Puas yog topiramate ua rau poob phaus?

Teb chaws

Ntsiab Lus

• Yog lawm, topiramate ( Topamax ) tau pom tias ua rau poob phaus thaum siv rau ob qho tib si tswj kev qaug dab peg thiab kev tiv thaiv migraine.
• Anorexia (tsis qab los noj mov), uas yuav ua rau kom poob phaus, kuj tau qhia nyob rau hauv cov kev tshawb fawb nyob rau hauv cov me nyuam thiab cov neeg laus, txawm hais tias tsis muaj kev sib raug zoo nyob rau hauv kev tshawb fawb.
• Topiramate (siv los ntawm nws tus kheej) tsis tau pom zoo tshwj xeeb los ntawm FDA rau kev poob phaus, tab sis qee tus kws kho mob yuav sau ntawv rau nws yog tias koj qaug dab peg lossis mob migraine thiab xav kom poob phaus, thiab. Cov kev mob tshwm sim tuaj yeem cuam tshuam nws txoj kev siv rau kev poob phaus thaum siv ib leeg.
• Topiramate muaj nyob rau hauv ib qho tshuaj ntxiv-tso tso cai rau kev poob phaus hu ua Qsymia ( phentermine thiab topiramate ). Phentermine yog ib qho kev noj qab haus huv suppressant ( anorexiant ) nrog cov yam ntxwv zoo ib yam li amphetamine. Qsymia yog siv nrog rau kev noj haus thiab kev tawm dag zog los kho cov neeg uas rog rog, lossis rog dhau nrog lwm yam kev pheej hmoo xws li ntshav siab, roj cholesterol siab lossis ntshav qab zib hom 2.

Dab tsi yog topiramate siv rau?

Topiramate yog cais raws li ib tug tshuaj anticonvulsant (kua) tshuaj .

• Topiramate yog ib qho tshuaj noj, noj ib leeg lossis nrog lwm cov tshuaj los tswj qee yam qaug dab peg vim mob qaug dab peg . Topiramate yog siv rau kev kho mob ntawm ib feem ntawm qhov pib qaug dab peg, thawj generalized tonic-clonic qaug dab peg, thiab qaug dab peg txuam nrog Lennox-Gastaut Syndrome.
• Nws kuj yog siv rau kev tiv thaiv ntawm mob taub hau migraine . Topiramate yuav tsis tso tseg migraine thaum nws pib.

Cov npe tshuaj rau topiramate muaj nyob hauv Asmeskas suav nrog Topamax , Trokendi XR , Topamax Sprinkle (tso tseg), thiab Qudexy XR . Kev siv thiab ntau npaum cov ntaub ntawv sib txawv ntawm cov khoom, thiab tej zaum yuav tsis hloov pauv.

tshuaj dawb teva 2210

Hais txog : Poob qhov hnyav thiab noj tshuaj noj: Cov kev xaiv kom paub

Puas tau poob phaus tshwm sim hauv kev tshawb fawb nrog topiramate?

Yog lawm, kev poob phaus tau tshaj tawm hauv kev tshawb fawb ntawm cov menyuam yaus thiab cov neeg laus. Feem ntau, kev poob phaus tau pom nyob rau hauv 6% mus rau 17% ntawm cov neeg mob, thiab muaj peev xwm nce nrog ntau dua.

Cov neeg laus

Tswj kev qaug dab peg - Cov kev mob tshwm sim tau raug soj ntsuam hauv cov neeg mob 16 xyoo thiab laus dua noj topiramate ( Topamax ) ib leeg (tsis muaj lwm yam tshuaj qaug dab peg) ntawm ob koob: 50 mg / hnub lossis 400 mg / hnub. Kev poob phaus thiab tsis qab los noj mov (anorexia) yog ob qho kev tshwm sim feem ntau tshaj tawm.

Hauv cov neeg mob noj cov tshuaj qis dua 50 mg / hnub ntawm topiramate, qhov hnyav tau tshwm sim hauv 6% ntawm cov neeg mob, thiab ntau dua 200 mg / hnub koob tshuaj, qhov poob phaus tau tshaj tawm hauv 17% ntawm cov neeg mob. Anorexia (tsis qab los noj mov), uas yuav ua rau poob phaus, kuj pom nyob rau hauv 4% thiab 14% ntawm cov neeg mob, feem.

Thaum topiramate (Topamax) tau kawm nyob rau hauv cov neeg laus uas siv nws ntxiv rau lwm cov tshuaj (adjunctive kho) rau kev qaug dab peg, qhov hnyav tau tshwm sim hauv 9% ntawm cov neeg mob tau txais 200 mg / hnub rau 400 mg / hnub, thiab 3% ntawm cov neeg noj. ib qho placebo (ib ntsiav tshuaj tsis muaj zog). Hauv cov menyuam yaus, cov lej no yog 9% thiab 1%, feem.

Kev tiv thaiv migraine - Hauv cov neeg laus siv koob tshuaj 50 mg / hnub rau kev tiv thaiv kab mob migraine, 6% ntawm cov neeg mob tau poob phaus, thaum nyob hauv pawg 100 mg / hnub, 9% ntawm cov neeg mob tau tshaj tawm qhov hnyav. Hauv qhov sib piv, 1% ntawm cov neeg mob hauv pawg placebo poob phaus. Anorexia tshwm sim hauv 9% mus rau 15% ntawm cov neeg noj topiramate, tab sis kuj tshwm sim hauv 6% ntawm cov neeg siv cov placebo.

Me nyuam

qaug dab peg - Hauv cov menyuam yaus hnub nyoog 6 txog 15 xyoos noj 50 mg / hnub koob tshuaj topiramate (Topamax) rau qaug dab peg, qhov hnyav tau pom hauv 7% ntawm cov neeg mob. Hauv pawg ntau npaum li cas (400 mg / hnub) qhov poob phaus tshwm sim hauv 17% ntawm cov menyuam yaus. Anorexia (tsis qab los noj mov) tsis tau tshaj tawm nyob rau hauv ob pawg koob tshuaj rau cov menyuam yaus hnub nyoog 6 txog 15 xyoos.

Kuv puas tuaj yeem noj ibuprofen nrog mucinex

Kev tiv thaiv migraine - Hauv cov tub ntxhais hluas hnub nyoog 12 txog 17 xyoo, qhov hnyav tau tshwm sim hauv 7% (50 mg / hnub koob) thiab 4% (100 mg / hnub) piv rau 2% hauv pawg placebo. Anorexia tshwm sim hauv 9% mus rau 10% ntawm cov neeg mob noj topiramate thiab 4% ntawm cov neeg siv cov placebo.

carprofen rau cov dev noj daim ntawv

Kev kho tsis txuas ntxiv nrog topiramate

Kev poob phaus tsis tau teev nyob rau hauv cov khoom lag luam raws li ib qho laj thawj vim li cas cov neeg mob txiav kev kho mob nrog topiramate (Topamax).

Hauv kev tshawb fawb, qee tus neeg mob tau tso tseg kev kho mob vim muaj lwm yam kev mob tshwm sim.

• Hauv cov neeg laus hnub nyoog 16 xyoo thiab laus dua hauv cov koob tshuaj ntau (400 mg / hnub), 21% ntawm cov neeg mob nres kev kho mob vim muaj teeb meem nrog kev nco, qaug zog, asthenia (tsis muaj zog), insomnia (nyuaj pw tsaug zog), somnolence (drowsiness heev), thiab paresthesia (pins thiab koob los yog tingling nyob rau hauv extremities).
• Hauv cov menyuam yaus hnub nyoog 6 txog 15 xyoo nyob rau hauv cov koob tshuaj ntau (400 mg / hnub), 14% ntawm cov neeg mob tau tso tseg kev kho mob vim muaj teeb meem nrog kev mloog / kev saib xyuas, kub taub hau, dej ntws tawm, thiab tsis meej pem.

Topiramate txuas nrog ntau lwm yam kev mob tshwm sim , nrog rau xeev siab, mob plab, thiab saj perversion, uas yuav cuam tshuam qhov hnyav poob lossis anorexia.

Qhov no tsis yog tag nrho cov ntaub ntawv koj xav paub txog topiramate kom muaj kev nyab xeeb thiab siv tau zoo. Saib xyuas lub tag nrho topiramate (Topamax) cov ntaub ntawv ntawm no , thiab sib tham txog qhov no thiab cov lus nug uas koj muaj nrog koj tus kws kho mob lossis lwm tus kws kho mob.

• Kramer CK, Leitão CB, Pinto LC, et al. Kev ua tau zoo thiab kev nyab xeeb ntawm topiramate ntawm kev poob phaus: ib qho kev tshuaj ntsuam meta ntawm kev sim tswj randomized. Obes Rev. 2011 May;12(5):e338-47. PIB: 21438989
• Topiramate. Tshuaj @FDA: FDA pom zoo tshuaj. Nkag mus rau Lub Ib Hlis 29, 2021 ntawm https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm
• Topamax [cov khoom lag luam monograph]. Drugs.com. Nkag mus rau Lub Ib Hlis 28, 2021 ntawm find-drugs-conditionspro/topamax.html
• Qysmia [cov khoom lag luam monograph]. Drugs.com. Tau txais Lub Ib Hlis 29, 2021 thaum find-drugs-conditionspro/qsymia.html

Cov Lus Nug Txog Kev Kho Mob

Cov Ntaub Ntawv Tshuaj

• Topiramate Cov ntaub ntawv rau cov neeg siv khoom
• Topiramate Cov Ntaub Ntawv rau Cov Kws Kho Mob (nrog rau cov lus qhia txog kev noj tshuaj)
• Cov teebmeem ntawm Topiramate (muaj meej)

Cov pab pawg txhawb nqa ntsig txog

• Topiramate (43 nqe lus nug, 238 tus tswv cuab)
• Kev Tiv Thaiv Migraine (92 nqe lus nug, 312 tus tswv cuab)
• qaug dab peg (115 nqe lus nug, 759 tus tswv cuab)
• Mob qaug dab peg (62 nqe lus nug, 378 tus tswv cuab)
• Migraine Prophylaxis (47 nqe lus nug, 76 tus tswv cuab)
• Kev tiv thaiv qaug dab peg (39 nqe lus nug, 134 tus tswv cuab)
• Kev Txhaum Cai Prophylaxis (19 nqe lus nug, 23 tus tswv cuab)
• Lennox-Gastaut Syndrome (11 nqe lus nug, 7 tus tswv cuab)