj ntsig zoo rau betaob-adrenergic receptors piv nrog isoproterenol. Thaum nws tau lees paub tias betaob-adrenergic receptors yog cov receptors tseem ceeb hauv bronchial du nqaij, 10% mus rau 50% ntawm beta-receptors hauv tib neeg lub siab tuaj yeem yog beta.ob- receptors. Txawm li cas los xij, kev ua haujlwm meej ntawm cov receptors no tseem tsis tau tsim. Albuterol tau pom nyob rau hauv feem ntau tswj kev sim tshuaj kom muaj kev cuam tshuam ntau dua ntawm cov kab mob ua pa hauv daim ntawv ntawm bronchial du leeg so dua li isoproterenol ntawm cov koob tshuaj sib piv thaum tsim cov teebmeem plawv tsawg dua. Cov kev tshawb fawb soj ntsuam thiab lwm yam kev soj ntsuam tau pom tias nqus tau albuterol, zoo li lwm cov tshuaj beta-adrenergic agonist, tuaj yeem ua rau cov hlab plawv tseem ceeb hauv qee cov neeg mob, raws li ntsuas los ntawm pulse rate, ntshav siab, cov tsos mob, thiab / lossis electrocardiographic hloov.

Albuterol ua haujlwm ntev dua li isoproterenol hauv cov neeg mob feem ntau los ntawm txhua txoj hauv kev ntawm kev tswj hwm vim nws tsis yog ib qho substrate rau cov txheej txheem cellular uptake rau catecholamines los yog rau catechol-O-methyl transferase.

Cov kev tshawb fawb hauv cov neeg mob hawb pob tau pom tias tsawg dua 20% ntawm ib koob tshuaj albuterol tau nqus tau tom qab IPPB (kev ua pa tsis sib xws) lossis kev tswj hwm nebulizer; cov nyiaj seem tau rov qab los ntawm nebulizer thiab apparatus thiab cov cua tas sij hawm. Feem ntau ntawm cov koob tshuaj absorbed tau zoo nyob rau hauv cov zis 24 teev tom qab noj tshuaj. Tom qab noj 3 mg ntawm nebulized albuterol, qhov siab tshaj plaws albuterol plasma theem ntawm 0.5 teev yog 2.1 ng / mL (ntau txog 1.4 txog 3.2 ng / mL).

Muaj cov lus teb tseem ceeb ntawm koob tshuaj hauv FEVib(yuav tsum tas sij hawm ntim hauv ib thib ob) thiab qhov siab tshaj plaws ntws. Nws tau raug pom tias tom qab kev tswj hwm qhov ncauj ntawm 4 mg albuterol, kev tshem tawm ib nrab ntawm lub neej yog tsib mus rau rau teev.

amoxicillin 500 mg siv rau

Tsiaj cov kev tshawb fawb qhia tias albuterol tsis dhau cov ntshav-hlwb barrier. Cov kev tshawb fawb tsis ntev los no hauv cov tsiaj txhu (minipigs, nas, thiab dev) tau sau tseg qhov tshwm sim ntawm lub plawv arrhythmias thiab kev tuag tam sim ntawd (nrog cov pov thawj histologic ntawm myocardial necrosis) thaum beta-agonists thiab methylxanthines tau noj ib txhij. Qhov tseem ceeb ntawm cov kev tshawb pom no thaum siv rau tib neeg tam sim no tsis paub.

Hauv kev sim tshuaj ntsuam xyuas, cov neeg mob feem ntau pom qhov pib ntawm kev txhim kho hauv kev ua haujlwm ntawm lub ntsws hauv 5 feeb raws li tau txiav txim los ntawm FEVib. FEVibKev ntsuas kuj tau pom tias qhov kev txhim kho qhov nruab nrab siab tshaj plaws hauv kev ua haujlwm pulmonary feem ntau tshwm sim ntawm kwv yees li 1 teev tom qab nqus tau 2.5 mg ntawm albuterol los ntawm compressor- nebulizer, thiab tseem nyob ze rau lub ncov rau 2 teev. Kev kho mob tseem ceeb hauv kev ua haujlwm ntawm lub ntsws (txhais tias yog kev saib xyuas ntawm 15% lossis ntau dua ntawm FEVibtshaj qhov tseem ceeb) txuas ntxiv rau 3 mus rau 4 teev hauv cov neeg mob feem ntau thiab qee cov neeg mob txuas ntxiv mus txog 6 teev.

Hauv kev tshawb fawb ntau dua, kev ua tau zoo txuas ntxiv tau pom thoob plaws hauv peb lub hlis ntawm kev kho mob hauv qee tus neeg mob.

Tshaj tawm cov ntawv tshaj tawm txog kev sim rau cov menyuam yaus mob hawb pob hnub nyoog 3 xyoos lossis laus dua tau pom tias muaj kev txhim kho tseem ceeb hauv FEViblos yog PEFR li ntawm 2 mus rau 20 feeb tom qab ib koob tshuaj Albuterol Inhalation Solution. Kev nce ntawm 15% lossis ntau dua hauv qhov pib FEVibtau pom nyob rau hauv cov menyuam yaus hnub nyoog 5 txog 11 xyoos txog 6 teev tom qab kev kho mob nrog koob tshuaj 0.10 mg / kg lossis siab dua ntawm Albuterol Inhalation Solution. Ib koob tshuaj 3, 4 lossis 10 mg ua rau muaj kev txhim kho hauv lub hauv paus PER uas tau muab piv rau qhov ntev thiab ntev mus rau 2 mg koob, tab sis cov koob tshuaj saum toj no 3 mg tau cuam tshuam nrog lub plawv dhia ntau dua 10%.

Cov lus qhia thiab kev siv rau Albuterol Inhalation Solution

Albuterol sulfate inhalation tov yog qhia rau kev kho mob ntawm bronchospasm nyob rau hauv cov neeg mob hnub nyoog 2 xyoos thiab laus dua nrog reversible obstructive airway kab mob thiab mob bronchospasm.

Contraindications

Albuterol sulfate inhalation tov yog contraindicated nyob rau hauv cov neeg mob uas muaj keeb kwm ntawm hypersensitivity rau ib yam ntawm nws cov Cheebtsam.

Ceeb toom

Raws li nrog rau lwm cov inhaled beta-adrenergic agonists, albuterol sulfate inhalation tov yuav ua tau paradoxical bronchospasm, uas yuav ua rau lub neej hem. Yog hais tias nws tshwm sim, qhov kev npaj yuav tsum tau txiav tam sim ntawd thiab lwm txoj kev kho mob instituted.

Cov neeg tuag tau raug tshaj tawm nyob rau hauv kev koom tes nrog kev siv ntau dhau ntawm cov tshuaj inhaled sympathomimetic thiab nrog kev siv tshuaj hauv tsev ntawm nebulizers. Yog li ntawd, nws yog ib qho tseem ceeb uas tus kws kho mob qhia tus neeg mob txog qhov xav tau kev ntsuam xyuas ntxiv, yog tias nws mob hawb pob tuaj. Hauv ib tus neeg mob, txhua yam betaob-adrenergic agonist, suav nrog cov tshuaj albuterol rau kev nqus pa, tuaj yeem ua rau mob plawv tseem ceeb.

Cov tshuaj tiv thaiv kev ntxhov siab tam sim tuaj yeem tshwm sim tom qab kev tswj hwm ntawm albuterol raws li pom los ntawm qhov tsis tshua muaj tshwm sim ntawm urticaria, angioedema, tawm pob, bronchospasm, thiab oropharyngeal edema.

Cov kev ceev faj

General

Albuterol, raws li nrog rau tag nrho cov sympathomimetic amines, yuav tsum tau siv nrog ceev faj rau cov neeg mob uas muaj kab mob plawv, tshwj xeeb tshaj yog coronary insufficiency, plawv arrhythmias thiab kub siab, nyob rau hauv cov neeg mob convulsive ntshawv siab, hyperthyroidism los yog ntshav qab zib mellitus thiab nyob rau hauv cov neeg mob uas txawv txawv teb rau sympathometic.

Cov koob tshuaj loj ntawm cov tshuaj albuterol tau tshaj tawm ua rau ua rau mob ntshav qab zib mellitus thiab ketoacidosis ntau ntxiv. Raws li nrog rau lwm cov beta-agonists, nqus tau thiab intravenous albuterol yuav ua rau ib tug tseem ceeb hypokalemia nyob rau hauv ib co neeg mob, tejzaum nws los ntawm intracellular shunting, uas muaj peev xwm ua rau muaj kev phiv plawv. Qhov txo qis feem ntau yog ncua sijhawm, tsis tas yuav tsum tau ntxiv.

Rov ua dua koob tshuaj nrog 0.15 mg / kg ntawm Albuterol Inhalation Solution hauv cov menyuam yaus hnub nyoog 5 txog 17 xyoo uas tau pib normokalemic tau cuam tshuam nrog asymptomatic poob ntawm 20% mus rau 25% hauv cov ntshav cov ntshav.

prednisone ntau npaum rau 60 lb dev

Cov ntaub ntawv rau cov neeg mob

Qhov kev txiav txim ntawm albuterol sulfate inhalation daws yuav kav ntev li ntawm rau teev, thiab yog li ntawd nws yuav tsum tsis txhob siv ntau zaus tshaj li qhov pom zoo. Tsis txhob nce koob lossis ntau zaus ntawm cov tshuaj yam tsis muaj kev sab laj nrog kws kho mob. Yog tias cov tsos mob hnyav dua, kev sab laj kev kho mob yuav tsum tau nrhiav kom sai. Thaum noj tshuaj albuterol sulfate inhalation tov, lwm yam tshuaj tiv thaiv kab mob hawb pob yuav tsum tsis txhob siv tshwj tsis yog tias tau sau tseg.

Cov tshuaj sib xyaw ua ke (lub cev thiab tshuaj), kev ua tau zoo, thiab kev nyab xeeb ntawm Albuterol Inhalation Solution thaum sib xyaw nrog lwm cov tshuaj hauv lub tshuab nqus tsev tsis tau tsim.

Saib cov duab kos'Tus neeg mob cov lus qhia rau kev siv.'

Cov tshuaj sib cuam tshuam

Lwm yam sympathomimetic aerosol bronchodilators lossis epinephrine yuav tsum tsis txhob siv nrog albuterol.

Albuterol yuav tsum tau noj nrog ceev faj heev rau cov neeg mob tau kho nrog monoamine oxidase inhibitors lossis tricyclic anti-depressants, vim tias qhov kev ua ntawm albuterol ntawm cov hlab ntsha tuaj yeem ua rau muaj zog.

Beta-receptor thaiv cov neeg ua haujlwm thiab albuterol inhibit qhov sib txawv.

Carcinogenesis, Mutagenesis, thiab Impairment of Fertility

Albuterol sulfate ua rau muaj kev nce ntxiv ntawm cov koob tshuaj uas cuam tshuam rau qhov tshwm sim ntawm benign leiomyomas ntawm mesovarium hauv kev tshawb fawb 2 xyoo hauv cov nas, ntawm qhov ncauj ntawm 2, 10, thiab 50 mg / kg, sib npaug rau 10, 50 thiab 250 zaug, Feem ntau, qhov siab tshaj plaws koob tshuaj rau ib tug neeg 50 kg. Hauv lwm txoj kev tshawb fawb, cov nyhuv no tau thaiv los ntawm kev sib koom ua ke ntawm propranolol. Qhov cuam tshuam ntawm cov kev tshawb pom no rau tib neeg tsis paub. Kev kawm 18 lub hlis hauv cov nas thiab kev tshawb fawb tas li hauv hamsters qhia tsis muaj pov thawj ntawm qog nqaij hlav. Kev tshawb fawb nrog albuterol qhia tsis muaj pov thawj ntawm mutagenesis. Cov kev tshawb fawb txog kev yug me nyuam hauv cov nas pom tsis muaj pov thawj ntawm qhov tsis muaj fertility.

Kev xeeb tub

Cov teebmeem teratogenic

Cev xeeb tub qeb C

Albuterol tau pom tias yog teratogenic hauv cov nas thaum muab subcutaneously hauv cov koob tshuaj sib raug rau 1.25 npaug ntawm tib neeg koob tshuaj (raws li 50 kg tib neeg). Tsis muaj kev tshawb fawb txaus thiab tswj tau zoo hauv cov poj niam cev xeeb tub. Albuterol yuav tsum tau siv thaum cev xeeb tub nkaus xwb yog tias cov txiaj ntsig muaj peev xwm ua rau muaj kev pheej hmoo rau tus menyuam hauv plab. Kev tshawb fawb txog kev yug me nyuam hauv CD-1 nas nrog albuterol (0.025, 0.25, thiab 2.5 mg / kg subcutaneously, sib xws rau 0.125, 1.25 thiab 12.5 npaug ntawm qhov siab tshaj plaws ntawm tib neeg koob tshuaj, raws li) pom pom kev tsim ntawm cleft palate hauv 1 5 ntawm 11. fetuses ntawm 0.25 mg / kg thiab 10 ntawm 108 (9.3%) fetuses ntawm 2.5 mg / kg. Tsis muaj leej twg tau pom ntawm 0.025 mg / kg. Cleft palate kuj tshwm sim nyob rau hauv 22 ntawm 72 (30.5%) fetuses kho nrog 2.5 mg / kg isoproterenol (zoo tswj). Ib txoj kev tshawb fawb txog kev yug me nyuam hauv Stride Dutch luav qhia cranioschisis nyob rau hauv 7 ntawm 19 (37%) fetuses ntawm 50 mg / kg, sib xws rau 250 npaug ntawm qhov siab tshaj plaws nebulization koob tshuaj rau 50 kg tib neeg.

Thaum lub sij hawm kev lag luam thoob ntiaj teb, ntau yam kev tsis sib haum xeeb ntawm lub cev, suav nrog cleft palate thiab limb defects, tsis tshua muaj tshwm sim hauv cov xeeb ntxwv ntawm cov neeg mob tau kho nrog albuterol. Qee leej niam tau noj ntau yam tshuaj thaum cev xeeb tub. Tsis muaj cov qauv ntawm qhov tsis xws luag tuaj yeem pom, thiab kev sib raug zoo ntawm kev siv albuterol thiab congenital anomalies tsis tau tsim.

Kev Ua Haujlwm thiab Kev Xa Khoom

Qhov ncauj albuterol tau pom tias yuav ncua kev ua haujlwm ua ntej lub sijhawm ua haujlwm hauv qee cov lus ceeb toom. Tam sim no tsis muaj cov kev tshawb fawb tswj tau zoo uas qhia tau tias nws yuav tsum tsis txhob ua haujlwm ua ntej lossis tiv thaiv kev ua haujlwm ntawm lub sijhawm. Yog li ntawd, ceev faj siv cov tshuaj albuterol sulfate inhalation yog yuav tsum tau nyob rau hauv cov neeg mob cev xeeb tub thaum muab rau kev kho mob ntawm bronchospasm thiaj li tsis txhob cuam tshuam nrog uterine contractibility.

Niam laus

Nws tsis paub tias cov tshuaj no puas tawm hauv tib neeg cov kua mis. Vim tias muaj peev xwm ntawm cov qog nqaij hlav pom rau albuterol hauv qee qhov kev tshawb fawb tsiaj, kev txiav txim siab yuav tsum txiav txim siab seb puas yuav tsum tsis tu ncua lossis txiav cov tshuaj, suav nrog qhov tseem ceeb ntawm cov tshuaj rau leej niam.

Kev siv menyuam yaus

Kev nyab xeeb thiab kev ua tau zoo ntawm albuterol sulfate inhalation tov tau tsim rau cov menyuam yaus hnub nyoog 2 xyoos lossis laus dua. Kev siv cov tshuaj albuterol sulfate inhalation daws nyob rau hauv cov hnub nyoog pawg no yog txhawb los ntawm cov pov thawj los ntawm cov kev tshawb fawb txaus thiab tswj tau zoo ntawm albuterol sulfate inhalation tov rau cov neeg laus; qhov tshwm sim ntawm cov kab mob, pathophysiology, thiab cov tshuaj muaj txiaj ntsig hauv cov menyuam yaus thiab cov neeg laus muaj qhov sib xws; thiab luam tawm cov ntawv ceeb toom ntawm kev sim hauv cov neeg mob menyuam yaus hnub nyoog 3 xyoos lossis laus dua. Cov koob tshuaj pom zoo rau cov menyuam yaus yog ua raws li peb qhov kev sib piv koob tshuaj luam tawm ntawm kev ua tau zoo thiab kev nyab xeeb hauv cov menyuam yaus hnub nyoog 5 txog 17 xyoo, thiab ntawm qhov kev nyab xeeb ntawm cov neeg laus thiab cov neeg mob hauv cov menyuam yaus ntawm koob tshuaj sib npaug lossis siab dua li cov koob tshuaj pom zoo. Kev nyab xeeb thiab kev ua tau zoo ntawm albuterol sulfate inhalation daws hauv cov menyuam yaus hnub nyoog qis dua 2 xyoos tsis tau tsim.

Kev Phem Tsis Zoo

Kev sim tshuaj ntsuam xyuas

Cov txiaj ntsig ntawm kev sim tshuaj nrog albuterol sulfate inhalation daws hauv 135 cov neeg mob tau pom cov kev mob tshwm sim hauv qab no uas tau txiav txim siab los yog muaj feem cuam tshuam txog tshuaj:

Central Nervous System:tremors (20%), kiv taub hau (7%), nervousness (4%), mob taub hau (3%), insomnia (1%).

plab hnyuv:xeev siab (4%), dyspepsia (1%).

Pob ntseg, qhov ntswg thiab caj pas:pharyngitis (<1%), nasal congestion (1%).

Mob plawv:tachycardia (1%), ntshav siab (1%).

Ua pa:bronchospasm (8%), hnoos (4%), bronchitis (4%), hawb pob (1%).

Tsis muaj qhov chaw kuaj mob ntsig txog kev kuaj mob txawv txav cuam tshuam nrog kev tswj hwm albuterol sulfate inhalation daws tau txiav txim siab hauv cov kev tshawb fawb no.

Hauv kev sib piv cov kev tsis zoo tshwm sim qhia rau cov neeg mob kho nrog albuterol sulfate inhalation tov nrog cov neeg mob kho nrog isoproterenol thaum lub sij hawm soj ntsuam ntawm peb lub hlis, cov nram qab no mob me me mus rau hnyav, raws li txiav txim los ntawm cov neeg soj ntsuam, tau tshaj tawm. Cov lus no tsis suav nrog cov tshuaj tiv thaiv me me.

*
Qhov kev tshawb pom tsis muaj arrhythmias thiab tsis muaj palpitations tom qab kev tswj hwm albuterol hauv qhov kev tshawb fawb soj ntsuam no yuav tsum tsis txhob raug txhais raws li qhov qhia tias cov teebmeem tsis zoo no tuaj yeem tshwm sim tom qab kev tswj hwm ntawm inhaled albuterol.
Feem ntau ntawm bronchospasm, lo lus no feem ntau yog siv los piav txog exacerbations nyob rau hauv cov kab mob pulmonary.
Qhov feem pua ​​​​ntawm qhov mob nruab nrab mus rau qhov tsis zoo tshwm sim
Cov tshuaj tiv thaiv
Albuterol
N = 65
Isoproterenol
N = 65
Central Nervous System


Ntshai
10.7%
13.8%
Mob taub hau
3.1%
1.5%
Insomnia
3.1%
1.5%
Mob plawv


Ntshav siab
3.1%
3.1%
Arrhythmias
0%
3%
* Palpitation
0%
22%
Ua pa


Bronchospasm
15.4%
18%
hnoos
3.1%
5%
Mob ntsws
1.5%
5%
Hnoos
1.5%
1.5%
Sputum nce
1.5%
1.5%
Ua tsis taus pa
1.5%
1.5%
plab hnyuv


Ntshai
3.1%
0%
Dyspepsia
1.5%
0%
Txheej txheem


Malise
1.5%
0%


Postmarketing Experience

alpha lipoic acid kev sib tshuam

Cov neeg mob ntawm urticaria, angioedema, tawm pob, bronchospasm, hoarseness, oropharyngeal edema, arrhythmias (xws li atrial fibrillations, supraventricular tachycardia, extrasystoles) thiab metabolic acidosis tau qhia tom qab siv cov tshuaj albuterol sulfate inhalation. Vim tias cov tshuaj tiv thaiv no tau lees paub los ntawm cov pej xeem tsis paub meej qhov loj, nws tsis yog ib txwm ua tau kom ntseeg tau tias lawv cov zaus los yog tsim kom muaj kev sib raug zoo rau kev siv tshuaj.

Kev noj ntau dhau

Kev tshwm sim ntawm kev noj ntau dhau tuaj yeem suav nrog qaug dab peg, mob anginal, kub siab, hypokalemia, tachycardia nrog tus nqi txog li 200 tus neeg ntaus / min, thiab exaggeration ntawm cov tshuaj pharmacological tau teev tseg hauvTXOJ CAI TSHIAB. Hauv cov xwm txheej sib cais hauv cov menyuam yaus hnub nyoog 2 txog 12 xyoos, tachycardia nrog tus nqi> 200 neeg ntaus / min tau pom.

Qhov ncauj LDtsib caugHauv cov nas thiab nas yog ntau dua 2,000 mg / kg. Inhalational LDtsib caugtsis tuaj yeem txiav txim siab.

Muaj cov pov thawj tsis txaus los txiav txim siab seb kev lim ntshav puas muaj txiaj ntsig rau kev noj ntau dhau ntawm Albuterol Inhalation Solution.

Albuterol Inhalation Solution Dosage and Administration

Cov neeg laus thiab menyuam yaus hnub nyoog 2 txog 12 xyoos

Cov koob tshuaj ib txwm muaj rau cov neeg laus thiab cov menyuam yaus uas hnyav 15 kg yog 2.5 mg ntawm albuterol (ib lub vial) tau muab peb mus rau plaub zaug hauv ib hnub los ntawm nebulization. Cov menyuam hnyav<15 kg who require <2.5 mg/dose (i.e., less than a full vial) should use Albuterol Inhalation Solution, 0.5% instead of Albuterol Inhalation Solution, 0.083%. More frequent administration or higher doses are not recommended. To administer 2.5 mg of albuterol, administer the entire contents of one sterile unit dose vial (3 mL of 0.083% inhalation solution) by nebulization. The flow rate is regulated to suit the particular nebulizer so that Albuterol Inhalation Solution will be delivered over approximately 5 to 15 minutes.

Kev siv cov tshuaj albuterol sulfate inhalation daws tuaj yeem txuas ntxiv raws li kev kho mob qhia los tswj kev rov tshwm sim ntawm bronchospasm. Lub sijhawm no cov neeg mob feem ntau tau txais txiaj ntsig zoo los ntawm kev siv cov tshuaj inhalation tsis tu ncua.

Yog tias qhov kev siv tshuaj ntau npaum li cas yav dhau los ua tsis tau qhov kev pab cuam li niaj zaus, cov lus qhia kho mob yuav tsum tau nrhiav tam sim ntawd, vim qhov no feem ntau yog ib qho kev tshwm sim ntawm kev mob hawb pob hnyav heev uas yuav tsum tau rov ntsuam xyuas kev kho mob.

Yuav ua li cas yog Albuterol Inhalation Solution Supplied

Unit-dose yas vial uas muaj Albuterol Sulfate Inhalation Solution 0.083%, 2.5 mg / 3 mL * (* potency expressed as albuterol). Sib npaug rau 0.5 mL albuterol (raws li sulfate) 0.5% (2.5 mg albuterol) diluted rau 3 mL. Muab nyob rau hauv cartons raws li teev hauv qab no.

NDC 47335-703-49 carton of 25 vials (5 vials per foil pouch)

NDC 47335-703-52 carton of 30 vials (5 vials per foil pouch)

NDC 47335-703-54 carton of 60 vials (5 vials per foil pouch)

Cia

amoxicillin koob tshuaj rau mob hauv siab

Tiv thaiv los ntawm lub teeb. Khaws rau hauv lub hnab kom txog thaum siv. Khaws ntawm 20 ° txog 25 ° C (68 ° txog 77 ° F); Kev mus ncig ua si tso cai ntawm 15 ° thiab 30 ° C (59 ° thiab 86 ° F) [saib USP Controlled Room Temperature].

Tus neeg mob cov lus qhia rau kev siv

Albuterol (al-BUE-ter-ol) Sulfate Inhalation daws 0.083% *

(* Lub zog qhia raws li albuterol)

Faj seeb: Qhov no yog ib koob tshuaj vial. Tsis tas yuav dilution.

Nyeem cov lus qhia ua kom zoo ua ntej siv.

1. Tshem tawm lub vial ntawm lub hnab ntawv ci.

2. Twist lub hau tag nrho tawm ntawm lub vial thiab nyem cov ntsiab lus mus rau hauv lub tank nebulizer (Daim duab 1).

3. Txuas lub tshuab nqus dej rau hauv lub qhov ncauj lossis lub ntsej muag lub ntsej muag (Daim duab 2).

4. Txuas lub nebulizer rau lub compressor.

5. Zaum nyob rau hauv ib tug xis, upright txoj hauj lwm; Muab lub qhov ncauj tso rau hauv koj lub qhov ncauj (Daim duab 3) (los yog muab lub ntsej muag lub ntsej muag); thiab qhib lub compressor.

6.Ua pa li calmly, sib sib zog nqus thiab sib npaugraws li qhov ua tau kom txog thaum tsis muaj huab cua ntxiv nyob rau hauv nebulizer chamber (kwv yees li 5 mus rau 15 feeb). Lub sijhawm no, kev kho mob tiav lawm.

7. Ntxuav lub nebulizer (saib cov chaw tsim khoom cov lus qhia).

Nco tseg: Tsuas yog siv raws li koj tus kws kho mob qhia. Kev noj tshuaj ntau zaus lossis ntau dua tsis pom zoo.

Khaws Albuterol Sulfate Inhalation Solution 0.083% ntawm 20 ° txog 25 ° C (68 ° txog 77 ° F); Excursions tso cai ntawm 15 ° txog 30 ° C (59 ° txog 86 ° F). Khaws rau hauv lub hnab kom txog thaum siv.

Cov lus qhia ntxiv: ______________________

Muab faib los ntawm:
Sun Pharmaceutical Industries, Inc.
Cranbury, NJ 08512

Tsim los ntawm:
Sun Pharmaceutical Medicaretxwv
Baska Ujeti Txoj Kev, Ujeti
Halol-389350, Gujarat, Is Nrias teb

PIB 0032

ISS. 06/2021

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL - Carton

NWS 47335-703-54
Albuterol Sulfate Inhalation Solution, 0.083% *
2.5 mg * 3 mL
* Lub zog qhia tau tias yog albuterol
Rau Inhalation nkaus xwb
Tsis yog txhaj tshuaj
Sib npaug rau 0.5 mL Albuterol Sulfate 0.5% * diluted rau 3 mL ib txwm saline
Rx xwb
60 X 3 mL Sterile Unit-Dose Vials
(5 Unit-Dose Vials rau ib lub hnab, 12 hnab rau ib lub thawv)
TSEV KAWM NTAWV PHARMACIST: Thov xa nrog tus neeg mob cov lus qhia rau kev siv cais.


ALBUTEROL SULFATE
albuterol sulfate daws
Cov ntaub ntawv khoom
Yam khoom HUMAN PRESCRIPTION DRUG LABEL Yam khoom Code (Source) NDC: 47335-703
Txoj kev tswj hwm Ua pa (INHALATION) DEA Teem caij
Cov khoom xyaw nquag / Active Moiety
Cov khoom xyaw npe Lub hauv paus muaj zog Lub zog
ALBUTEROL SULFATE (ALBUTEROL) ALBUTEROL 0.83 mg 1 mL
Cov khoom xyaw uas tsis muaj zog
Cov khoom xyaw npe Lub zog
SODIUM chloride
EDATE DISODIUM
SODIUM CITRATE, UNSPECIFIED FORM
HYDROCHLORIC ACID
Dej
Ntim
# Yam khoom Code Pob piav qhia
ib NDC: 47335-703-49 5 POUCH hauv 1 CARTON
ib 5 VIAL hauv 1 POUCH
ib 3ml hauv 1 VIAL
ob NDC: 47335-703-52 6 POUCH hauv 1 CARTON
ob 5 VIAL hauv 1 POUCH
ob 3ml hauv 1 VIAL
3 NDC: 47335-703-54 12 POUCH hauv 1 CARTON
3 5 VIAL hauv 1 POUCH
3 3ml hauv 1 VIAL
Cov ntaub ntawv lag luam
Kev lag luam qeb Daim ntawv thov Number los yog Monograph Citation Hnub pib ua lag luam Hnub Kawg Ua Lag Luam
KOJ TIAB SA 207857 11/06/2021
Labeler -Sun Pharmaceutical Industries, Inc. (146974886)
Kev tsim kho
Lub npe Chaw nyob ID/FEI Kev ua haujlwm
Sun Pharmaceutical Medicare Limited 725420835 ib SAIB XYUAS (47335-703), MANUFACTURE (47335-703)
Sun Pharmaceutical Industries, Inc.