Clavamox Drops (Canada)

Nplooj ntawv no muaj cov ntaub ntawv hais txog Clavamox Drops rau kev siv kws kho tsiaj .
Cov ntaub ntawv muab feem ntau suav nrog cov hauv qab no:
  • Clavamox Drops Indications
  • Lus ceeb toom thiab ceeb toom rau Clavamox Drops
  • Cov lus qhia thiab ntau npaum li cas rau Clavamox Drops

Clavamox Drops

Txoj kev kho no siv rau cov hom hauv qab no:
Company: Zoetis

Tso tseg

amoxicillin thiab clavulanate potassium rau qhov ncauj tshem tawm USP



Veterinary siv nkaus xwb



Ib 02027879

Kev piav qhia

Clavamox yog ib qho tshuaj noj hauv qhov ncauj uas muaj cov tshuaj tua kab mob broad-spectrum amoxicillin trihydrate thiab β-lactamase inhibitor clavulanate potassium (cov poov tshuaj ntsev ntawm clavulanic acid). Txhua lub raj mis uas tsis tau hloov kho muaj 750 mg ntawm amoxicillin USP thiab 187.5 mg ntawm clavulanic acid (raws li clavulanate potassium, diluted Ph.Eur.).



TSEEM CEEB: Clavamox yog ruaj khov nyob rau hauv lub xub ntiag ntawm gastric acid thiab tsis cuam tshuam los ntawm gastric los yog hnyuv ntsiab lus. Ob lub ntsiab lus yog absorbed sai heev uas ua rau amoxicillin thiab clavulanic acid concentrations nyob rau hauv cov ntshav, zis thiab cov ntaub so ntswg zoo ib yam li cov uas tsim thaum ib leeg yog siv.

Amoxicillin thiab clavulanic acid diffuse nkag mus rau hauv feem ntau ntawm lub cev cov ntaub so ntswg thiab cov kua dej, tshwj tsis yog lub hlwb thiab tus txha caj qaum, uas amoxicillin nkag mus txaus thaum meninges mob. Feem ntau ntawm amoxicillin raug tshem tawm tsis hloov pauv hauv cov zis. Clavulanic acid nkag mus rau hauv cov kua dej txha caj qaum tsis paub txog lub sijhawm no. Kwv yees li 15% ntawm cov koob tshuaj clavulanic acid tau tawm hauv cov zis hauv thawj rau 6 teev.

Clavamox muab cov khoom tshwj xeeb ntawm cov tshuaj tua kab mob thiab β-lactamase inhibitor kom txuas tau cov kab mob tua kab mob ntawm amoxicillin kom muaj xws li β-lactamase nrog rau cov kab mob uas tsis yog-β-lactamase.



MICROBIOLOGY: Amoxicillin yog bactericidal nyob rau hauv kev ua thiab ua los ntawm inhibition ntawm biosynthesis ntawm cell phab ntsa mucopeptide ntawm susceptible microorganisms. Qhov kev txiav txim ntawm clavulanic acid txuas ntxiv cov tshuaj tua kab mob ntawm amoxicillin kom muaj cov kab mob tiv thaiv amoxicillin thiab lwm yam tshuaj tua kab mob β-lactam. Amoxicillin / clavulanate tau pom tias muaj ntau yam kev ua ub no uas ua rau β-lactamase-ua hom ntawm ob qho tib si gram-positive thiab gram-negative aerobes, facultative anaerobes, thiab obligate anaerobes. Ntau hom kab mob hauv qab no, suav nrog β-lactamase tsim cov kab mob cais tawm los ntawm cov kws kho tsiaj, tau pom tias muaj kev cuam tshuam rau amoxicillin / clavulanate. hauv vitro tab sis qhov tseem ceeb ntawm kev kho mob ntawm cov dej num no tsis tau pom zoo rau qee yam ntawm cov kab mob hauv cov tsiaj no:

Cov kab mob aerobic, suav nrog Staphylococcus aureus ib, β-lactamase-ua Staphylococcus aureus ib(penicillin resistant), Staphylococcus ua spp.ib, Staphylococcus epidermidis , Staphylococcus intermediaus , Streptococcus faecalis , Streptococcus ua spp.ib, Corynebacterium pyogenes , Corynebacterium spp., Erysipelothrix rhusiapathiae , Bordetella bronchiseptica , Escherichia coli ib, Proteus mirabilis , Proteus spp., Enterobacter spp., Klebsiella pneumoniae , Salmonella Dublin , Salmonella typhimurium , Pasteurella multocida , Pasteurella hemolytica , Pasteurella ua spp.ib

ibQhov susceptibility ntawm cov kab mob microorganisms kuj tau pom nyob rau hauv nyob kev kawm.

Cov kev tshawb fawb tau pom tias ob qho tib si aerobic thiab anaerobic flora yog cais los ntawm gingival kab lis kev cai ntawm dev nrog cov ntaub ntawv pov thawj ntawm cov kab mob periodontal. Ob leeg gram-positive thiab gram-negative aerobic thiab anaerobic subgingival isolates qhia rhiab heev rau amoxicillin / clavulanic acid thaum kuaj tshuaj tiv thaiv kab mob.

SUSCEPTIBILITY TEST: Txoj kev pom zoo kom muaj nuj nqis disc susceptibility (FEDERAL REGISTER 37:20507-29; Bauer AW, Kirby WMM, Sherris JC, thiab al: Tshuaj tua kab mob susceptibility test los ntawm standardized single disc method. Am J Clin Path 45: 493, 1966) siv 30 µg Augmentin discs rau kwv yees cov kab mob cuam tshuam rau Clavamox ntsiav tshuaj.

Clavamox Drops Indications

Clavamox tee yog qhia rau kev kho mob ntawm:

DOG: Daim tawv nqaij thiab cov ntaub so ntswg mos xws li qhov txhab, abscesses, cellulitis, superficial/juvenile thiab deep pyoderma vim yog cov kab mob uas raug kab mob hauv qab no:

● β-lactamase tsim tawm Staphylococcus aureus

● uas tsis yog-β-lactamase tsim Staphylococcus aureus

qhov sib txawv ntawm methylprednisolone thiab prednisone

Staphylococcus spp., Streptococcus spp ,ua E. coli

Cov kab mob urinary Tract Infections (cystitis) vim muaj kab mob.

Gingivitis cuam tshuam nrog kev kis kab mob vim muaj kab mob aerobic thiab anaerobic kab mob.

CAWS: Daim tawv nqaij thiab cov ntaub so ntswg mos xws li qhov txhab, abscesses, thiab cellulitis / dermatitis vim muaj kab mob ntawm cov kab mob hauv qab no:

● β-lactamase tsim tawm Staphylococcus aureus

● uas tsis yog-β-lactamase tsim Staphylococcus aureus

Staphylococcus spp., Streptococcus spp., E. coli, thiab Pasteurella ua spp.

Cov kab mob urinary Tract Infections (cystitis) vim muaj kab mob.

Kev kho yuav pib nrog Clavamox ua ntej tau txais txiaj ntsig los ntawm kev tshawb fawb bacteriological thiab susceptibility. Ib kab lis kev cai yuav tsum tau txais ua ntej kev kho mob txhawm rau txiav txim siab qhov cuam tshuam ntawm cov kab mob me me rau Clavamox. Tom qab kev txiav txim siab ntawm qhov tshwm sim ntawm kev raug mob thiab cov lus teb rau kev kho mob rau cov tshuaj, kev kho yuav raug rov ntsuam xyuas dua.

Contraindications

Kev siv cov tshuaj no yog contraindicated nyob rau hauv cov tsiaj uas muaj keeb kwm ntawm kev tsis haum tshuaj rau ib yam ntawm cov penicillins los yog cephalosporins.

Dosage thiab Administration

DOGS: Qhov pom zoo noj ntawm qhov ncauj ntawm amoxicillin / clavulanic acid ib kg ntawm lub cev qhov hnyav yog 12.5 mg ob zaug ib hnub rau daim tawv nqaij thiab cov nqaij mos thiab kab mob urinary kab mob , thiab 13.75 mg ob zaug ib hnub rau gingivitis .

hydrocortisone qab zib usp 2.5

Kab mob ntawm daim tawv nqaij thiab cov nqaij mos xws li abscesses, cellulitis, qhov txhab, thiab sab nrauv / menyuam yaus pyoderma yuav tsum tau kho rau 5 mus rau 7 hnub. Gingivitis yuav tsum tau kho rau 7 mus rau 10 hnub. Txuas ntxiv kev tswj hwm rau 48 teev tom qab tag nrho cov cim tau ploj lawm. Yog tias tsis pom cov lus teb tom qab 5 hnub ntawm kev kho mob, kev kho mob yuav tsum tau txiav thiab rov ntsuam xyuas dua. Sib sib zog nqus pyoderma yuav xav tau kev kho mob rau 21 hnub. Kab mob urinary ib ntsuj av tej zaum yuav xav tau kev kho mob li 10 mus rau 14 hnub lossis ntev dua. Qhov siab tshaj plaws ntawm kev kho mob yuav tsum tsis pub tshaj 30 hnub.

CATS: Qhov pom zoo noj qhov ncauj yog 62.5 mg ntawm amoxicillin / clavulanic acid (1 mL) rau ib tug tsiaj ob zaug ib hnub twg.

Kab mob ntawm daim tawv nqaij thiab cov nqaij mos xws li abscesses thiab cellulitis / dermatitis yuav tsum tau kho rau 5 mus rau 7 hnub. Txuas ntxiv kev tswj hwm rau 48 teev tom qab tag nrho cov cim tau ploj lawm. Yog tias tsis pom cov lus teb tom qab 3 hnub ntawm kev kho mob, kev kho mob yuav tsum tau txiav thiab rov ntsuam xyuas dua. Kab mob urinary ib ntsuj av tej zaum yuav xav tau kev kho mob li 10 mus rau 14 hnub lossis ntev dua. Qhov siab tshaj plaws ntawm kev kho mob yuav tsum tsis pub tshaj 30 hnub.

COV TSWV YIM TSHIAB: Ntxiv 14 mL dej rau hauv lub raj mis kom tag nrho ntim ntawm 15 mL thiab co lub zog. Txhua mL ntawm reconstituted suspension muaj 50 mg ntawm amoxicillin (raws li amoxicillin trihydrate) thiab 12.5 mg ntawm clavulanic acid (raws li clavulanate potassium). Thaum rov ua dua, khaws cov kev ncua ntawm qhov kub ntawm 2 txog 8 ° C. Ib qho uas tsis siv yuav tsum muab pov tseg tom qab 7 hnub.

Ceeb toom

Khaws kom deb ntawm cov menyuam yaus.

CEEB TOOM: Tsis txhob siv rau hauv cov tsiaj khaws cia rau kev yug me nyuam vim tsis tau tsim kev nyab xeeb. Nyob rau hauv cov ntaub ntawv ntawm anaphylaxis, muab tshuaj epinephrine.

Cia

Khaws cov khoom tsis tsim nyog ntawm qhov kub ntawm 15 txog 25 ° C.

Zoetis yog lub cim lag luam thiab Clavamox yog lub cim lag luam ntawm Zoetis lossis nws cov ntawv tso cai, siv raws li daim ntawv tso cai los ntawm Zoetis Canada Inc.

Zoetis Canada Inc., Kirkland QC H9H 4M7

8016-11-2

P1517409

CPN: 1198027.7 ib

ZOTIS CANADA INC.
16,740 TRANS-CANADA HIGHWAY, KIRKLAND, QC, H9H 4M7
Order Desk: 800-663-8888 ib
Technical Services Canada: 800-461-0917 Ib
Technical Services USA: 800-366-5288
Lub Vev Xaib: www.zoetis.ca
Txhua qhov kev siv zog tau ua los xyuas kom meej qhov tseeb ntawm Clavamox Drops cov ntaub ntawv luam tawm saum toj no. Txawm li cas los xij, nws tseem yog lub luag haujlwm ntawm cov neeg nyeem kom paub lawv tus kheej nrog cov ntaub ntawv ntawm cov khoom lag luam uas muaj nyob rau ntawm Canadian cov khoom lag luam daim ntawv lo lossis pob ntim.

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