Lisinopril Dosage

Siv rau cov hauv qab no muaj zog: 2.5 mg; 5 mg; 10 mg; 20 mg; 40 mg; 30 mg; 1 mg/ml

Ib txwm Adult Dose rau:

Ib txwm Geriatric Dose rau:

Ib txwm Pediatric Dose rau:

Cov lus qhia txog kev noj tshuaj ntxiv:

Ib txwm siv rau cov neeg laus noj ntshav siab

Thawj koob tshuaj: 10 mg ntawm qhov ncauj ib hnub ib zaug; 5 mg ntawm qhov ncauj ib hnub ib zaug
Cov koob tshuaj kho mob: 20 mus rau 40 mg ntawm qhov ncauj ib hnub ib zaug
Cov koob tshuaj ntau tshaj: 80 mg ntawm qhov ncauj ib hnub ib zaug

Cov lus pom :
-Cov koob tshuaj thawj zaug yog 5 mg ntawm qhov ncauj ib hnub ib zaug hauv cov neeg mob uas tau txais diuretic.
-Cov koob tshuaj 80 mg yog siv tab sis tsis tshwm sim kom muaj txiaj ntsig zoo dua.
-Yog tias tsis tswj ntshav siab nrog lisinopril ib leeg, cov tshuaj diuretic qis tuaj yeem raug ntxiv (piv txwv li, hydrochlorothiazide, 12.5 mg). Tom qab ntxiv cov tshuaj diuretic, nws tuaj yeem txo qhov koob tshuaj lisinopril.



Ib txwm siv rau cov neeg laus noj rau Congestive Heart Failure

Thawj koob tshuaj: 2.5 mus rau 5 mg ntawm qhov ncauj ib hnub ib zaug
Kev Kho Kom Zoo: Cov koob tshuaj yuav tsum tau nce ntxiv raws li kev zam
Cov koob tshuaj ntau tshaj: 40 mg ntawm qhov ncauj ib hnub ib zaug

Cov lus pom :
-Cov koob tshuaj diuretic yuav tsum tau hloov kho kom txo qis hypovolemia, uas tuaj yeem ua rau hypotension. Cov tsos mob ntawm hypotension tom qab thawj zaug koob tshuaj lisinopril tsis txwv cov koob tshuaj titration tom ntej nrog cov tshuaj.

Ib txwm siv rau cov neeg laus noj rau Myocardial Infarction

Thawj koob tshuaj: 5 mg ntawm qhov ncauj (hauv 24 teev tom qab pib mob myocardial infarction)
Cov koob tshuaj tom ntej: 5 mg ntawm qhov ncauj tom qab 24 teev, tom qab ntawd 10 mg ntawm qhov ncauj tom qab 48 teev.
Cov koob tshuaj tu: 10 mg ntawm qhov ncauj ib hnub ib zaug. Kev noj tshuaj yuav tsum txuas ntxiv mus ntev li 6 lub lis piam.

Cov lus pom :
- Kev kho mob yuav tsum pib ntawm 2.5 mg rau cov neeg mob uas muaj ntshav siab systolic (tsawg dua lossis sib npaug li 120 mm Hg thiab ntau dua 100 mmHg) hauv thawj 3 hnub tom qab infarct. Yog tias lub sijhawm ntev hypotension tshwm sim (systolic ntshav siab tsawg dua 90 mmHg rau ntau tshaj 1 teev) kev kho yuav tsum tau muab tshem tawm.

Kev siv: Txo cov neeg tuag nyob rau hauv mob myocardial infarction

Ib txwm siv rau cov neeg laus koob tshuaj rau ntshav qab zib nephropathy

Thawj koob tshuaj: 10 mus rau 20 mg ntawm qhov ncauj ib hnub ib zaug
Cov koob tshuaj kho mob: 20 mus rau 40 mg ntawm qhov ncauj ib hnub ib zaug
Kev noj tshuaj tuaj yeem raug titrated nce siab txhua 3 hnub

Cov lus pom :
-Tsis pom zoo qhia.

Ib txwm Geriatric Dose rau Ntshav Qab Zib

Thawj koob tshuaj: 2.5 mus rau 5 mg ntawm qhov ncauj ib hnub ib zaug
Cov koob tshuaj tu: Cov koob tshuaj yuav tsum tau nce ntxiv ntawm 2.5 mg rau 5 mg ib hnub twg ntawm 1 mus rau 2 lub lis piam.
Cov koob tshuaj ntau tshaj: 40 mg ntawm qhov ncauj ib hnub ib zaug

Ib txwm Pediatric Dose for Hypertension

Cov neeg mob me dua lossis sib npaug li 6 xyoo :
Cov koob tshuaj pib: 0.07 mg / kg ntawm qhov ncauj ib hnub ib zaug (qhov siab tshaj plaws thawj zaug yog 5 mg ib hnub ib zaug)
Kev Kho Mob: Kev noj tshuaj yuav tsum tau hloov kho raws li cov ntshav siab teb ntawm 1 mus rau 2 lub lis piam ib ntus.
Cov koob tshuaj ntau tshaj: Cov koob tshuaj ntau dua 0.61 mg / kg lossis ntau dua 40 mg tsis tau kawm hauv cov neeg mob menyuam yaus

Cov lus pom :
-Cov tshuaj no tsis pom zoo rau cov neeg mob menyuam yaus hnub nyoog qis dua 6 xyoos lossis hauv cov neeg mob menyuam yaus uas muaj glomerular filtration rate tsawg dua 30 mL / min.

Renal Dose Adjustments

CrCl ntau dua 30 mL / min: Tsis pom zoo hloov kho
CrCl 10 mL / min kom tsawg dua lossis sib npaug li 30 mL / min: Kev pom zoo thawj koob tshuaj yog ib nrab ntawm cov tshuaj pom zoo ib txwm (piv txwv li, ntshav siab, 5 mg; systolic plawv tsis ua haujlwm, 2.5 mg, thiab mob MI, 2.5 mg. Up titrate raws li kev zam rau qhov siab tshaj plaws ntawm 40 mg ib hnub twg)
CrCl tsawg dua 10 mL / min lossis ntawm hemodialysis: Kev pom zoo thawj koob tshuaj yog 2.5 mg ntawm qhov ncauj ib hnub ib zaug

Kev Kho Mob Siab

Cov neeg mob uas muaj tus kab mob jaundice los yog cim qhov siab ntawm cov enzymes hepatic yuav tsum tsis txhob siv txoj kev kho mob thiab tau txais kev kho mob tsim nyog.

Kev Kho Tshuaj

-Cov nyhuv antihypertensive tuaj yeem txo qis mus rau qhov kawg ntawm lub sijhawm noj tshuaj tsis hais txog ntawm cov tshuaj noj, tab sis feem ntau nrog cov koob tshuaj 10 mg lossis tsawg dua txhua hnub. Qhov no tuaj yeem ntsuas tau los ntawm kev ntsuas ntshav siab ua ntej noj tshuaj kom txiav txim siab seb puas muaj kev tswj hwm zoo rau 24 teev. Yog tias nws tsis yog, qhov nce ntawm koob tshuaj yuav tsum tau txiav txim siab. Yog tias ntshav siab tsis tswj tau zoo nrog lisinopril ib leeg, ib qho diuretic tuaj yeem ntxiv. Tom qab ntxiv cov tshuaj diuretic, nws tuaj yeem txo qhov koob tshuaj lisinopril.
-Nyob rau hauv tag nrho cov neeg mob uas muaj kev pheej hmoo siab, xws li cov neeg mob uas muaj ischemic plawv los yog kab mob cerebrovascular, nyob rau hauv uas ntau heev poob nyob rau hauv cov ntshav siab tej zaum yuav ua rau myocardial infarction los yog cerebrovascular kev huam yuaj, cov chaw tsim tshuaj paus qhia pib kev kho mob nyob rau hauv qis koob tshuaj.
- Kev kho tshuaj noj hauv cov neeg laus yuav tsum tau ua nrog ceev faj tshwj xeeb.
- Hauv cov neeg mob uas tam sim no tau kho nrog diuretic, cov tsos mob hypotension qee zaus tuaj yeem tshwm sim tom qab thawj koob tshuaj. Txhawm rau txo qis qhov tshwm sim ntawm hypotension, diuretic yuav tsum, yog tias ua tau, txiav tawm 2 mus rau 3 hnub ua ntej pib kho. Tom qab ntawd, yog tias ntshav siab tsis tswj nrog lisinopril ib leeg, kev kho diuretic yuav tsum rov pib dua. Yog tias kev kho diuretic tsis tuaj yeem txiav tawm, thawj koob tshuaj 5 mg yuav tsum tau siv nrog kev saib xyuas kev noj qab haus huv rau ob peb teev thiab kom txog thaum ntshav siab.

yuav ua li cas thiaj li ua tau zoo zaws

Cov kev ceev faj

US BOXED CEEB TOOM :
-FETAL TOXICITY: Angiotensin converting enzyme (ACE) inhibitor siv thaum cev xeeb tub tuaj yeem ua rau mob hnyav thiab tuag rau tus menyuam hauv plab. Thaum siv thaum lub sij hawm thib ob thiab thib peb trimesters, ACE inhibitors tau cuam tshuam nrog kev raug mob ntawm tus menyuam hauv plab thiab menyuam yaus, suav nrog kev mob ntshav siab, lub cev pob txha pob txha hypoplasia, anuria, rov qab los yog lub raum tsis ua haujlwm, thiab kev tuag. Oligohydramnios kuj tau tshaj tawm, suav tias yog tshwm sim los ntawm kev txo qis hauv lub raum ua haujlwm; oligohydramnios nyob rau hauv qhov chaw no tau txuam nrog fetal limb contractures, craniofacial deformation, thiab hypoplastic ntsws txoj kev loj hlob. Kev cuam tshuam rau ACE inhibitors thaum thawj peb lub hlis twg ntawm cev xeeb tub tau cuam tshuam nrog kev ua tsis tiav, kev loj hlob hauv plab, patent ductus arteriosus, lwm yam kev mob plawv tsis zoo, thiab kev puas hlwb neurological malformations. Thaum kuaj pom cev xeeb tub, ACE inhibitors yuav tsum tau txiav kom sai li sai tau. Yog tias tsis muaj lwm txoj hauv kev kho ACE inhibitor, cov neeg mob yuav tsum paub txog qhov txaus ntshai rau lawv cov fetuses thiab ib puag ncig intra-amniotic yuav tsum tau soj ntsuam los ntawm kev kuaj xyuas ultrasound. Yog tias oligohydramnios txhim kho, cov tshuaj no yuav tsum tau txiav tawm tshwj tsis yog tias nws tau txiav txim siab cawm txoj sia rau leej niam. Nyob ntawm lub lim tiam ntawm cev xeeb tub, kev kuaj kev ntxhov siab, kev sim tsis muaj kev ntxhov siab, lossis kev kuaj mob biophysical tej zaum yuav tsim nyog. Oligohydramnios yuav tsis tshwm sim txog thaum tom qab tus me nyuam hauv plab tau raug mob irreversible.

Kev nyab xeeb thiab kev ua tau zoo tsis tau tsim nyob rau hauv cov neeg mob hnub nyoog qis dua 6 xyoo.

Nrog rau WARNINGS seem rau kev ceev faj ntxiv.

Dialysis

Cov tshuaj no tuaj yeem raug tshem tawm los ntawm hemodialysis.

Lwm Cov Lus Qhia

Tswv yim tswv yim :
-Yuav tsum tau muab ib zaug ib hnub.
-Tej zaum muab nrog lossis tsis muaj zaub mov.
-Nyob rau hauv qee cov neeg mob uas muaj lub plawv tsis ua hauj lwm uas muaj cov ntshav siab li qub lossis tsis tshua muaj ntshav siab, kev txo qis ntawm cov ntshav siab ntxiv yuav tshwm sim nrog cov tshuaj no. Cov txiaj ntsig no tau xav txog thiab feem ntau tsis yog vim li cas thiaj li txiav kev kho mob. Yog tias hypotension dhau los ua cov tsos mob, kev txo koob tshuaj lossis txiav tawm yuav yog qhov tsim nyog.

General :
-Cov tshuaj no yog qhia raws li kev kho mob nrog diuretics thiab digitalis rau kev kho mob plawv tsis ua hauj lwm.
- Ua raws li thawj zaug MI, tag nrho cov ACE inhibitors, ntawm qhov sib piv cov koob tshuaj uas tsim nyog, zoo li ua tau zoo sib npaug rau kev txo qis kev tuag thiab rov muaj dua MI.
- Ua ntej kev kho mob, cov neeg mob uas muaj kev pheej hmoo siab ntawm cov tsos mob hypotension xws li cov neeg mob uas muaj ntsev depletion nrog lossis tsis muaj hyponatremia, hypovolemia lossis cov neeg tau txais kev kho mob diuretic yuav tsum tau kho cov mob no. Lub raum kev ua haujlwm thiab cov ntshav cov poov tshuaj yuav tsum tau saib xyuas.
-Yog tias nws tsis muaj peev xwm txiav tawm cov tshuaj diuretic ua ntej pib lisinopril, tus neeg mob yuav tsum tau saib xyuas zoo li ob peb teev tom qab thawj koob tshuaj no, thiab kom txog thaum cov ntshav siab nyob ruaj khov. Cov teebmeem antihypertensive ntawm lisinopril thiab diuretics siv ua ke yog kwv yees li ntxiv.
-Kev ua tau zoo ntawm kev txo cov ntshav siab yuav tsum tau 2 mus rau 4 lub lis piam kho.
-Acute myocardial infarction: Ntxiv rau cov tshuaj no, cov neeg mob yuav tsum tau txais, yog tias tsim nyog, cov kev kho mob xws li thrombolytics, aspirin, thiab beta-blocker.
-Antihypertensive teebmeem ntawm cov tshuaj no yog khaws cia thaum lub sij hawm ntev kho. Kev tshem tawm sai sai tsis tau cuam tshuam nrog kev nce ntshav siab sai, lossis nce ntshav siab ntau dua piv rau qib pretreatment.

Tus neeg mob cov lus qhia :
-Cov tshuaj no tuaj yeem noj nrog lossis tsis muaj zaub mov, tab sis yuav tsum tau noj tib lub sijhawm txhua hnub.
-Cov tshuaj no tuaj yeem ua rau koj lub peev xwm tsav tsheb lossis ua haujlwm tshuab.

Cov ntaub ntawv ntxiv

Nco ntsoov sab laj nrog koj tus kws kho mob kom paub meej tias cov ntaub ntawv uas tshwm sim hauv nplooj ntawv no siv tau rau koj tus kheej.