Gentizol tshuaj pleev

Nplooj ntawv no muaj cov ntaub ntawv ntawm Gentizol Ointment rau kev siv kws kho tsiaj .
Cov ntaub ntawv muab feem ntau suav nrog cov hauv qab no:
  • Gentizol Ointment Indications
  • Cov lus ceeb toom thiab ceeb toom rau Gentizol Ointment
  • Cov lus qhia thiab ntau npaum li cas rau Gentizol Ointment

Gentizol tshuaj pleev

Txoj kev kho no siv rau cov hom hauv qab no:
Lub tuam txhab: VetOne

(Gentamicin Sulfate, USP, Betamethasone Valerate, USP thiab Clotrimazole, USP)

ANADA #200-229, Pom zoo los ntawm FDA.



Kws kho tsiaj



Rau kev siv Otic hauv dev nkaus xwb

Gentizol Ointment Ceev faj

Tsoom Fwv Teb Chaws txoj cai txwv cov tshuaj no siv los ntawm lossis raws li kev txiav txim ntawm tus kws kho tsiaj muaj ntawv tso cai. Khaws qhov no thiab txhua yam tshuaj tawm ntawm qhov chaw me nyuam.



Kev piav qhia

Txhua gram ntawm Gentizol ™ tshuaj pleev muaj gentamicin sulfate USP sib npaug rau 3 mg gentamicin puag; betamethasone valerate, USP sib npaug rau 1 mg betamethasone; thiab 10 mg clotrimazole, USP nyob rau hauv ib tug ntxhia roj-raws li system uas muaj ib tug plasticized hydrocarbon gel.

Pharmacology

Gentamicin: Gentamicin sulfate yog ib qho tshuaj tua kab mob aminoglycoside tawm tsam ntau yam kab mob gram-negative thiab gram-positive kab mob. Hauv vitro Cov kev ntsuam xyuas tau txiav txim siab tias gentamicin yog cov kab mob bactericidal thiab ua los ntawm inhibiting ib txwm protein synthesis nyob rau hauv cov kab mob uas raug kab mob. Tshwj xeeb, gentamicin yog nquag tawm tsam cov kab mob hauv qab no feem ntau cais tawm ntawm pob ntseg canine: Staphylococcus aureus , lwm yam Staphylococcus spp., Pseudomonas aeruginosa , Proteus spp ,ua Escherichia coli .

Betamethasone: Betamethasone valerate yog ib qho hluavtaws adrenocorticoid rau kev siv tshuaj dermatologic. Betamethasone, ib qho analog ntawm prednisolone, muaj qib siab ntawm kev ua haujlwm corticosteroid thiab me ntsis ntawm cov haujlwm mineralocorticosteroid. Betamethasone valerate, 17-valerate ester ntawm betamethasone, tau pom tias muab cov tshuaj tiv thaiv kab mob thiab tiv thaiv kab mob hauv cov tshuaj tiv thaiv ntawm corticosteroid-responsive otitis externa. Cov tshuaj pleev corticosteroids tuaj yeem nqus tau los ntawm cov tawv nqaij tsis zoo. Inflammation tuaj yeem ua rau percutaneous nqus. Thaum nqus tau los ntawm daim tawv nqaij, tshuaj pleev corticosteroids raug tswj los ntawm txoj kev pharmacokinetic zoo ib yam li kev tswj hwm corticosteroids.



Clotrimazole: Clotrimazole yog ib tug dav-spectrum antifungal tus neeg sawv cev uas yog siv rau kev kho mob ntawm cov kab mob dermal tshwm sim los ntawm ntau hom kab mob dermatophytes thiab poov xab. Thawj qhov kev txiav txim ntawm clotrimazole yog tawm tsam kev faib thiab loj hlob kab mob.

Hauv vitro , clotrimazole nthuav tawm fungistatic thiab fungicidal kev ua haujlwm tawm tsam kev sib cais ntawm Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, Candida ua spp. thiab Malassezia pachydermatis (Pityrosporum canis) . Kev tiv thaiv rau clotrimazole yog qhov tsawg heev ntawm cov kab mob uas ua rau mycoses superficial. Nyob rau hauv induced otitis externa kis nrog Malassezia pachydermatis , 1% clotrimazole nyob rau hauv gentamicin-betamethasone-clotrimazole ointment tsheb yog siv tau ob qho tib si microbiologically thiab kho mob nyob rau hauv cov nqe lus ntawm txo cov exudate tsw thiab o.

Hauv cov kev tshawb fawb ntawm cov txheej txheem ntawm kev ua, qhov tsawg kawg nkaus fungicidal concentration ntawm clotrimazole ua rau kom cov phosphorus tebchaw intracellular mus rau hauv nruab nrab ambient nrog concomitant tawg ntawm cellular nucleic acids thiab accelerated poov tshuaj efflux. Cov xwm txheej no tau pib sai thiab dav tom qab ntxiv cov tshuaj. Clotrimazole yog absorbed tsis zoo tom qab daim ntawv thov dermal.

Gentamicin-Betamethasone-Clotrimazole: Los ntawm kev tsim txiaj ntawm nws peb cov khoom xyaw nquag, gentamicin-betamethasone-clotrimazole ointment muaj cov tshuaj tua kab mob, tiv thaiv kab mob, thiab tshuaj tua kab mob.

carbamazepine cov kev mob tshwm sim ntev

Hauv kev tshawb fawb txog kev ua tau zoo ntawm cov khoom siv, qhov sib xyaw ua ke thiab cov txiaj ntsig ntxiv ntawm txhua yam ntawm cov khoom tau pom. Hauv kev sim tshuaj, gentamicin-betamethasone-clotrimazole tau zoo hauv kev kho mob otitis externa cuam tshuam nrog cov kab mob thiab Malassezia pachydermatis . Gentamicin sulfate USP, Betamethasone valerate, USP thiab Clotrimazole, USP ointment txo qhov tsis xis nyob, liab, o, exudate, thiab tsw, thiab exerted ib tug muaj zog antimicrobial nyhuv.

Gentizol Ointment Indications

Gentizol ™ tshuaj pleev yog qhia rau kev kho mob ntawm canine mob thiab mob otitis externa txuam nrog poov xab. (Malassezia pachydermatis). , ua ntej Pityrosporum canis) thiab/lossis cov kab mob uas raug rau gentamicin.

Contraindications

Yog hais tias hypersensitivity rau ib yam ntawm cov Cheebtsam tshwm sim, kev kho mob yuav tsum tau txiav thiab tsim nyog kho mob instituted. Kev siv tshuaj sib xyaw ua ke uas paub tias yuav ua rau ototoxicity yuav tsum zam. Tsis txhob siv rau hauv cov dev uas paub txog perforation ntawm pob ntseg.

Ceeb toom

Kev siv gentamicin-betamethasone-clotrimazole ointment tau cuam tshuam nrog lag ntseg lossis tsis hnov ​​​​lus ib nrab ntawm cov dev me me (piv txwv li, geriatric). Qhov kev hnov ​​lus tsis txaus feem ntau yog ib ntus. Yog tias qhov hnov ​​​​lus lossis kev ua haujlwm ntawm lub vestibular tau muab sau tseg thaum lub sijhawm kho, tsis txhob siv cov tshuaj gentamicin-betamethasone-clotrimazole tam sim ntawd thiab yaug lub pob ntseg kom huv si nrog cov tshuaj uas tsis yog-ototoxic. Corticosteroids muab rau cov dev, luav, thiab nas thaum cev xeeb tub tau ua rau lub ntsej muag ntawm cov xeeb ntxwv. Lwm yam kev tsis sib haum xeeb xws li deformed forelegs, phocomelia, thiab anasarca tau tshaj tawm hauv cov xeeb ntxwv ntawm cov dev uas tau txais corticosteroids thaum cev xeeb tub.

Cov ntaub ntawv kho mob thiab kev sim tau pom tias cov tshuaj corticosteroids siv qhov ncauj lossis parenterally rau tsiaj txhu tuaj yeem ua rau thawj theem ntawm kev xeeb tub yog tias siv thaum lub sijhawm cev xeeb tub zaum kawg thiab tuaj yeem ua rau muaj menyuam ntxov ntxov tom qab dystocia, fetal tuag, khaws cia placenta thiab metritis.

Cov kev ceev faj

Kev txheeb xyuas cov kab mob yuav tsum tau ua los ntawm kev soj ntsuam xyuas cov kab mob me me los yog kab lis kev cai raws li qhov tsim nyog. Cov tshuaj tiv thaiv kab mob tsis zoo ntawm cov kab mob pathogenic yuav tsum tau txiav txim siab ua ntej siv qhov kev npaj no.

Yog tias muaj kab mob loj heev, cov kab mob fungi lossis cov poov xab tshwm sim, lossis yog tias muaj kev ntxhov siab, kev kho mob yuav tsum tau txiav thiab kho kom tsim nyog.

Kev tswj hwm ntawm cov koob tshuaj pom zoo ntawm Gentizol ™ tshuaj pleev dhau 7 hnub tuaj yeem ua rau qeeb qhov mob.

Tsis txhob noj. Cov tshuaj tiv thaiv tsis zoo tau raug pom tom qab kev noj ntawm qhov ncauj ntawm qee cov tshuaj corticosteroid npaj. Cov neeg mob yuav tsum tau ua tib zoo soj ntsuam rau cov cim ib txwm ntawm adrenocorticoid overdosage uas suav nrog sodium retention, poov tshuaj poob, dej tuav, hnyav nce, polydipsia thiab / lossis polyuria. Kev siv sijhawm ntev lossis kev siv tshuaj ntau dhau tuaj yeem ua rau muaj kev tiv thaiv kab mob tsis zoo.

Kev siv cov tshuaj corticosteroids, nyob ntawm qhov koob tshuaj, lub sijhawm, thiab cov tshuaj steroid tshwj xeeb, yuav ua rau cov tshuaj steroid endogenous inhibition tom qab tshem tawm cov tshuaj. Hauv cov neeg mob tam sim no tau txais lossis tsis ntev los no tshem tawm los ntawm kev kho corticosteroid, kev kho mob nrog corticosteroid sai sai yuav tsum tau txiav txim siab hauv cov xwm txheej tshwj xeeb.

Ua ntej instilling ib yam tshuaj rau hauv pob ntseg, tshuaj xyuas lub pob ntseg sab nraud kom huv si kom paub tseeb tias cov tympanic membrane tsis ruptured nyob rau hauv thiaj li yuav tiv thaiv tau kis tau tus kab mob mus rau nruab nrab pob ntseg thiab ua rau lub cochlea los yog vestibular apparatus los ntawm kev sib cuag ntev.

TOXICOLOGY: Cov kev tshawb fawb soj ntsuam thiab kev nyab xeeb nrog Gentamicin sulfate USP, Betamethasone valerate, USP thiab Clotrimazole, USP ointment tau qhia txog kev nyab xeeb dav dav ntawm qib pom zoo koob tshuaj hauv dev (saib CEEB TOOM/SIDE EFFECTS ).

Cov teebmeem

Gentamicin: Thaum aminoglycosides absorbed tsis zoo ntawm daim tawv nqaij, intoxication yuav tshwm sim thaum aminoglycosides siv tshuaj pleev ib ce rau lub sij hawm ntev mus rau lub qhov txhab loj, kub hnyiab, los yog tej tawv nqaij denuded, tshwj xeeb tshaj yog yog hais tias muaj lub raum insufficiency. Tag nrho cov aminoglycosides muaj peev xwm los tsim cov vestibular thiab irreversible vestibular, cochlear thiab raum toxicity.

Betamethasone: Cov kev mob tshwm sim xws li SAP thiab SGPT enzyme nce, poob phaus, anorexia, polydipsia, thiab polyuria tau tshwm sim tom qab siv parenteral lossis systemic synthetic corticosteroids hauv dev. ntuav thiab raws plab (qee zaus los ntshav) tau pom nyob rau hauv dev thiab miv. Cushing's Syndrome nyob rau hauv cov dev tau raug tshaj tawm nyob rau hauv koom nrog kev kho mob ntev lossis rov ua dua steroid.

Clotrimazole: Cov hauv qab no tau tshaj tawm qee zaus hauv tib neeg hauv kev sib txuas nrog kev siv clotrimazole: erythema, stinging, blistering, tev, edema, pruritus, urticaria, thiab khaus ntawm daim tawv nqaij tsis tshwm sim ua ntej kho.

Dosage thiab Administration

Lub pob ntseg sab nraud yuav tsum tau muab ntxuav kom huv thiab qhuav ua ntej kho. Tshem tawm cov khoom txawv teb chaws, khib nyiab, crusted exudates, thiab lwm yam, nrog rau cov kev daws teeb meem uas tsis yog khaus khaus. Cov plaub hau ntau dhau yuav tsum tau txiav tawm ntawm qhov chaw kho mob. Tom qab paub tseeb tias lub pob ntseg tsis zoo, ntxiv 4 tee (2 tee ntawm 215 g. fwj) ntawm Gentizol ™ tshuaj pleev ob zaug ib hnub rau hauv pob ntseg ntawm cov dev uas hnyav dua 30 lbs. Instill 8 tee (4 tee ntawm 215 g. lub raj mis) ob zaug ib hnub twg rau hauv lub pob ntseg ntawm cov dev uas hnyav 30 lbs. los yog ntau dua. Kev kho mob yuav tsum txuas ntxiv rau 7 hnub sib law liag.

Yuav Ua Li Cas

Gentizol ™ tshuaj pleev muaj nyob rau hauv 7.5 gram thiab 15 gram raj nrog rau hauv 10 gram, 15 gram, 25 gram thiab 215 gram yas fwj.

Khaws ntawm 2 ° thiab 25 ° C (36 ° thiab 77 ° F).

Co zoo ua ntej siv thaum siv lub raj mis 215 gram.

Manufactured rau: MWI Veterinary Supply, Boise, ID 83705

(888) 694-8381

www.vetone.net

Net Cov ntsiab lus:

NDC

7,5g 7

013985-006-75 ib

v1501006

10 g ib

013985-006-10

v1505006

15 g fwj

013985-006-45 ib

wb 1506006

15g cev

013985-006-15

V1 502006

25g ua

013985-006-25

wb 1503006

2 15g

013985-006-40 ib

wb 1504006

CPN: 13 150 112 ib

doxycycline hyclate 100 mg cap
FAT IB
Muab faib los ntawm MWI Animal Health

3041 W. PASADENA DR., BOISE, ID, 83705
Kev Pabcuam Cov Neeg Siv Khoom: 888-694-8381 ib
Hu dawb: 800-824-3703 Ib
Lub Vev Xaib: www.mwianimalhealth.com
www.vetone.net
Txhua qhov kev siv zog tau ua los xyuas kom meej qhov tseeb ntawm Gentizol Ointment cov ntaub ntawv luam tawm saum toj no. Txawm li cas los xij, nws tseem yog lub luag haujlwm ntawm cov neeg nyeem kom paub txog lawv tus kheej nrog cov ntaub ntawv cov khoom lag luam uas muaj nyob rau hauv US cov khoom lag luam daim ntawv lo lossis pob ntim.

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