Siv rau cov hauv qab no muaj zog: 10 mg / mL; 10 mg / 12.5 mL; 20 mg; 25 mg; 50 mg; 100 mg
Ib txwm Adult Dose rau:
Ib txwm Geriatric Dose rau:
Cov lus qhia txog kev noj tshuaj ntxiv:
Ib txwm siv rau cov neeg laus noj rau erectile kawg
Thawj koob tshuaj: 50 mg ntawm qhov ncauj ib hnub ib zaug, raws li xav tau, 1 teev ua ntej kev sib deev
Kev Kho Mob: 25 mus rau 100 mg ntawm qhov ncauj ib hnub ib zaug, raws li xav tau, 1 teev ua ntej kev sib deev
Lus Cim: Cov tshuaj no tuaj yeem noj nyob qhov twg los ntawm 30 feeb mus rau 4 teev ua ntej kev sib deev.
Siv: Kho ntawm erectile kawg
Ib txwm siv rau cov neeg laus noj rau Pulmonary Hypertension
Kev hloov pauv (R) :
Qhov ncauj :
-Cov koob tshuaj pib: 5 lossis 20 mg ntawm qhov ncauj peb zaug hauv ib hnub, 4 mus rau 6 teev sib nrug.
-Cov koob tshuaj ntau tshaj: 20 mg ntawm qhov ncauj peb zaug hauv ib hnub
Txhaj tshuaj :
-Cov koob tshuaj pib: 2.5 lossis 10 mg IV bolus peb zaug ib hnub
Cov lus pom :
-Tsis muaj qhov ua tau zoo dua nrog cov koob tshuaj qhov ncauj ntau dua li qhov siab tshaj plaws tau pom zoo.
-Ib koob tshuaj 10 mg yog kwv yees kom muab cov tshuaj pharmacological sib npaug rau 20 mg ntawm qhov ncauj.
Siv: Kev kho PAH (WHO Pawg I) hauv cov neeg laus kom txhim kho kev tawm dag zog thiab ncua kev kho mob tsis zoo
Ib txwm Geriatric Dose rau Erectile Dysfunction
Thawj koob tshuaj: 25 mg ntawm qhov ncauj ib hnub ib zaug 1 teev ua ntej kev sib deev
Siv: Kho ntawm erectile kawg
Renal Dose Adjustments
Erectile kawg :
- Mob me me rau lub raum tsis ua haujlwm (CrCl 30 txog 80 mL / min): Tsis pom zoo kho.
- mob raum ua haujlwm tsis zoo (CrCl tsawg dua 30 mL / min): 25 mg ntawm qhov ncauj ib hnub ib zaug 1 teev ua ntej kev sib deev
Pulmonary Arterial Hypertension :
Kev hloov pauv (R) :
-Tsis pom zoo kho.
Kev Kho Mob Siab
Erectile kawg :
-Cov koob tshuaj thawj zaug: 25 mg ntawm qhov ncauj yuav tsum tau txiav txim siab rau cov neeg mob uas muaj kev puas siab puas ntsws siab.
Pulmonary Arterial Hypertension :
Kev hloov pauv (R) :
- Mob me me mus rau nruab nrab tsis ua haujlwm siab (Child-Pugh Class A thiab B): Tsis pom zoo hloov kho.
-Kev mob siab hnyav (Child-Pugh Class C): Tsis tau kawm
Kev Kho Tshuaj
Concomitant tswj nrog alpha blockers :
-Cov koob tshuaj pib: 25 mg ntawm qhov ncauj 1 teev ua ntej kev sib deev
-Cov neeg mob yuav tsum ruaj khov ntawm kev kho alpha blocker ua ntej pib kho nrog cov tshuaj no.
Concomitant kev tswj hwm nrog ritonavir :
-Cov koob tshuaj pib: 25 mg ntawm qhov ncauj 1 teev ua ntej kev sib deev
-Cov koob tshuaj ntau tshaj: 25 mg hauv 48 teev
Kev tswj hwm nrog CYP450 3A4 inhibitors (ketoconazole, itraconazole, saquinavir) lossis erythromycin :
-Cov koob tshuaj pib: 25 mg ntawm qhov ncauj 1 teev ua ntej kev sib deev
Revatio (R) rau kev kho mob pulmonary arterial hypertension nyob rau hauv cov neeg laus: ceev faj yog pom zoo thaum xaiv los yog kho koob tshuaj nyob rau hauv cov pej xeem no.
Cov kev ceev faj
Kev nyab xeeb thiab kev ua tau zoo tsis tau tsim nyob rau hauv cov neeg mob hnub nyoog qis dua 18 xyoo.
Nrog rau WARNINGS seem rau kev ceev faj ntxiv.
Dialysis
Cov ntaub ntawv tsis muaj
Lwm Cov Lus Qhia
Tswv yim tswv yim :
-Cov tshuaj no tuaj yeem noj nrog lossis tsis muaj zaub mov.
-Revatio (R) IV txhaj yog rau kev kho mob txuas ntxiv ntawm cov neeg mob pulmonary arterial hypertension (PAH) tam sim no noj qhov ncauj Revatio (R) thiab tsis tuaj yeem noj tshuaj qhov ncauj ib ntus.
General :
-Cov tshuaj no yog qhia rau kev kho mob ntawm erectile kawg nyob rau hauv cov txiv neej cov neeg laus cov neeg mob, thiab kuj yog marketed li Revatio (R) los kho PAH rau cov me nyuam thiab cov neeg laus.
-Kev txwv kev siv: Ntxiv Revatio (R) rau bosentan txoj kev kho tsis ua rau muaj txiaj ntsig zoo ntawm kev tawm dag zog lub cev.
Saib xyuas :
- Mob plawv: ntshav siab
Tus neeg mob cov lus qhia :
-Cov tshuaj no tsis muaj kev tiv thaiv kab mob sib deev. Xav txog kev tiv thaiv tiv thaiv kab mob sib kis.
-Cov neeg mob yuav tsum nrhiav kev kho mob tam sim ntawd thaum muaj qhov tsis pom kev tam sim ntawd hauv ib lossis ob lub qhov muag thaum noj cov tshuaj no.
-Cov neeg mob yuav tsum nrhiav kev kho mob tam sim ntawd thaum muaj qhov tshwm sim sai sai lossis tsis hnov lus thaum noj cov tshuaj no.
-Cov neeg mob noj Revatio (R) yuav tsum tsis txhob noj sildenafil rau erectile kawg lossis lwm yam PDE-5 inhibitors.
Cov ntaub ntawv ntxiv
Nco ntsoov sab laj nrog koj tus kws kho mob kom paub meej tias cov ntaub ntawv uas tshwm sim hauv nplooj ntawv no siv tau rau koj tus kheej.
