Ibuprofen Side Effects

Hauv Summary

Feem ntau tshaj tawm cov kev mob tshwm sim ntawm ibuprofen muaj xws li: hemorrhage, ntuav, anemia, txo hemoglobin, eosinophilia, thiab kub siab. Lwm cov kev mob tshwm sim muaj xws li: Upper gastrointestinal hemorrhage, lub plab hnyuv plab ulcer, kiv taub hau, thiab dyspepsia. Saib hauv qab no kom paub cov npe ntawm cov teebmeem tsis zoo.

Rau Cov Neeg Siv Khoom

Siv rau ibuprofen : Lub qhov ncauj capsule kua puv, qhov ncauj ncua kev kawm ntawv, qhov ncauj ntsiav tshuaj, qhov ncauj ntsiav tshuaj chewable

Lwm hom tshuaj noj:

• txhaj tshuaj

Ceeb toom

Txoj kev ntawm qhov ncauj (Tablet; Ncua tseg; Capsule, Kua Filled; Tablet, Chewable)

NSAIDs Tej zaum yuav ua rau muaj kev pheej hmoo siab ntawm cov kab mob plawv thrombotic, myocardial infarction, thiab mob stroke, uas tuaj yeem ua rau tuag taus. Qhov kev pheej hmoo no tuaj yeem nce ntxiv rau cov neeg mob uas muaj kab mob plawv lossis muaj feem cuam tshuam rau cov kab mob plawv. Ibuprofen yog contraindicated rau kev kho mob ntawm peri-operative mob nyob rau hauv qhov chaw ntawm coronary artery bypass graft (CABG) phais. NSAIDs tseem tuaj yeem ua rau muaj kev pheej hmoo ntau ntxiv ntawm kev mob plab hnyuv loj tshwj xeeb tshaj yog nyob rau hauv cov neeg laus, suav nrog los ntshav, ulceration, thiab perforation ntawm lub plab lossis cov hnyuv, uas tuaj yeem ua rau tuag taus.

Kev mob tshwm sim yuav tsum tau mus kho mob tam sim

Nrog rau nws cov teebmeem xav tau, ibuprofen tuaj yeem ua rau qee qhov tsis xav tau. Txawm hais tias tsis yog tag nrho cov kev mob tshwm sim no tuaj yeem tshwm sim, yog tias lawv tshwm sim lawv yuav xav tau kev kho mob.

Nrog koj tus kws kho mob tham tam sim ntawd Yog tias ib qho ntawm cov kev mob tshwm sim hauv qab no tshwm sim thaum noj ibuprofen:

Feem ntau

• Mob plab
• acid los yog qaub plab
• belching
• mob plab
• huab tso zis
• txo cov zis
• txo cov zis tso zis los yog txo cov zis-concentrating peev xwm
• raws plab
• teeb meem plab hnyuv (stool)
• cua lossis roj ntau dhau hauv plab lossis hnyuv
• tag kev cia siab
• mob plawv
• plab zom mov
• khaus tawv nqaij
• mob lossis tsis xis nyob hauv siab, plab, lossis caj pas
• tawv nqaij tawv
• dhau gas
• xeev siab
• nrov nrov, rattling ua pa
• ua pob khaus nrog cov kab mob tiaj tus los yog cov kab mob me me ntawm daim tawv nqaij
• ua tsis taus pa
• o ntawm lub ntsej muag, ntiv tes, tes, taw, sab ceg, lossis pob taws
• ua tsis taus pa thaum so
• ua pa nyuaj nrog kev tawm dag zog
• los ntshav los yog bruising txawv txawv
• nkees nkees lossis qaug zog
• ntuav
• hnyav nce

Tsawg dua

• Mob plab
• plab mob los yog tsis xis nyob

Tsis tshua muaj

• Kev ntxhov siab
• nraub qaum, ceg, lossis mob plab
• cov pos hniav los ntshav
• blistering, peeling, loosening ntawm daim tawv nqaij
• ntshav hauv cov zis los yog quav
• ntshav, dub, los yog quav quav
• qhov muag tsis pom kev
• kub hnyiab hauv siab los yog plab
• hloov tsis pom kev
• mob hauv siab
• txias
• av nplaum cov quav
• nrog rau
• tsis meej pem
• cem quav
• hnoos los yog hoarseness
• tso zis tsaus
• txo cov zis tso zis
• kev nyuaj siab
• ua pa nyuaj
• nyuaj nqos
• dilated caj dab veins
• kiv taub hau
• qhov ncauj qhuav
• qaug zog heev
• nrawm, tsis xwm yeem, pounding, lossis sib tw lub plawv dhia lossis mem tes
• ua npaws nrog los yog tsis txias
• tso zis ntau zaus
• lub cev o
• kev xav ntawm nkees lossis qaug zog
• plaub hau poob , thinning ntawm cov plaub hau
• mob taub hau
• khaus khaus los yog cov welts
• kev ua phem
• tsis pom kev
• nce ntshav siab
• nce ntim ntawm daj ntseg, dilute zis
• ua tsis taus pa
• chim siab
• khaus
• pob qij txha los yog mob leeg
• lab cov txiaj ntsig uas qhia txog teeb meem nrog lub siab
• qaug zog
• cov quav daj
• poob qab los noj mov
• sab nraub qaum lossis sab mob
• leeg twitch
• ntshav ntswg
• mob los yog tso zis nyuaj
• mob hauv plab, sab, lossis plab, tejzaum nws tawg mus rau sab nraub qaum
• pinpoint liab me ntsis ntawm daim tawv nqaij
• puffiness los yog o ntawm daim tawv muag los yog ib ncig ntawm lub qhov muag, ntsej muag, daim di ncauj, los yog tus nplaig
• ua pob liab liab
• liab ntawm daim tawv nqaij, feem ntau nrog ib tug liab doog chaw
• liab, khaus qhov muag
• liab ntawm daim tawv nqaij
• qaug dab peg
• mob plab heev, cramping, kub hnyiab
• mob hnyav thiab xeev siab txuas ntxiv
• mob caj pas
• mob, rwj, los yog pob dawb ntawm qhov ncauj los yog ntawm daim di ncauj
• txha caj dab los yog rov qab
• plab chim
• ntxhov siab
• o lossis mob qog
• tenderness nyob rau hauv plab cheeb tsam
• nqhis dej
• nruj hauv siab
• tsis kaj siab ua tsis taus pa tsw
• sab xis sab xis mob plab
• ntuav ntshav
• ntuav ntawm cov khoom uas zoo li kas fes hauv av
• hawb pob
• daj qhov muag thiab tawv nqaij

Cov tsos mob ntawm overdose

• Blueish daim di ncauj los yog daim tawv nqaij
• nyuaj pw
• disorientation
• kiv taub hau, faintness, los yog lightheadedness thaum sawv los ntawm ib qho chaw pw los yog zaum tam sim ntawd
• tsaug zog mus rau qhov coma
• kev xav tsis thoob
• lightheadedness lossis fainting
• mus ob peb vas los yog lwm yam kev puas siab puas ntsws hloov
• nqaij tshis
• tsis ua pa
• ceev, ua pa tob
• kev ntxhov siab
• qeeb los yog lub plawv dhia tsis xwm yeem
• mob plab
• sudden ntog
• tawm hws

Kev mob tshwm sim tsis tas yuav tsum tau kho mob tam sim

Qee qhov kev mob tshwm sim ntawm ibuprofen tuaj yeem tshwm sim uas feem ntau tsis xav tau kev kho mob . Cov kev mob tshwm sim no yuav ploj mus thaum kho raws li koj lub cev hloov kho rau cov tshuaj. Tsis tas li ntawd, koj tus kws kho mob yuav tuaj yeem qhia koj txog txoj hauv kev los tiv thaiv lossis txo qee qhov kev mob tshwm sim.

Tshawb xyuas nrog koj tus kws kho mob yog tias muaj cov kev mob tshwm sim hauv qab no txuas ntxiv los yog thab plaub los yog koj muaj lus nug txog lawv:

Feem ntau

• Txuas ntxiv suab nrov lossis buzzing lossis lwm yam suab nrov uas tsis tau piav qhia hauv pob ntseg
• tsis hnov ​​lus
• ntxhov siab

Tsis tshua muaj

• quaj
• depersonalization
• kev poob siab
• qhov muag qhuav
• dysphoria
• kev zoo siab
• xav tu siab los tsis muaj
• tsis qab los noj mov
• tsis txaus siab lossis txaus siab
• kev nyuaj siab
• paranoia
• ceev los teb los yog overreact
• hloov siab sai sai
• kua ntswg
• pw tsaug zog los yog pw tsaug zog txawv txawv
• pw tsis tsaug zog
• txham
• qhov ntswg
• teeb meem tsom
• teeb meem pw tsaug zog
• pw tsis taus

Rau Cov Kws Kho Mob

Siv rau ibuprofen: compounding hmoov, intravenous tov, qhov ncauj capsule, qhov ncauj ncua kev kawm ntawv, qhov ncauj ntsiav tshuaj, qhov ncauj ntsiav tshuaj chewable

General

Feem ntau tshaj tawm cov teebmeem tshwm sim yog plab hnyuv (GI) hauv qhov xwm txheej thiab suav nrog xeev siab, ntuav, flatulence , thiab raws plab.

Rau Patent Ductus Arteriosus hauv Pediatric Patients:

plab hnyuv

Feem ntau (10% lossis ntau dua): xeev siab (txog 57%), ntuav (txog 22%), flatulence (txog 16%), raws plab (txog 10%)

Feem ntau (1% mus rau 10%): Dyspepsia mob plab, mob epigastric, kub hnyiab, mob plab, plab zom mov, cem quav, plab cramps / mob, tag nrho ntawm GI ib ntsuj av, tsam plab, GI hemorrhage, melena

Tsis tshua muaj (0.1% mus rau 1%): mob plab, dyspepsia, mob plab

Tsawg heev (tsawg dua 0.01%): peptic ulcer, perforation, hematemesis, qhov ncauj ulceration, exacerbation ntawm mob plab , exacerbation ntawm Crohn tus kab mob

Zaus tsis qhia : Lub ncauj qhuav, duodenitis , esophagitis mob plab ulcer, duodenal rwj GI ntshav, glossitis, qhov quav los ntshav , stomatitis , eructation gingival rwj, pancreatitis

Rau Patent Ductus Arteriosus hauv Pediatric Patients:

Feem ntau (10% lossis ntau dua): GI mob tsis yog-necrotizing enterocolitis (22%)

Feem ntau (1% mus rau 10%): Necrotizing enterocolitis, plab hnyuv perforation

Zaus tsis qhia : Mob plab , kab mob gastroesophageal reflux mob plab, ileus , inguinal hernia

Postmarketing qhia : GI perforation^{[ Ref ]}

Mob plawv

Feem ntau (10% lossis ntau dua): Hemorrhage (txog 10%), kub siab (10%), hypotension (10%)

Tsawg heev (tsawg dua 0.01%): Mob plawv tsis ua hauj lwm

Zaus tsis qhia : Congestive plawv tsis ua hauj lwm , tachycardia , arrhythmia mob myocardial infarction, palpitations , vasculitis , sinus bradycardia , mob angina pectoris , cov xwm txheej thrombotic

Rau Patent Ductus Arteriosus hauv Pediatric Patients:

Zaus tsis qhia : tachycardia, plawv tsis ua hauj lwm, hypotension^{[ Ref ]}

Lub paj hlwb

Feem ntau (10% lossis ntau dua): Mob taub hau (txog 12%)

Feem ntau (1% mus rau 10%): kiv taub hau, ntxhov siab vim

Tsawg heev (tsawg dua 0.01%): Cerebrovascular kev huam yuaj

Zaus tsis qhia : Syncope qaug zog, paresthesia, somnolence, tremors, convulsions, coma

Rau Patent Ductus Arteriosus hauv Pediatric Patients:

Feem ntau (1% mus rau 10%): Intraventricular hemorrhage, periventricular hemorrhage

Zaus tsis qhia : Convulsions^{[ Ref ]}

Lub raum

Tsawg heev (tsawg dua 0.01%): mob raum tsis ua haujlwm, lub raum papillary necrosis, interstitial nephritis, nephrotic syndrome lub raum tsis ua haujlwm, lub raum tsis ua haujlwm

Zaus tsis qhia : Cystitis azotemia, creatinine tshem tawm txo, glomeruliitis, tubular necrosis, nephrotoxicity

Rau Patent Ductus Arteriosus hauv Pediatric Patients:

Feem ntau (10% lossis ntau dua): Cov xwm txheej rau lub raum (21%)

Tsis tshua muaj (0.1% rau 1%): mob raum tsis ua haujlwm^{[ Ref ]}

Tus naj npawb ntawm tag nrho cov xwm txheej hauv lub raum hauv cov menyuam mos tsis pub dhau 30 hnub ntawm kev kho mob tom qab siv IV yog 21% thiab suav nrog cov ntshav urea (7%), lub raum tsis ua haujlwm / tsis zoo (6%), txo cov zis tso zis (3%), nce ntshav creatinine. (3%), lub raum tsis ua haujlwm (1%), thiab nce ntshav urea nrog hematuria (ib%).^{[ Ref ]}

Hematology

Qhov tshwm sim ntawm tag nrho cov txheej xwm los ntshav nyob rau hauv 30 hnub ntawm kev kho mob nrog IV siv nyob rau hauv cov me nyuam mos yug ntxov ntxov yog 32%. Qhov feem pua ​​no suav nrog qib 1 thiab 2 intraventricular hemorrhage (15%), qib 3 thiab 4 intraventricular hemorrhage (15%), thiab lwm yam los ntshav (6%).^{[ Ref ]}

Feem ntau (10% los yog ntau tshaj): Anemia (txog 36%), eosinophilia (txog 26%), neutropenia (txog 13%), thrombocythemia (txog 10%)

Feem ntau (1% mus rau 10%): hemoglobin txo qis

Tsawg heev (tsawg dua 0.01%): Leukopenia, thrombocytopenia , agranulocytosis , hemolytic anemia , aplastic anemia , pancytopenia , hematocrit txo

xiav percocet alv 196

Zaus tsis qhia : lymphadenopathy , los ntshav ntu

Rau Patent Ductus Arteriosus hauv Pediatric Patients:

Feem ntau (10% los yog ntau tshaj): Anemia (32%), tag nrho los ntshav (32%), intraventricular hemorrhage (29%), Neutropenia, thrombocytopenia^{[ Ref ]}

Dermatology

Feem ntau (1% mus rau 10%): pob khaus, maculopapular pob, pruritus

Tsawg heev (tsawg dua 0.01%): Stevens-Johnson Syndrome , erythema multiforme, tshuaj lom epidermal necrolysis

Zaus tsis qhia : ecchymosis, ntshav liab alopecia tawm hws, photosensitivity, angioedema , exfoliative dermatitis, urticaria , vesiculobullous eruptions, Henoch Schonlein vasculitis

Rau Patent Ductus Arteriosus hauv Pediatric Patients:

Feem ntau (10% lossis ntau dua): Cov tawv nqaij tawv nqaij / khaus (16%)^{[ Ref ]}

Metabolic

Feem ntau (10% lossis ntau dua): Hypokalemia (txog 19%), hypoproteinemia (txog 13%), ntshav urea nce (10%), hypernatremia (10%), hypoalbuminemia (10%)

Feem ntau (1% mus rau 10%): qab los noj mov, dej tuav

Zaus tsis qhia : Kev hloov pauv qab los noj mov, hyperglycemia, cov tshuaj tiv thaiv hypoglycemic, acidosis

Rau Patent Ductus Arteriosus hauv Pediatric Patients:

Feem ntau (10% lossis ntau dua): Hypoglycemia (12%), hypocalcemia (12%), ntshav creatinine nce, ntshav sodium txo

Feem ntau (1% mus rau 10%): Hypernatremia

Zaus tsis qhia : Zaub mov muaj teeb meem, hyperglycemia^{[ Ref ]}

Lwm yam

Feem ntau (10% lossis ntau dua): Bacteremia (13%), ntshav LDH nce (txog 10%)

Feem ntau (1% mus rau 10%): Peripheral edema mob hemorrhage, tinnitus , hnov ​​tsis hnov ​​lus, edema, qaug zog

Tsawg heev (tsawg dua 0.01%): Aseptic meningitis , vertigo , exacerbation ntawm tus kab mob cuam tshuam nrog o

Zaus tsis qhia : Ua npaws, kab mob, sepsis, hnyav hloov, asthenia, malaise, pseudo-mob, hnov ​​tsis hnov, tsaug zog

Rau Patent Ductus Arteriosus hauv Pediatric Patients:

Feem ntau (10% lossis ntau dua): Sepsis (43%)

Feem ntau (1% mus rau 10%): edema, kua retention

Zaus tsis qhia : Ntau yam kab mob^{[ Ref ]}

Ua pa

Feem ntau (10% lossis ntau dua): Cov kab mob mob ntsws o (txog 10%)

Feem ntau (1% mus rau 10%): hnoos

Tsawg heev (tsawg dua 0.01%): Mob hawb pob bronchospasm, ua tsis taus pa , hawb

Zaus tsis qhia : Apnea, ua pa nyuaj siab , pneumonia, rhinitis, epistaxis

Rau Patent Ductus Arteriosus hauv Pediatric Patients:

Feem ntau (10% lossis ntau dua): Apnea (28%), mob ua pa (19%), ua pa tsis ua haujlwm (10%), bronchopulmonary dysplasia

Feem ntau (1% mus rau 10%): Atelectasis, pulmonary hemorrhage

Tsis tshua muaj (0.1% mus rau 1%): Hypoxemia

Postmarketing qhia : Pulmonary hypertension ^{[ Ref ]}

Mob siab

Tsawg heev (tsawg dua 0.01%): Kab mob siab, daj daj

Zaus tsis qhia : Hepatorenal syndrome, daim siab necrosis, daim siab tsis ua haujlwm, txawv txav kuaj lub siab ua haujlwm

Rau Patent Ductus Arteriosus hauv Pediatric Patients:

Zaus tsis qhia : Cholestasis, jaundice^{[ Ref ]}

Mob siab heev

Cov tshuaj tiv thaiv hypersensitivity tau raug tshaj tawm thiab tej zaum yuav muaj xws li ib qho ntawm cov hauv qab no: ib qho mob plab, ua npaws, ua daus no, xeev siab, ntuav, thiab anaphylaxis ; Cov kab mob ua pa reactivity muaj xws li bronchospasm, hawb pob / mob hawb pob, lossis ua tsis taus pa; Cov tshuaj tiv thaiv ntawm daim tawv nqaij, uas tsis tshua muaj xws li exfoliative thiab bullous dermatoses, Stevens-Johnson syndrome, toxic epidermal necrolysis, angioedema, pruritus, thiab urticaria.^{[ Ref ]}

Zaus tsis qhia : Cov tshuaj tiv thaiv anaphylactoid, cov tshuaj tiv thaiv hypersensitivity^{[ Ref ]}

Ocular

Tsawg heev (tsawg dua 0.01%): Pom kev cuam tshuam

Zaus tsis qhia pom tsis pom kev, amblyopia, tsis pom kev, scotomata, hloov xim tsis pom kev, conjunctivitis qhov muag qhuav, diplopia, optic neuritis , cataracts, kho qhov muag neuritis , toxic optic neuropathy^{[ Ref ]}

Musculoskeletal

Zaus tsis qhia : Lupus erythematosus syndrome^{[ Ref ]}

Kev puas siab puas ntsws

Zaus tsis qhia : Kev ntxhov siab , tsis meej pem, kev nyuaj siab, npau suav txawv txav, insomnia , kev xav lability, hallucinations^{[ Ref ]}

Cov kab mob genitourinary

Feem ntau (1% mus rau 10%): tso zis tso quav

Tsawg heev (tsawg dua 0.01%): Proteinuria, hematuria

Zaus tsis qhia : Dysuria polyuria, oliguria, menorrhagia

Rau Patent Ductus Arteriosus hauv Pediatric Patients:

Feem ntau (10% lossis ntau dua): Oliguria, hematuria

Feem ntau (1% mus rau 10%): Cov kab mob tso zis^{[ Ref ]}

Immunologic

Zaus tsis qhia : Ntshav Qab Zib^{[ Ref ]}

Hauv zos

Feem ntau (1% mus rau 10%): Infusion site mob

Postmarketing qhia : Kev hnov ​​​​ntxhiab ntawm qhov ncauj / caj pas

Rau Patent Ductus Arteriosus hauv Pediatric Patients:

Zaus tsis qhia : Qhov chaw txhaj tshuaj tiv thaiv^{[ Ref ]}

Endocrine

Zaus tsis qhia Cov tsos mob: Gynecomastia

Rau Patent Ductus Arteriosus hauv Pediatric Patients:

Feem ntau (1% mus rau 10%): Adrenal tsis txaus ^{[ Ref ]}

Cov ntaub ntawv

1. Cerner Multum, Inc. 'Australian Product Information.' O 0

2. 'Cov ntaub ntawv khoom. Caldolor (ibuprofen). Cumberland Pharmaceuticals Inc, Nashville, TN.

3. 'Cov ntaub ntawv khoom. Motrin (ibuprofen). Pharmacia and Upjohn, Kalamazoo, MI.

4. Cerner Multum, Inc. 'UK Summary of Product Characteristics.' O 0

5. 'Cov ntaub ntawv khoom. NeoProfen (ibuprofen). Ovation Pharmaceuticals Inc, Deerfield, IL.

6. 'Cov ntaub ntawv khoom. Ibuprofen (ibuprofen). Par Pharmaceutical Inc, Spring Valley, NY.

Cov ntaub ntawv ntxiv

Nco ntsoov sab laj nrog koj tus kws kho mob kom paub meej tias cov ntaub ntawv uas tshwm sim hauv nplooj ntawv no siv tau rau koj tus kheej.

Qee qhov kev mob tshwm sim yuav tsis qhia. Koj tuaj yeem qhia lawv mus rau lub FDA .