Puas yog gabapentin ua rau cem quav?

Teb chaws

los ntawm tshuaj.com

Gabapentin tuaj yeem ua rau cem quav, tab sis nws tsis yog qhov tshwm sim tshwm sim. Hauv kev sim tshuaj ntawm cov neeg laus noj gabapentin rau cov hlab ntsha, tsuas yog li 4% ntawm cov neeg tau qhia cem quav. Qee cov neeg hauv cov kev sim no tau siv tshuaj tsis muaj zog (placebo). Kwv yees li 2% ntawm cov neeg siv cov placebo kuj tau tshaj tawm cem quav, yog li qhov feem pua ​​​​ntawm cov neeg cem quav thaum noj gabapentin yog qhov tsawg dua 4%.

Hauv kev sim tshuaj ntawm cov neeg muaj hnub nyoog 12 xyoos thiab tshaj li kev noj gabapentin rau kev qaug dab peg, kwv yees li 2% qhia cem quav raws li kev mob tshwm sim. Tawm ntawm cov neeg siv cov placebo, 1% kuj tau tshaj tawm cem quav.



Hauv kev sim tshuaj kho mob ntawm gabapentin los kho cov hlab ntsha hauv cov neeg laus, cov kev mob tshwm sim feem ntau yog:

Invokana thiab metformin ua ke
  • kiv taub hau
  • Kev pw tsaug zog
  • o ntawm txhais tes lossis ko taw (peripheral edema)

Hauv kev sim tshuaj ntsuam xyuas cov neeg laus dua 12 xyoo noj gabapentin los kho tus mob qaug dab peg, cov kev mob tshwm sim feem ntau yog pw tsaug zog thiab clumsiness (ataxia).

mob plab sab xis hauv qab kab tav

Kev xav txog kev tuag lossis kev tua tus kheej yog lwm qhov tsis tshua muaj tab sis tseem ceeb ntawm gabapentin, tshwm sim hauv kwv yees li 1 ntawm 500 tus neeg. Cov kev xav no tuaj yeem tshwm sim hauv ib lub lis piam ntawm kev pib gabapentin. Hu rau koj tus kws kho mob tam sim ntawd yog tias koj muaj kev hloov pauv txawv txawv hauv lub siab lossis tus cwj pwm, lossis ib qho ntawm cov tsos mob no:

  • Xav txog kev tua tus kheej lossis tuag
  • Kev sim tua tus kheej
  • Kev nyuaj siab, tshiab los yog zuj zus
  • Kev ntxhov siab, tshiab lossis hnyav dua
  • Panic tawm tsam

Xyoo 2019, US Food and Drug Administration (FDA) tau ntxiv lwm qhov lus ceeb toom tseem ceeb txog gabapentin: Thaum cov tshuaj no tau noj nrog tshuaj kho mob opioid lossis siv los ntawm tus neeg mob ntsws ntev xws li mob ntsws ntsws (COPD), nws yuav ua rau mob hnyav. thiab tej zaum yuav ua rau tuag taus ua pa (kev nyuaj siab ua pa). Ua ntej pib gabapentin, qhia rau koj tus kws kho mob paub yog tias koj tab tom noj tshuaj opioid, lossis yog tias koj tau kuaj mob ntsws.

Txawm hais tias koj muaj kev phiv los ntawm gabapentin, nws tseem ceeb heev kom tsis txhob noj nws tam sim ntawd ntawm koj tus kheej. Cov tshuaj no yuav tsum tau txo lub sij hawm (tapered) los ntawm koj tus kws kho mob. Kev nres tam sim ntawd tuaj yeem ua rau tshem tawm cov tsos mob xws li:

  • Kev ntxhov siab
  • Insomnia
  • Ntshai
  • Mob

Yog tias koj noj gabapentin los tswj kev qaug dab peg, nres tam sim ntawd yuav ua rau koj muaj feem yuav qaug dab peg.

Cov ntaub ntawv
  1. Food and Drug Administration (FDA). Neurontin (gabapentin). Lub Kaum Hli 2017. Muaj nyob ntawm: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020235s064_020882s047_021129s046lbl.pdf . [ Nkag mus rau Lub Peb Hlis 5, 2021].
  2. Pfizer. Gabapentin. Lub Kaum Ob Hlis 2020. Muaj nyob ntawm: labeling.pfizer.com/ShowLabeling.aspx?id=630 . [ Nkag mus rau Lub Peb Hlis 5, 2021].
  3. US National Library of Medicine. Gabapentin. Lub Tsib Hlis 15, 2020. Muaj nyob ntawm: https://medlineplus.gov/druginfo/meds/a694007.html . [ Nkag mus rau Lub Peb Hlis 5, 2021].
  4. Food and Drug Administration (FDA). FDA hauv luv luv: FDA xav tau cov lus ceeb toom tshiab rau gabapentinoids txog kev pheej hmoo ntawm kev ua pa nyuaj. Kaum Ob Hlis 19, 2019. Muaj nyob ntawm: Tsab ntawv xov xwm no tshwm sim thawj zaug https://www.fda.gov/news-events/fda-brief/fda-brief-fda-requires-new-warnings-gabapentinoids-about-risk-respiratory-depression . [ Nkag mus rau Lub Peb Hlis 5, 2021].

Cov Lus Nug Txog Kev Kho Mob

Cov Ntaub Ntawv Tshuaj

Cov pab pawg muaj feem cuam tshuam

  • Gabapentin (391 nqe lus nug, 1821 cov tswv cuab)
  • cem quav (191 nqe lus nug, 569 tus tswv cuab)