Guillain-Barre Syndrome

Guillain-Barre Syndrome yog dab tsi?

Harvard Health Publishing

Guillain-Barré Syndrome yog ib qho kev tsis sib xws uas ua rau muaj kev puas tsuaj rau cov hlab ntsha peripheral. Cov hlab ntsha no xa cov lus los ntawm lub hlwb mus rau cov leeg, qhia cov leeg kom txav mus los. Lawv kuj nqa cov kev xav xws li mob ntawm lub cev mus rau lub hlwb. Cov hlab ntsha feem ntau ua rau cov leeg tsis muaj zog, feem ntau mus rau qhov tuag tes tuag taw, thiab tuaj yeem ua rau muaj teeb meem nrog kev hnov ​​​​lus, nrog rau qhov mob, tingling, 'crawling ntawm daim tawv nqaij' lossis qee qhov loog.



Guillain-Barré syndrome tuaj yeem dhau los ua kev kho mob xwm txheej ceev yog tias qhov tsis muaj zog cuam tshuam rau lub hauv siab cov leeg ua pa. Yog tias cov leeg hauv siab ua rau tuag tes tuag taw, tus neeg mob tuaj yeem tuag vim tsis muaj oxygen. Cov neeg uas muaj tus mob no yuav tsum tau ua tib zoo saib xyuas, feem ntau nyob hauv tsev kho mob, kom paub tseeb tias kev ua pa thiab lwm yam haujlwm tseem ceeb raug tswj xyuas.



Guillain-Barré syndrome yog ib yam kab mob autoimmune uas lub cev tiv thaiv kab mob tawm tsam thiab rhuav tshem cov myelin sheath, uas qhwv ib ncig ntawm cov hlab ntsha ntev lub cev zoo li rwb thaiv tsev nyob ib ncig ntawm cov yeeb nkab dej. Myelin tiv thaiv cov hlab ntsha thiab pab ua kom lub zog xa hluav taws xob ua rau lub paj hlwb. Yog tias cov myelin puas lawm, cov hlab ntsha impulses mus qeeb heev thiab tuaj yeem cuam tshuam. Yog tias cov leeg tsis tau txais kev txhawb nqa zoo los ntawm cov hlab ntsha, lawv yuav tsis ua haujlwm zoo.

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Qhov ua rau ntawm tus mob no tsis paub, tab sis ntau tus kws tshaj lij xav tias lub cev tiv thaiv kab mob sim tua cov kab mob sib kis (cov kab mob los yog tus kab mob) thiab ua rau raug mob paj hlwb hauv cov txheej txheem.



Guillain-Barré syndrome tsis tshua muaj tshwm sim, cuam tshuam tsawg dua 4,000 tus neeg hauv Tebchaws Meskas txhua xyoo. Vim li cas qhov kev tsis sib haum xeeb tshwm sim qee tus neeg yog qhov tsis paub. Hauv ntau tshaj li ob feem peb ntawm cov neeg mob, Guillain-Barré syndrome tshwm sim ib mus rau peb lub lis piam tom qab kis kab mob, suav nrog tus mob khaub thuas, mob khaub thuas, los yog kis kab mob tib neeg kev tiv thaiv kab mob (HIV), Epstein-Barr virus lossis cytomegalovirus. Qhov tshwm sim feem ntau tshwm sim zoo li yog kab mob kab mob nrog Campylobacter yog , uas ua rau mob plab hnyuv. Qee zaum, Guillain-Barré syndrome zoo li ua raws li kev txhaj tshuaj, phais lossis hloov pob txha pob txha. Kev tshawb fawb txog qhov ua rau Guillain-Barré syndrome tseem tab tom ua.

Cov tsos mob

Cov tsos mob ntawm Guillain-Barré syndrome txawv ntawm ib tus neeg mus rau ib tus neeg thiab tej zaum yuav mob me lossis hnyav. Feem ntau, thawj cov tsos mob pom tseeb yog qhov tsis muaj zog, thiab feem ntau qhov tsis muaj zog yog hnov ​​​​hauv ob txhais ceg. Sij hawm dhau mus, qhov tsis muaj zog feem ntau cuam tshuam nrog caj npab lossis lub taub hau, cuam tshuam qhov muag thiab lub taub hau txav thiab hais lus. Qee zaus, qhov tsis muaj zog yuav cuam tshuam rau caj npab lossis cov leeg ntawm lub taub hau ua ntej cuam tshuam rau ob txhais ceg.

Qee zaum qhov tsis muaj zog yog ua ntej lossis nrog kev hnov ​​​​ntawm tingling, feem ntau nyob rau hauv qis ob txhais ceg thiab ko taw. Nrog rau txhua pawg leeg cuam tshuam, kuj tuaj yeem mob thiab / lossis tingling. Guillain-Barré Syndrome tuaj yeem cuam tshuam lub cev tswj ntshav siab ib ntus, ua rau muaj ntshav siab txaus ntshai thaum tus neeg sawv cev tom qab pw lossis zaum.



Qhov kev tsis sib haum xeeb tau nce sai, nrog rau cov neeg mob feem ntau ntsib qhov tsis muaj zog tshaj plaws ntawm ob txhais ceg, caj npab, hauv siab thiab lwm cov leeg nqaij hauv peb lub lis piam tom qab pib tus kab mob. Qee zaum, qhov tsis muaj zog tuaj yeem ua rau mob sai heev. Thaum qhov no tshwm sim, qhov tsis muaj zog ntawm ob txhais ceg tuaj yeem ua tiav tag nrho ntawm ob txhais ceg, caj npab thiab cov leeg ntawm kev ua pa ntev li ob peb teev lossis ob peb hnub. Yog vim li ntawd, tus neeg uas muaj qhov tsis muaj zog tam sim ntawd ntawm ob txhais ceg lossis caj npab yuav tsum hu rau tus kws kho mob tam sim ntawd.

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Qhov tsis muaj zog yuav dhau hnub, lub lis piam lossis hli ua ntej qhov kev xav pib rov qab los. Rov qab mus rau qhov mob ua ntej lub zog thiab kev ua haujlwm tuaj yeem siv sijhawm ntau lub hlis lossis xyoo. Cov neeg mob feem ntau rov zoo li qub hauv lub hlis.

Kev kuaj mob

Guillain-Barré syndrome tuaj yeem nyuaj rau kev kuaj mob hauv nws cov theem ntxov tshaj plaws vim tias lwm yam kab mob tuaj yeem muaj cov tsos mob zoo sib xws, thiab vim tias cov tsos mob tshwm sim yuav txawv ntawm tus neeg mob mus rau tus neeg mob.

Koj tus kws kho mob yuav nug koj txog koj li keeb kwm kho mob thiab koj cov tsos mob.

Ob qhov kev sim yuav raug ua los pab koj tus kws kho mob txiav txim siab qhov kev kuaj mob:

hom tshuaj oxycodone
    Tus txha caj qaum- Hauv qhov kev sim no, ib rab koob muab tso rau hauv lub nraub qaum kom rub tawm qee cov kua cerebrospinal, cov kua uas nyob ib puag ncig tus txha caj qaum thiab lub hlwb. Cov kua cerebrospinal ntawm cov neeg uas muaj tus mob Guillain-Barré feem ntau muaj cov protein ntau dua li qub. Nerve conduction velocity test- Hauv qhov kev sim no, cov hlau me me hu ua electrodes tau muab tso rau ntawm daim tawv nqaij hla cov hlab ntsha los kuaj. Ib qho hluav taws xob impulse yog pub los ntawm ib qho electrode muab tso rau sab sauv ntawm cov hlab ntsha thiab khaws los ntawm lwm cov electrodes muab tso rau hauv qis ntawm cov hlab ntsha. Qhov kev ntsuas ntsuas sai npaum li cas cov hluav taws xob impulse txav mus rau hauv cov hlab ntsha los ntawm cov hluav taws xob sab saud mus rau cov hluav taws xob qis. Cov paj hlwb cuam tshuam los ntawm kev tsis sib haum xeeb yuav ua cov cim qeeb dua li cov hlab ntsha uas tsis muaj kev cuam tshuam.

Lub sijhawm xav tau

Tsis muaj txoj hauv kev los twv seb Guillain-Barré syndrome yuav kav ntev npaum li cas. Cov tsos mob feem ntau ncav cuag lawv qhov siab tshaj plaws li ntawm peb lub lim tiam ntawm qhov teeb meem. Cov tsos mob tuaj yeem nyob ntawm theem ntawd rau hnub, lis piam lossis hli, thiab tom qab ntawd maj mam zoo dua. Lub zog maj mam rov qab los. Nws tsuas yog siv ob peb lub lis piam lossis ntev li peb xyoos. Cov neeg feem coob rov zoo tag nrho hauv ob peb lub hlis, tab sis qee tus yeej tsis tau txais lub zog tag nrho thiab yuav xav tau kev phais, kho lub cev los yog cov cuab yeej orthopedic los kho cov teeb meem lossis cob qhia lub cev kom haum.

Kev tiv thaiv

Vim tsis muaj leej twg paub dab tsi ua rau Guillain-Barré syndrome, tsis muaj txoj hauv kev los tiv thaiv nws.

Kev kho mob

Feem ntau cov neeg mob uas muaj Guillain-Barré syndrome tau pw hauv tsev kho mob, vim tias qhov mob tuaj yeem ua rau cov leeg hauv siab tsis muaj zog mus rau qhov uas ua rau ua pa nyuaj lossis ua tsis tau. Hauv tsev kho mob, cov neeg mob tuaj yeem saib xyuas thiab muab lub tshuab ua pa, yog tias tsim nyog. Yog tias tus mob Guillain-Barré ua rau tuag tes tuag taw ntawm ceg lossis caj npab, tus neeg mob yuav xav tau kev pab cuam ntawm kev ua neej nyob txhua hnub xws li noj mov thiab tshem tawm cov khoom pov tseg. Kev saib xyuas kev ua haujlwm ntawm lub plawv thiab ntshav siab thiab lwm yam kev txhawb nqa (xws li kev txhawb nqa lub hlwb, kev tswj qhov mob, kev tu tawv nqaij, kev tiv thaiv cov ntshav txhaws, thiab kev kho lub cev) kuj tseem ceeb.

Ob txoj kev kho mob tau pom tias txo qis qhov mob ntawm Guillain-Barré syndrome thiab kev rov qab sai:

    Plasmapheresis (los yog plasma exchange)yog ib qho txheej txheem uas cov ntshav raug tshem tawm ntawm tus neeg mob, thiab tom qab ntawd sib cais rau hauv plasma (cov kua dej ntawm cov ntshav) thiab cov qe ntshav. Cov qe ntshav tom qab ntawd muab tso rau hauv lub cev. Lub cev tsim cov plasma ntau dua los tsim cov khoom uas raug tshem tawm. Tsis muaj leej twg paub vim li cas qhov kev kho mob no ua haujlwm, tab sis feem ntau cov kws tshawb fawb ntseeg tias plasmapheresis tshem tawm cov tshuaj uas ua rau lub cev tiv thaiv kab mob tawm tsam cov hlab ntsha peripheral. Infusions ntawm immunoglobulin, kev sib xyaw ntawm cov tshuaj tiv thaiv kab mob uas tsim tawm los ntawm lub cev tiv thaiv kab mob. Cov koob tshuaj ntau ntawm immunoglobulin tuaj yeem ua haujlwm los ntawm kev thaiv cov tshuaj tiv thaiv kab mob uas tuaj yeem ua rau muaj kev cuam tshuam.

Ob hom kev kho mob no suav hais tias muaj txiaj ntsig zoo sib xws; qhov kev xaiv ntawm kev kho mob feem ntau yog txiav txim los ntawm yam xws li kev kho mob thiab cov neeg mob nyiam. IVIG feem ntau xaiv vim nws yooj yim ntawm kev tswj hwm. Lwm yam kev kho mob rau Guillain-Barré syndrome tab tom tshawb nrhiav.

Tom qab tau pib rov zoo lawm, cov neeg mob yuav xav tau kev kho lub cev los pab lawv rov muaj zog thiab txav tau zoo.

qhov kev faib tawm ntawm cov tshuaj yog tramadol

Thaum Hu Rau Tus Kws Tshaj Lij

Hu rau tus kws kho mob tam sim ntawd yog tias koj muaj kev qaug zog ntawm koj ob txhais ceg, caj npab los yog cov leeg ntawm koj lub taub hau uas hnyav dua li ob peb teev lossis hnub.

Kev kwv yees

Kev saib mus ntev rau Guillain-Barré syndrome feem ntau yog qhov zoo. Cov neeg mob feem ntau rov zoo tag nrho, txawm hais tias nws tuaj yeem siv sijhawm ntau lub hlis lossis xyoo kom rov muaj zog ua ntej muaj mob thiab txav mus los. Kwv yees li 30% ntawm cov neeg mob tseem muaj qee qhov tsis muaj zog peb xyoos tom qab tus kab mob tawm tsam. Kwv yees li 3% ntawm cov neeg mob muaj qaug zog thiab tingling rov qab xyoo tom qab. Kwv yees li 3% mus rau 5% tuag, yuav luag txhua lub sijhawm vim lawv ua rau tuag tes tuag taw ntawm cov leeg hauv siab ua ntej lawv mus txog tsev kho mob.

Cov peev txheej sab nraud

National Institute of Neurological Disorders thiab Stroke
http://www.ninds.nih.gov/

American Academy ntawm Neurology (AAN)
http://www.aan.com/

Cov ntaub ntawv ntxiv

Nco ntsoov sab laj nrog koj tus kws kho mob kom paub tseeb tias cov ntaub ntawv uas tshwm sim hauv nplooj ntawv no siv tau rau koj tus kheej.