Gabapentin Dosage

Siv rau lub zog hauv qab no: 800 mg; 600 mg; 100 mg; 300 mg; 400 mg; 250 mg / 5 mL; enacarbil 600 mg; 300 mg / 24 teev; 600 mg / 24 teev; 300 mg / 24 teev - 600 mg / 24 teev; enacarbil 300 mg

Ib txwm Adult Dose rau:

Ib txwm Pediatric Dose rau:

Cov lus qhia txog kev noj tshuaj ntxiv:

Ib txwm siv rau tus neeg laus koob tshuaj rau qaug dab peg

Thawj koob tshuaj: 300 mg ntawm qhov ncauj 3 zaug hauv ib hnub
Kev saib xyuas koob tshuaj: 300 mus rau 600 mg ntawm qhov ncauj 3 zaug hauv ib hnub
Cov koob tshuaj ntau tshaj: 2400 txog 3600 mg / hnub

Cov lus pom:
-Cov koob tshuaj txog li 2400 mg / hnub tau raug lees paub zoo hauv kev tshawb fawb mus ntev; koob tshuaj 3600 mg/hnub tau siv nyob rau hauv cov neeg mob me me rau lub sijhawm luv luv thiab tau txais txiaj ntsig zoo.
-Lub sij hawm siab tshaj plaws ntawm koob tshuaj yuav tsum tsis pub tshaj 12 teev.
-Qhov kev nyab xeeb thiab kev ua tau zoo ntawm gabapentin muaj nyob rau hauv lub npe lag luam Gralise lossis Horizant tsis tau kawm hauv cov neeg mob qaug dab peg.

Siv: Adjunctive therapy nyob rau hauv kev kho mob ntawm ib feem pib qaug dab peg, nrog thiab tsis muaj lwm yam generalization



Ib txwm siv rau cov neeg laus noj rau Postherpetic Neuralgia

Kev tso tawm tam sim:
Thawj koob tshuaj :
Hnub 1: 300 mg ntawm qhov ncauj ib zaug
Hnub 2: 300 mg ntawm qhov ncauj 2 zaug ib hnub
Hnub 3: 300 mg ntawm qhov ncauj 3 zaug hauv ib hnub
-Titrate koob tshuaj raws li xav tau rau kev kho mob
Cov koob tshuaj tu: 900 txog 1800 mg / hnub ntawm qhov ncauj hauv 3 qhov sib faib
Cov koob tshuaj ntau tshaj: 1800 mg ib hnub twg

Extended-tso: Gralise (gabapentin) 24-teev ncua-tso ntsiav tshuaj:
Thawj koob tshuaj:
Hnub 1: 300 mg ntawm qhov ncauj nrog noj hmo
Hnub 2: 600 mg ntawm qhov ncauj nrog noj hmo
Hnub 3 txog 6: 900 mg ntawm qhov ncauj nrog noj hmo
Hnub 7 txog 10: 1200 mg ntawm qhov ncauj nrog noj hmo
Hnub 11 txog 14: 1500 mg ntawm qhov ncauj nrog noj hmo
Cov koob tshuaj tu (Hnub 15 thiab txuas ntxiv): 1800 mg ntawm qhov ncauj nrog noj hmo

Extended-tso: Kab rov tav (gabapentin enacarbil) txuas ntxiv tso cov ntsiav tshuaj :
Thawj koob tshuaj:
Hnub 1 txog Hnub 3: 600 mg ntawm qhov ncauj ib hnub ib zaug
Cov koob tshuaj tu (Hnub 4 thiab txuas ntxiv): 600 mg ntawm qhov ncauj ob zaug ib hnub
Cov koob tshuaj ntau tshaj: 1200 mg / hnub

Cov lus pom:
-Cov khoom txuas ntxiv-tso tawm Gralise thiab Horizant tsis tuaj yeem hloov pauv ntawm ib leeg lossis lwm yam khoom gabapentin vim qhov sib txawv ntawm cov tshuaj pharmacokinetic.
-Nyob rau hauv kev sim tshuaj, ntau tshaj qhov koob tshuaj tsis tau pom cov txiaj ntsig ntxiv, tab sis cov koob tshuaj ntau dua tau ua rau muaj kev phiv ntau ntxiv.

Siv: Rau kev tswj ntawm postherpetic neuralgia.

koj puas tuaj yeem siv tylenol nrog benadryl

Ib txwm siv rau cov neeg laus noj rau Restless Legs Syndrome

600 mg ntawm qhov ncauj ib hnub nrog zaub mov thaum txog 5 teev tsaus ntuj
Cov koob tshuaj ntau tshaj: 600 mg

Saib :
-Gabapentin enacarbil muaj nyob rau hauv lub npe lag luam Horizant yog tib yam khoom gabapentin pom zoo rau kev kho mob ntawm Restless Legs Syndrome (RLS).
-Ib koob tshuaj txhua hnub ntawm 1200 mg tsis muaj txiaj ntsig ntxiv piv nrog 600 mg koob, tab sis ua rau muaj kev cuam tshuam tsis zoo.
-Cov tshuaj no tsis pom zoo rau cov neeg mob uas yuav tsum tau pw thaum nruab hnub thiab tsaug zog thaum hmo ntuj.

Siv: Rau kev kho mob ntawm nruab nrab-rau-mob thawj RLS hauv cov neeg laus.

Ib txwm Pediatric Dose rau Epilepsy

Hnub nyoog: 3 txog 11 xyoos:
Thawj koob tshuaj: 10 mus rau 15 mg / kg / hnub ntawm qhov ncauj hauv 3 qhov sib faib
Kho koob tshuaj:
Hnub nyoog: 3 mus rau 4 xyoos: 40 mg / kg / hnub ntawm qhov ncauj thiab hauv 3 qhov sib faib tshuaj (3 zaug hauv ib hnub)
Hnub nyoog: 5 mus rau 11 xyoos: 25 mus rau 35 mg / kg / hnub hauv 3 faib koob tshuaj (3 zaug hauv ib hnub)
Cov koob tshuaj ntau tshaj: Cov koob tshuaj txog li 50 mg / kg / hnub tau raug lees paub zoo hauv kev tshawb fawb soj ntsuam ntev.

Hnub nyoog: 12 xyoos lossis tshaj saud:
Thawj koob tshuaj: 300 mg ntawm qhov ncauj 3 zaug hauv ib hnub
Kev saib xyuas koob tshuaj: 300 mus rau 600 mg ntawm qhov ncauj 3 zaug hauv ib hnub
Cov koob tshuaj ntau tshaj: 2400 txog 3600 mg / hnub; koob tshuaj txog li 2400 mg/hnub tau txais kev pom zoo hauv kev tshawb fawb mus ntev; koob tshuaj 3600 mg/hnub tau siv nyob rau hauv cov neeg mob me me rau lub sijhawm luv luv thiab tau txais txiaj ntsig zoo.

Cov lus pom:
-Cov koob tshuaj pib yuav tsum tau titrated tshaj 3 hnub rau cov tshuaj noj uas pom zoo.
-Lub sij hawm siab tshaj plaws ntawm koob tshuaj yuav tsum tsis pub tshaj 12 teev.
-Kev nyab xeeb thiab kev ua tau zoo ntawm gabapentin muaj nyob rau hauv lub npe lag luam Gralise lossis Horizant tsis tau kawm hauv cov neeg mob menyuam yaus thiab cov neeg mob qaug dab peg.

Siv: Kev kho mob ntxiv rau hauv kev kho mob ntawm qee qhov pib qaug dab peg, nrog thiab tsis muaj kev cuam tshuam loj hauv cov neeg mob hnub nyoog 3 xyoos thiab laus dua.

Renal Dose Adjustments

Kev tso tawm tam sim:
12 xyoos lossis tshaj saud: Cov koob tshuaj yuav tsum muab faib thiab muab 3 zaug hauv ib hnub
-CrCl 60 mL / min lossis ntau dua: 900 txog 3600 mg / hnub
-CrCl 30 txog 59 mL / min: 400 txog 1400 mg / hnub
-CrCl 15 txog 29 mL / min: 200 txog 700 mg / hnub
-CrCl 15 mL / min: 100 mus rau 300 mg / hnub (txo txhua hnub koob tshuaj rau CrCl)
Tsawg dua 12 xyoos: Cov ntaub ntawv tsis muaj

Kev Tshaj Tawm Ntxiv: Gralise (24-teev ncua-tso ntsiav tshuaj):
-CrCl ntau dua lossis sib npaug li 60 mL / min: Tsis pom zoo hloov kho
-CrCl 30 mus rau 60 mL / min: 600 mus rau 1800 mg ntawm qhov ncauj nrog noj hmo.
-CrCl tsawg dua 30 mL / min: Tsis pom zoo

Extended-tso: Kab rov tav (gabapentin enacarbil ncua-tso ntsiav tshuaj):
TSIS TXAUS SIAB SYNDROME :
-CrCl ntau dua lossis sib npaug li 60 mL / min: Tsis pom zoo hloov kho
-CrCl 30 txog 59 mL / min: Thawj koob tshuaj: 300 mg ntawm qhov ncauj ib hnub ib zaug thiab nce mus rau 600 mg raws li xav tau
-CrCl 15 txog 29 mL / min: 300 mg ntawm qhov ncauj ib hnub ib zaug
-CrCl tsawg dua 15 mL / min: 300 mg ntawm qhov ncauj txhua hnub
POSTHERPETIC NEURALGIA :
-CrCl 60 mL / min lossis ntau dua: Tsis pom zoo hloov kho
-CrCl 30 txog 59 mL / min: Thawj koob tshuaj: 300 mg ntawm qhov ncauj ib hnub rau 3 hnub, tom qab ntawd 300 mg ntawm qhov ncauj 2 zaug hauv ib hnub; nce mus rau 600 mg ntawm qhov ncauj 2 zaug hauv ib hnub raws li xav tau
-CrCl 15 txog 29 mL / min: Thawj koob tshuaj: 300 mg ntawm qhov ncauj thaum sawv ntxov hnub 1 thiab hnub 3; ces 300 mg ib hnub ib zaug thaum sawv ntxov; tuaj yeem nce mus rau 300 mg ntawm qhov ncauj 2 zaug hauv ib hnub yog tias xav tau
-CrCl tsawg dua 15 mL / min: 300 mg ntawm qhov ncauj txhua hnub; nce mus rau 300 mg ntawm qhov ncauj ib zaug ib hnub yog tias xav tau

prednisone cov kev mob tshwm sim mus sij hawm ntev

Kev Kho Mob Siab

Cov ntaub ntawv tsis muaj

Kev Kho Tshuaj

Cov neeg mob Geriatric: Vim tias cov neeg mob laus feem ntau yuav muaj lub raum tsis ua haujlwm, cov tshuaj no yuav tsum tau hloov kho raws li CrCl qhov tseem ceeb.

Kev rho tawm yeeb tshuaj:
-Cov tshuaj yuav tsum maj mam rho tawm
-Yog tias cov tshuaj tso tawm tam sim ntawd raug txo, txiav tawm, lossis hloov nrog lwm cov tshuaj, qhov no yuav tsum tau ua kom maj mam dhau qhov tsawg kawg ntawm 1 lub lis piam (lub sijhawm ntev dua yuav xav tau ntawm kev txiav txim siab ntawm tus kws kho mob)
-Yog tias Gralise raug txiav tawm, qhov no yuav tsum txiav tawm tsawg kawg ntawm 1 lub lis piam lossis ntev dua
-Yog tias Horizant raug txiav tawm hauv tus neeg mob tau txais 600 mg / hnub lossis tsawg dua, kev txiav tawm yuav ua tiav yam tsis muaj kev sib tw.
-Yog tias Horizant raug txiav tawm hauv cov neeg mob tau txais cov tshuaj no ob zaug hauv ib hnub, txo qis rau ib hnub ib zaug rau 1 lub lis piam ua ntej txiav tawm.

Cov kev ceev faj

CONTRAINDICATIONS:
-Hypersensitivity rau active tshuaj los yog tej yam khoom excipients

Kev nyab xeeb thiab kev ua tau zoo tsis tau tsim nyob rau hauv cov neeg mob hnub nyoog qis dua 18 xyoo hauv kev tswj hwm ntawm postherpetic neuralgia lossis Restless Leg Syndrome.
Kev nyab xeeb thiab kev ua tau zoo tsis tau tsim nyob rau hauv cov neeg mob uas muaj hnub nyoog qis dua 3 xyoos hauv kev kho mob ntawm kev qaug dab peg ib nrab.
Kev nyab xeeb thiab kev ua tau zoo tsis tau tsim nyob rau hauv cov neeg mob hnub nyoog qis dua 18 xyoo rau gabapentin muaj nyob rau hauv cov npe lag luam Gralise lossis Horizant.

Nrog rau WARNINGS seem rau kev ceev faj ntxiv.

Dialysis

Kev tso tawm tam sim: 12 xyoo lossis tshaj saud:
- Kho cov koob tshuaj raws li CrCl thiab muab cov koob tshuaj tom qab hemodialysis ntxiv tom qab txhua 4 teev ntawm hemodialysis: Saib cov khoom lag luam sau npe rau cov tshuaj tom qab hemodialysis ntxiv.

Extended-tso tawm:
-Gralise: Hemodialysis: Tsis pom zoo
- Kab rov tav (gabapentin enacarbil):
TSIS TXAUS SIAB SYNDROME :
-CrCl tsawg dua 15 mL / min ntawm hemodialysis: Tsis pom zoo
POSTHERPETIC NEURALGIA :
-CrCl tsawg dua 15 mL / min ntawm hemodialysis: 300 mg ntawm qhov ncauj tom qab txhua qhov lim ntshav; nce mus rau 600 mg ntawm qhov ncauj tom qab txhua lub lim piam yog tias xav tau

Lwm Cov Lus Qhia

Tswv yim tswv yim :
Kev tso tawm tam sim:
- Noj nrog lossis tsis noj mov
- Ncua capsules tag nrho nrog dej
-Yog tias cov ntsiav tshuaj 600 mg lossis 800 mg tau qhab nia los tswj cov ntsiav tshuaj ib nrab, cov ntsiav tshuaj ib nrab uas tsis tau siv yuav tsum tau siv ua koob tshuaj ntxiv; yog tias ib nrab ntsiav tshuaj tsis siv nyob rau hauv 28 hnub ntawm kev faib, cov ntsiav tshuaj tau qhab nia yuav tsum muab pov tseg
Extended-tso tawm:
-Horizant (gabapentin enacarbil): Noj ib hnub ib zaug txog 5 teev tsaus ntuj rau Restless Leg Syndrome los yog ob zaug ib hnub twg thaum sawv ntxov thiab yav tsaus ntuj rau Postherpetic Neuralgia; nqos ntsiav tshuaj tag nrho nrog zaub mov; tsis txhob txiav, tsoo, lossis zom cov ntsiav tshuaj
-Gralise ncua-tso ntsiav tshuaj yuav tsum tau noj ib zaug ib hnub nrog noj hmo; tsis txhob txiav, tsoo, lossis zom cov ntsiav tshuaj
-Horizant thiab Gralise tsis sib hloov nrog ib leeg lossis lwm yam khoom gabapentin

TSIS MUAJ DOSES:
Kab rov tav: Yog tias tsis muaj koob tshuaj, hla qhov koob tshuaj uas tsis tau thiab noj cov tshuaj ntxiv tom ntej ntawm lub sijhawm teem tseg
Gralise: Yog tias tsis noj tshuaj, noj nrog zaub mov kom sai li sai tau lawv nco qab; yog tias nws yuav luag lub sijhawm rau koob tshuaj ntxiv, hla qhov koob tshuaj uas tsis tau thiab noj cov tshuaj ntxiv tom ntej ntawm lub sijhawm; tsis txhob noj ob koob tshuaj tib lub sijhawm

Cia:
-Kev daws qhov ncauj: Khaws rau hauv lub tub yees (2C txog 8C [36F txog 46F])

General :
-Yog tias gabapentin raug txiav tawm thiab / lossis lwm yam tshuaj tiv thaiv kab mob ntxiv rau kev kho mob, qhov no yuav tsum tau ua kom maj mam li tsawg kawg 1 lub lis piam.

Saib xyuas:
- Saib xyuas kev nyuaj siab ua pa hauv cov neeg mob uas muaj kev pheej hmoo (cov neeg mob uas muaj kev ua pa tsis zoo thiab / lossis cov tshuaj tiv thaiv kev nyuaj siab CNS concomitant)
- Saib xyuas qhov tshwm sim ntawm kev ntxhov siab hnyav zuj zus, kev xav tua tus kheej, lossis tus cwj pwm, thiab / lossis kev hloov pauv txawv txawv hauv lub siab lossis tus cwj pwm

Cov lus qhia rau tus neeg mob:
-Cov neeg mob yuav tsum tau qhia kom nyeem US FDA-pom zoo daim ntawv lo rau tus neeg mob (Kev Qhia Tshuaj).
-Cov neeg mob, tsev neeg, thiab cov neeg saib xyuas yuav tsum nkag siab tias cov tshuaj no tuaj yeem ua rau muaj kev pheej hmoo ntawm kev xav tua tus kheej thiab tus cwj pwm thiab lawv yuav tsum tau qhia kom qhia txog kev hloov pauv ntawm lub siab lossis tus cwj pwm, kev nyuaj siab, lossis kev xav tua tus kheej los yog tus cwj pwm rau lawv tus kws kho mob tam sim ntawd. .
-Cov neeg mob, tsev neeg, thiab cov neeg zov me nyuam yuav tsum tau qhia kom tshaj tawm cov pob liab liab lossis lwm yam cim lossis cov tsos mob ntawm qhov tsis hnov ​​​​tsw, xws li kub taub hau lossis lymphadenopathy vim qhov no yuav qhia tau tias muaj xwm txheej hnyav dua; Cov neeg mob yuav tsum tau qhia kom tsis txhob kho thiab nrhiav kev kho mob yog tias lawv tsim cov tsos mob lossis cov tsos mob ntawm anaphylaxis lossis angioedema.
- Cov neeg mob yuav tsum tau ntuas txog kev siv cawv sib xyaw; Cov neeg mob ntawm kev noj Horizant yuav tsum tau qhia kom tsis txhob haus cawv vim tias cawv yuav ua rau cov tshuaj tso tawm sai dua los ntawm nws cov ntsiav tshuaj txuas ntxiv.
-Cov neeg mob, tsev neeg, thiab cov neeg saib xyuas yuav tsum nkag siab tias cov tshuaj no tuaj yeem ua rau muaj kev nyuaj siab ua pa, tshwj xeeb tshaj yog rau cov neeg mob uas muaj kev ua pa tsis zoo thiab / lossis kev siv CNS depressants sib xyaw.
-Cov poj niam uas muaj peev xwm xeeb tub yuav tsum tham nrog lawv tus kws kho mob yog tias lawv dhau los lossis npaj siab yuav xeeb tub, thiab yog lawv npaj siab lossis pub niam mis.
-Cov neeg mob yuav tsum tau qhia kom tsis txhob tsav tsheb lossis ua haujlwm txaus ntshai kom txog thaum lawv tau txais kev paub txaus nrog cov tshuaj no kom nkag siab tias nws cuam tshuam li cas rau lawv lub hlwb thiab / lossis lub cev muaj zog.

Cov ntaub ntawv ntxiv

Nco ntsoov sab laj nrog koj tus kws kho mob kom paub meej tias cov ntaub ntawv uas tshwm sim hauv nplooj ntawv no siv tau rau koj tus kheej.