Lithium: 7 yam uas koj yuav tsum paub

1. Nws ua haujlwm li cas

  • Lithium tuaj yeem siv los kho mania cuam tshuam nrog kev puas siab puas ntsws bipolar. Cov kws tshaj lij tsis paub meej tias lithium ua haujlwm li cas tab sis ntseeg tias nws hloov pauv sodium thauj hauv paj hlwb thiab cov leeg hlwb uas kho cov metabolism hauv cov neurotransmitters hauv lub cell. Lithium yog ib yam khoom muaj nyob hauv ib puag ncig thiab peb lub cev.
  • Lithium belongs rau chav kawm ntawm cov tshuaj hu ua antimanic agents.

2. Upsides

  • Tej zaum yuav siv los kho tus mob manic los yog sib xyaw ua ke hauv cov neeg uas muaj kev puas siab puas ntsws bipolar 1 lossis kev puas siab puas ntsws bipolar 2.
  • Pom tau tias yog thawj tus neeg sawv cev rau kev kho thawj zaug ntawm kev nyuaj siab, kev xav, lossis kev sib xyaw ua ke hauv kev puas siab puas ntsws bipolar.
  • Tej zaum yuav raug siv ua ke nrog cov tshuaj atypical antipsychotic, lwm tus neeg saib xyuas kev ntxhov siab, lossis ib qho tshuaj tiv thaiv kev ntxhov siab los kho kev caij tsheb kauj vab lossis kev nyuaj siab ntau dua los yog sib xyaw ua ke.
  • Kev kho mus sij hawm ntev nrog lithium tiv thaiv lossis txo qis qhov kev siv ntawm cov ntu tom ntej ntawm mania.
  • Tau siv off-label rau kev kho mob ntawm kev nyuaj siab nyob rau hauv cov neeg uas tsis teb rau antidepressants.
  • Muaj kev txwv tsis pub siv rau kev kho tus mob schizophrenia lossis schizophrenia thiab tsuas yog yuav tsum tau txiav txim siab yog tias cov tshuaj tiv thaiv kev puas siab puas ntsws ua tsis tiav. tuaj yeem muab ntxiv rau kev kho mob uas twb muaj lawm; Txawm li cas los xij, ua tib zoo saib xyuas cov ntshav lithium concentrations, cov kev mob tshwm sim, lossis kev sib cuam tshuam ntawm cov tshuaj yog pom zoo.
  • Lwm yam kev siv cov ntawv sau npe suav nrog kev tsis txaus ntseeg ntawm kev tswj tsis tau, kev puas siab puas ntsws hauv cov menyuam yaus, neutropenia lossis ntshav ntshav, hyperthyroidism, lossis SIADH; Txawm li cas los xij, nws txoj kev siv yuav tsum tsuas yog xav txog yog tias lwm tus neeg ua haujlwm tsis zoo.
  • Kev ua tsis raug cai thiab tsis raug tsim txom.
  • Generic lithium yog muaj.

3. Kev poob qis

Yog tias koj muaj hnub nyoog ntawm 18 thiab 60 xyoo, tsis noj lwm yam tshuaj lossis tsis muaj lwm yam mob, cov kev mob tshwm sim uas koj yuav muaj xws li:

  • Cov tes tshee zoo, tso zis ntau zaus, thiab nqhis dej me ntsis feem ntau tshwm sim thaum pib lithium. Qee zaum cov teebmeem no tuaj yeem tshwm sim thaum kho.
  • Kev xeev siab thaum pib yog tshwm sim tab sis feem ntau txo qis nrog kev tswj hwm txuas ntxiv.
  • raws plab, ntuav, tsaug zog, cov leeg tsis muaj zog, tsis qab los noj mov, thiab kev sib koom ua ke nyuaj yuav yog ib qho kev qhia ntxov ntawm lithium toxicity. kiv taub hau, qhov muag tsis pom kev, ringing hauv pob ntseg thiab ntau dhau ntawm cov zis dilute yuav tshwm sim nrog ntau dua (tshuaj lom) lithium. Nrhiav kev kho mob sai sai.
  • Lithium kuj tseem tuaj yeem ua rau lub plawv dhia tsis zoo, ziab thiab thinning ntawm cov plaub hau, alopecia, qhov ncauj qhuav, hnyav nce, khaus, thiab lwm yam kev mob tshwm sim. Kev siv sijhawm ntev tuaj yeem ua rau mob raum, ntshav siab calcium ntau, hyperparathyroidism, hypothyroidism, lossis lwm yam teeb meem thyroid.
  • Tej zaum yuav xav tau ntau koob tshuaj txhua hnub. Cov ntsiav tshuaj, tshuaj ntsiav, lossis tshuaj hauv qhov ncauj yuav tsum tau noj 3 lossis 4 zaug hauv ib hnub - kev noj tshuaj tsawg dua tuaj yeem cuam tshuam nrog kev mob plab lossis lub paj hlwb. Kev npaj ncua kev tso tawm tuaj yeem muab 2 mus rau 3 zaug ib hnub.
  • Kev noj tshuaj yuav nyuaj vim tias tsis muaj ntau ntawm cov npoo ntawm cov tshuaj lithium txaus thiab cov tshuaj lom. Cov chaw yuav tsum muaj uas tuaj yeem saib xyuas cov ntshav lithium kom sai thiab raug.
  • Yog tias muaj toxicity tshwm sim, txiav tawm ib ntus rau 24 mus rau 48 teev tom qab ntawd rov pib dua ntawm qhov qis dua.
  • Kev saib xyuas yuav tsum tau ua thiab yuav tsum tau ua ob zaug ib lub lim tiam thaum pib kho thiab tom qab ntawd txhua ob lub hlis mus sij hawm ntev.
  • Tsis haum rau cov neeg uas muaj lub raum loj lossis kab mob plawv, uas tsis muaj zog, lub cev qhuav dej, noj cov tshuaj diuretics, nrog rau qib sodium tsawg, lossis noj zaub mov txwv sodium. Hauv cov xwm txheej tshwj xeeb, lithium tuaj yeem siv tau yog tias tus neeg mob tus mob ua rau muaj kev phom sij rau lub neej thiab lwm yam kev kho mob ua tsis tiav.
  • Tsis pom zoo rau cov menyuam yaus hnub nyoog qis dua 12 xyoos. Kev siv lithium tuaj yeem ua rau muaj kev tsis sib haum xeeb ntawm Brugada syndrome (ib qho kev mob plawv uas tshwm sim los ntawm qhov txawv txav ntawm ECG thiab kev pheej hmoo ntawm kev tuag tam sim ntawd).
  • Qhov ntau ntawm cov teebmeem ntawm lithium hauv cev xeeb tub tsis tau txiav txim siab tag nrho yog li cov kws tshaj lij pom zoo kom cov poj niam zam lithium, tshwj xeeb tshaj yog nyob rau thawj peb lub hlis twg. Lithium tau cuam tshuam nrog fetal toxicity, xws li mob plawv, tshwj xeeb tshaj yog Ebstein's anomaly. Yog tias muab thaum cev xeeb tub, cov tshuaj lithium feem ntau yuav tsum tau nce ntxiv tab sis yuav tsum tau txo qis 1 lub lis piam ua ntej yug menyuam lossis thaum pib ua haujlwm.
  • Tej zaum yuav cuam tshuam nrog ntau yam tshuaj xws li diuretics (cov tshuaj dej), NSAIDs, thiab ACE inhibitors.
  • Kev sib cuam tshuam lossis kev noj ntau dhau tuaj yeem ua rau serotonin syndrome (cov tsos mob suav nrog kev hloov pauv ntawm lub hlwb [xws li kev ntxhov siab, hnov ​​​​lus, tsis nco qab, delirium]), lub plawv dhia ceev, kiv taub hau, dej ntws tawm, leeg tshee lossis rigidity, thiab mob plab (xws li xeev siab, ntuav, thiab raws plab. ).

Nco tseg: Feem ntau, cov neeg laus lossis cov menyuam yaus, cov neeg uas muaj qee yam mob (xws li mob siab lossis mob raum, kab mob plawv, ntshav qab zib, qaug dab peg) lossis cov neeg noj lwm cov tshuaj muaj kev pheej hmoo ntau dua ntawm cov kev mob tshwm sim. Saib daim ntawv teev tag nrho cov kev mob tshwm sim



4. Kab hauv qab

Lithium tuaj yeem siv los kho cov mob manic uas cuam tshuam nrog kev puas siab puas ntsws bipolar; Txawm li cas los xij, muaj txoj kab zoo ntawm ntau dhau thiab tsawg dhau, thiab kev soj ntsuam txuas ntxiv yog xav tau los tiv thaiv lithium toxicity.

ua 3675mg

5. Cov lus qhia

  • Lithium feem ntau yog noj ob mus rau peb zaug ib hnub nrog zaub mov (ntxiv-tso npaj) lossis 3 mus rau 4 zaug ib hnub nrog zaub mov (cov ntsiav tshuaj / tshuaj ntsiav / tshuaj). Kev tswj hwm nrog zaub mov thiab ntau zaus thoob plaws ib hnub tau cuam tshuam nrog kev cuam tshuam ntawm plab hnyuv.
  • Muaj ib txoj kab zoo ntawm ntau dhau thiab tsawg dhau lithium. Ib txwm coj lithium raws nraim li qhia thiab mus rau koj lub sijhawm teem tseg. Tsis txhob noj tshuaj ntsuab lossis tshuaj kho tom khw muag khoom yam tsis tau sab laj nrog koj tus kws kho mob lossis tus kws muag tshuaj ua ntej vim tias ntau cov tshuaj yuav cuam tshuam rau cov ntshav lithium.
  • Yog tias koj tsis nco ib koob tshuaj lithium, noj sai li sai tau thaum koj nco qab. Yog tias nws nyob ze rau koj qhov koob tshuaj ntxiv, tsis txhob muab ob npaug rau ntawm qhov koob tshuaj.
  • Tsis txhob zuaj lossis zom cov ntsiav tshuaj txuas ntxiv; nqos tag nrho.
  • Muaj caffeine ntau dhau tuaj yeem txo cov lithium hauv koj lub cev. Yog tias koj txiav tawm ntsev los ntawm koj cov zaub mov, qhov no tuaj yeem cuam tshuam cov ntshav lithium.
  • Lithium tuaj yeem cuam tshuam koj lub siab lub ntsws lossis ua rau koj tsaug zog. Tsis txhob tsav tsheb kom txog thaum koj paub tias lithium yuav cuam tshuam koj li cas. Tsis txhob haus cawv.
  • Xyuas kom koj khaws dej kom txaus thaum noj lithium thiab tswj kom muaj ntsev txaus (koj tus kws kho mob yuav tham txog qhov yuav tsum tau ua). Qhov kev pheej hmoo ntawm kev phiv ntawm lithium yog nce yog tias koj lub cev qhuav dej, lossis yog tias koj muaj dej ntau dhau. Kev tawm hws ntau dhau los yog raws plab kuj tuaj yeem ua rau qhov tsis txaus ntawm lithium hauv cov ntshav.
  • Hu rau koj tus kws kho mob yog tias koj mob lossis muaj kab mob vim tias koj cov tshuaj lithium yuav tsum tau hloov pauv lossis txiav tawm ib ntus.
  • Nrhiav kev kho mob sai yog tias cov tsos mob zoo ib yam li ntshav qab zib (xws li nqhis dej ntau dhau lossis tso zis ntau dhau) tshwm sim.
  • Nres lithium thiab tiv tauj koj tus kws kho mob sai yog tias cov tsos mob ntawm lithium toxicity xws li raws plab, ntuav, tshee, tsaug zog, leeg tsis muaj zog, lossis tsis meej pem tshwm sim.
  • Nrhiav kev kho mob sai sai yog tias cov tsos mob zoo ib yam nrog serotonin syndrome (xws li kev ntxhov siab, hnov ​​​​lus, lub plawv dhia ceev, kiv taub hau, yaug, xeev siab, raws plab) tshwm sim.
  • Koj yuav tsum tau mus kuaj ntshav tsis tu ncua thaum koj noj lithium kom paub meej tias cov koob tshuaj tsim nyog rau koj.
  • Tej zaum yuav cuam tshuam rau koj lub hlwb thiab lub cev muaj peev xwm yog li ua tib zoo tsav tsheb lossis ua haujlwm tshuab kom txog thaum koj paub tias lithium cuam tshuam rau koj li cas.
  • Tsis txhob noj lwm yam tshuaj, suav nrog cov yuav hauv lub txee, yam tsis tau kuaj xyuas nrog koj tus kws kho mob lossis tus kws muag tshuaj ua ntej tias lawv sib haum nrog lithium.
  • Tham nrog koj tus kws kho mob yog tias koj tab tom xav txog kev xeeb tub los yog twb cev xeeb tub ua ntej koj tau txais cov tshuaj lithium. Txawm hais tias lithium tuaj yeem ua rau muaj kev phom sij rau menyuam hauv plab, qee zaum cov txiaj ntsig zoo dua qhov txaus ntshai. Qhia rau koj tus kws kho mob tam sim yog tias koj cev xeeb tub tsis tshwm sim.

6. Teb thiab ua tau zoo

  • Lithium yog absorbed tag nrho nyob rau hauv lub plab hnyuv ib ntsuj av tau nrog lub ncov theem tshwm sim 0.25 mus rau 3 teev tom qab lub qhov ncauj tswj ntawm tam sim-tso npaj thiab ob mus rau rau teev tom qab sustained-tso npaj.
  • Kev txo qis ntawm cov tsos mob manic yuav tsum pom nyob rau hauv 5 mus rau 7 hnub tab sis tag nrho cov kev kho mob yuav tsum tau 10 mus rau 21 hnub.
  • Lithium concentrations yuav tsum tau txiav txim tam sim ntawd ua ntej koob tshuaj ntxiv (piv txwv li, 8 mus rau 12 teev tom qab lithium koob tshuaj dhau los). Tag nrho kev cia siab yuav tsum tsis txhob muab tso rau hauv cov ntshav lithium ib leeg thiab suav nrog kev soj ntsuam kev soj ntsuam ntawm tus neeg mob cov lus teb.
  • Cov ntshav lithium concentrations ntawm 1-1.2 mEq / L feem ntau yuav tsum tau thaum lub sij hawm mob manic mob (concentrations yuav tsum tsis txhob ntau tshaj 1.5 mEq / L thaum lub sij hawm kho mob).
  • 5mL ntawm lithium citrate tov muaj txog 8mEq ntawm lithium thiab yog kwv yees li 300mg ntawm lithium carbonate.

7. Kev sib tham

Cov tshuaj uas cuam tshuam nrog lithium tuaj yeem txo qis nws cov txiaj ntsig, cuam tshuam ntev npaum li cas nws ua haujlwm rau, ua rau muaj kev phiv ntau ntxiv, lossis muaj qhov cuam tshuam tsawg dua thaum noj nrog lithium. Kev sib cuam tshuam ntawm ob cov tshuaj tsis yog ib txwm txhais tau tias koj yuav tsum tsis txhob noj ib yam tshuaj; txawm li cas los xij, qee zaum nws ua. Tham nrog koj tus kws kho mob txog yuav ua li cas kev sib cuam tshuam tshuaj yuav tsum tau tswj.

Cov tshuaj nquag uas tuaj yeem cuam tshuam nrog lithium suav nrog:

  • acetazolamide
  • aminophylline
  • antacids uas muaj sodium bicarbonate
  • anticonvulsants, xws li carbamazepine, fosphenytoin, phenytoin, phenobarbital, los yog primidone
  • antidepressants, xws li tricyclic antidepressants (xws li, amitriptyline), monoamine oxidase inhibitors (xws li, isocarboxazid, phenelzine, thiab tranylcypromine), los yog SSRIs (xws li, fluoxetine, sertraline)
  • antipsychotics (xws li butyrophenones, phenothiazine, los yog thioxanthenes) thiab atypical antipsychotics (xws li olanzapine, quetiapine, ziprasidone)
  • txhua yam tshuaj uas yuav ncua lub sijhawm QTc, xws li amiodarone lossis haloperidol
  • calcium channel blockers, xws li diltiazem lossis verapamil
  • diuretics, xws li furosemide lossis HCTZ
  • Cov tshuaj hauv plawv, xws li digoxin, ACE inhibitors (xws li captopril, enalapril, lossis lisinopril), angiotensin II receptor antagonists (xws li candesartan lossis irbesartan), lossis beta-blockers (xws li atenolol lossis sotalol)
  • iodides
  • tshuaj metronidazole
  • Cov tshuaj migraine, xws li almotriptan, eletriptan, lossis sumatriptan
  • NSAIDs, xws li ibuprofen, diclofenac, lossis naproxen
  • opioids (xws li codeine, morphine)
  • sodium chloride
  • tshuaj tetracycline
  • Lwm cov tshuaj uas cuam tshuam rau serotonin, xws li amphetamines, dextromethorphan, fentanyl, ondansetron, tramadol, los yog St. John's Wort.

Tej zaum yuav ncua cov teebmeem ntawm cov tshuaj tiv thaiv neuromuscular (xws li pancuronium lossis succinylcholine).

Tsis txhob haus cawv lossis noj tshuaj txhaum cai lossis ua si thaum noj lithium.

Nco ntsoov tias daim ntawv teev npe no tsis suav nrog thiab suav nrog tsuas yog cov tshuaj uas tuaj yeem cuam tshuam nrog lithium. Koj yuav tsum xa mus rau cov ntaub ntawv sau npe rau lithium rau tag nrho cov npe ntawm kev sib cuam tshuam.

Cov ntaub ntawv

Lithium. Kho tshiab 08/2019. find-drugs-conditionsppa/lithium.html

Cov ntaub ntawv ntxiv

Nco ntsoov, khaws cov tshuaj no thiab lwm yam tshuaj kom deb ntawm menyuam yaus, tsis txhob muab koj cov tshuaj rau lwm tus, thiab siv lithium nkaus xwb rau cov lus qhia.

Nco ntsoov sab laj nrog koj tus kws kho mob kom paub meej tias cov ntaub ntawv uas tshwm sim hauv nplooj ntawv no siv tau rau koj tus kheej.

Copyright 1996-2021 Drugs.com. Hloov kho hnub: Lub Peb Hlis 25, 2021.