Suboxone Side Effects

Lub npe dav: buprenorphine / naloxone

Nco tseg: Cov ntaub ntawv no muaj cov ntaub ntawv cuam tshuam txog buprenorphine / naloxone. Qee cov ntaub ntawv noj tshuaj uas tau teev tseg rau ntawm nplooj ntawv no yuav tsis thov rau lub npe khoom npe Suboxone.



Hauv Summary

Cov kev phiv tshwm sim ntawm Suboxone muaj xws li: cem quav, raws plab, mob taub hau, thiab xeev siab. Saib hauv qab no kom paub cov npe ntawm cov teebmeem tsis zoo.

Rau Cov Neeg Siv Khoom

Siv rau buprenorphine / naloxone : film, ntsiav tshuaj

Kev mob tshwm sim yuav tsum tau mus kho mob tam sim

Nrog rau nws cov teebmeem xav tau, buprenorphine / naloxone tuaj yeem ua rau qee qhov tsis xav tau. Txawm hais tias tsis yog tag nrho cov kev mob tshwm sim no tuaj yeem tshwm sim, yog tias lawv tshwm sim lawv yuav xav tau kev kho mob.

Nrog koj tus kws kho mob tham tam sim ntawd Yog tias ib qho ntawm cov kev mob tshwm sim hauv qab no tshwm sim thaum noj buprenorphine / naloxone:

Feem ntau

  • Ua daus no
  • hnoos
  • xav tias faint, kiv taub hau, los yog lightheaded
  • kev xav ntawm warmth los yog kub
  • ua npaws
  • dej los yog liab ntawm daim tawv nqaij, tshwj xeeb tshaj yog nyob rau ntawm lub ntsej muag thiab caj dab
  • mob taub hau
  • hnov lus
  • sab nraub qaum lossis sab mob
  • mob los yog tso zis nyuaj
  • tawm hws

Qhov xwm txheej tsis paub

  • Kev ntxhov siab
  • mob plab los yog o ntawm lub ntsej muag, caj npab, tes, ceg qis, lossis ko taw
  • darkening ntawm daim tawv nqaij
  • raws plab
  • nyuaj nqos
  • kiv taub hau
  • ua tsis taus pa
  • lub plawv dhia ceev
  • khaus khaus , khaus, daim tawv nqaij ua pob
  • poob qab los noj mov
  • puas hlwb kev nyuaj siab
  • xeev siab
  • overactive reflexes
  • kev sib koom tes tsis zoo
  • puffiness los yog o ntawm daim tawv muag los yog ib ncig ntawm lub qhov muag, ntsej muag, daim di ncauj, los yog tus nplaig
  • hnyav nce sai
  • kev ntxhov siab tshee tshee hais lus lossis ua yeeb yam nrog kev zoo siab koj tsis tuaj yeem tswj nruj hauv siab
  • tingling ntawm tes los yog ko taw
  • tshee los yog tshee tshee
  • hnyav nce lossis poob
  • ntuav

Tau txais kev pab thaum muaj xwm txheej ceev yog tias muaj cov tsos mob hauv qab no ntawm kev noj tshuaj ntau dhau thaum noj buprenorphine / naloxone:

Cov tsos mob ntawm overdose

  • Qhov muag tsis pom kev
  • tsis meej pem
  • ua tsis taus pa nyuaj lossis teeb meem
  • kiv taub hau, faintness, los yog lightheadedness thaum sawv tam sim ntawd los ntawm ib qho chaw pw los yog zaum
  • qaug zog
  • irregular, ceev, qeeb, los yog ua pa ntiav
  • daj ntseg lossis xiav daim di ncauj, ntiv tes, lossis daim tawv nqaij
  • pinpoint cov menyuam kawm ntawv
  • so thiab so kom txaus
  • pw tsaug zog
  • nkees nkees lossis qaug zog

Kev mob tshwm sim tsis tas yuav tsum tau kho mob tam sim

Qee qhov kev mob tshwm sim ntawm buprenorphine / naloxone tuaj yeem tshwm sim uas feem ntau tsis xav tau kev kho mob . Cov kev mob tshwm sim no yuav ploj mus thaum kho raws li koj lub cev hloov kho rau cov tshuaj. Tsis tas li ntawd, koj tus kws kho mob yuav tuaj yeem qhia koj txog txoj hauv kev los tiv thaiv lossis txo qee qhov kev mob tshwm sim.

Tshawb xyuas nrog koj tus kws kho mob yog tias muaj cov kev mob tshwm sim hauv qab no txuas ntxiv los yog thab plaub los yog koj muaj lus nug txog lawv:

Feem ntau

  • Nyuaj mob plab hnyuv
  • tsis muaj lossis tsis muaj zog
  • mob plab
  • teeb meem pw tsaug zog

Tsawg dua

Qhov xwm txheej tsis paub

  • Kub los yog mob qhov ncauj
  • khaus, khaus, khaus, ua tsis taus pa , prickling, 'pins thiab koob', los yog tingling xav nyob rau hauv lub qhov ncauj
  • poob los yog poob ntawm libido los yog kev sib deev muaj siab
  • chim siab
  • kev xav swings
  • tsis zoo concentration
  • liab, o, los yog mob ntawm tus nplaig
  • txo cov leeg nqaij
  • o, o, lossis liab ntawm lub qhov ncauj

Rau Cov Kws Kho Mob

Siv rau buprenorphine / naloxone: buccal film, sublingual film, sublingual ntsiav tshuaj

General

Cov tsos mob tshwm sim feem ntau pom muaj xws li mob taub hau, xeev siab, ntuav, hyperhidrosis , cem quav , cov cim qhia thiab cov tsos mob ntawm kev tshem tawm, insomnia , mob thiab peripheral edema . Tsis tas li ntawd, qhov ncauj hypoesthesia tau tshaj tawm nrog zaj duab xis sublingual.[ Ref ]

Lwm yam

Feem ntau (10% lossis ntau dua): Mob (22.4%)

amoxicillin / clavulanic acid ceeb toom

Feem ntau (1% mus rau 10%): Asthenia, chills, pyrexia, malaise, raug mob, pob ntseg

Tsis tshua muaj (0.1% mus rau 1%): Hypothermia, kub stroke

Postmarketing qhia : Vertigo [ Ref ]

Lub paj hlwb

Feem ntau (10% lossis ntau dua): Mob taub hau (36.4%)

daim ntawv teev kev ntxhov siab thiab kev nyuaj siab

Feem ntau (1% mus rau 10%): Migraine , kiv taub hau, hypertonia, paraesthesia, somnolence

Tsis tshua muaj (0.1% mus rau 1%): Amnesia, convulsion, hyperkinesia, hais lus tsis meej, tshee

Buprenorphine:

Postmarketing qhia : Neonatal tshem tawm syndrome nrog rau cov tsos mob ntawm hypertonia, neonatal tremor, neonatal agitation, thiab myoclonus; ceeb toom ntawm cov me nyuam mos convulsions, apnea, ua pa nyuaj siab , thiab bradycardia [ Ref ]

Ua pa

Buprenorphine-naloxone:

Feem ntau (1% mus rau 10%): Pharyngitis rhinitis, hnoos, sinusitis, kab mob ua pa sab sauv, mob hawb pob bronchitis, ua tsis taus pa , mob ntsws o , nce hnoos qeev

Tsis tshua muaj (0.1% mus rau 1%): Yawning

Zaus tsis qhia : Rhinorrhea

Buprenorphine:

Zaus tsis qhia : Ua pa nyuaj siab, coma, tuag[ Ref ]

Muaj cov ntawv tshaj tawm tom khw muag khoom coma thiab kev tuag cuam tshuam nrog kev siv buprenorphine thiab tshuaj benzodiazepines ; ntau ntawm cov ntawv ceeb toom no tau cuam tshuam kev siv tsis raug los ntawm kev txhaj tshuaj rau tus kheej.[ Ref ]

plab hnyuv

Feem ntau (10% lossis ntau dua): cem quav (12.1%), xeev siab (15%), mob plab (11.2%)

Feem ntau (1% mus rau 10%): ntuav, raws plab, dyspepsia , flatulence , qhov ncauj hypoesthesia

Tsis tshua muaj (0.1% mus rau 1%): Qhov ncauj ulceration, nplaig discoloration, hniav abscess glossodynia, mucosal erythema (qhov ncauj), mob hniav

Zaus tsis qhia : Mob plab,

Postmarketing qhia : Stomatitis glossitis, nplaig mob, pancreatitis [ Ref ]

Endocrine

Feem ntau (1% mus rau 10%): Erectile kawg , txo libido

Tsis tshua muaj (0.1% mus rau 1%): Amenorrhea ejaculation teeb meem, menorrhagia , metrorrhagia

Postmarketing qhia : Kev xeeb tub

Opioids :

Postmarketing qhia : Adrenal tsis txaus , androgen deficiency[ Ref ]

Mob siab heev

Buprenorphine:

Zaus tsis qhia : hypersensitivity tshwm sim nrog rau bronchospasm, angioneurotic edema , thiab anaphylactic poob siab ; feem ntau tshaj tawm raws li pob khaus khaus, thiab pruritus

tuaj yeem ua rau tylenol ua rau raws plab

Naloxone:

Zaus tsis qhia : hypersensitivity tshwm sim nrog rau bronchospasm, angioneurotic edema, thiab anaphylactic shock; Feem ntau tshaj tawm raws li pob khaus khaus, thiab pruritus[ Ref ]

Hauv zos

Postmarketing qhia Glossodynia, qhov ncauj mucosal erythema, qhov ncauj hypoesthesia, stomatitis[ Ref ]

Mob plawv

Feem ntau (1% mus rau 10%): vasodilation, kub siab

Tsis tshua muaj (0.1% mus rau 1%): Angina pectoris bradycardia, myocardial infarction, palpitations , tachycardia , hypotension , mob hauv siab

Postmarketing qhia : Peripheral edema, syncope , orthostatic hypotension , lub plawv dhia thiab atherosclerosis[ Ref ]

Ocular

Feem ntau (1% mus rau 10%): Amblyopia, lacrimal disorder

Tsis tshua muaj (0.1% mus rau 1%): Conjunctivitis , miv[ Ref ]

Mob siab

Hauv kev sim tshuaj thiab hauv cov ntawv tshaj tawm kev lag luam, cov neeg mob cytolytic kab mob siab thiab kab mob siab nrog daj daj tau tshaj tawm nyob rau hauv koom nrog kev siv buprenorphine. Lub spectrum ntawm kev txawv txav muaj xws li los ntawm kev hloov pauv asymptomatic siab ntawm hepatic transaminases mus rau hepatic tsis ua hauj lwm, hepatic necrosis, hepatorenal syndrome, thiab hepatic encephalopathy . Lub xub ntiag ntawm preexisting siab enzyme abnormalities, kab mob siab kab mob siab, concomitant hepatotoxic tshuaj siv, thiab tsis tu ncua IV. siv tshuaj yeeb tej zaum yuav tau ua lub luag haujlwm tseem ceeb los yog koom nrog.[ Ref ]

Buprenorphine-naloxone:

Feem ntau (1% mus rau 10%): txawv txav kuaj lub siab ua haujlwm

Buprenorphine:

Zaus tsis qhia : Cytolytic kab mob siab, kab mob siab nrog jaundice, ncua asymptomatic nce siab ntawm hepatic transaminases, hepatic tsis ua hauj lwm, hepatic necrosis, hepatorenal syndrome, thiab hepatic encephalopathy .[ Ref ]

Kev puas siab puas ntsws

Feem ntau (1% mus rau 10%): Kev ntxhov siab , kev nyuaj siab, ntxhov siab vim, kev xav txawv txav

Tsis tshua muaj (0.1% mus rau 1%): npau suav txawv txav, ntxhov siab, apathy, depersonalization, tshuaj dependence , euphoric mus ob peb vas, hostility

neo synephrine qhov ntswg tsuag

Zaus tsis qhia : Kev ntxhov siab, ntxhov siab

Postmarketing qhia : Hallucination, sim tua tus kheej, insomnia[ Ref ]

Dermatology

Feem ntau (10% lossis ntau dua): hws (14%)

Feem ntau (1% mus rau 10%): pruritus, ua pob, urticaria , ecchymosis

Tsis tshua muaj (0.1% mus rau 1%): Pob txuv , alopecia dermatitis exfoliative, tawv nqaij qhuav , daim tawv nqaij loj, herpes simplex, daim tawv nqaij nodule

Zaus tsis qhia : Piloerection, hws txias[ Ref ]

Cov kab mob genitourinary

Feem ntau (1% mus rau 10%): tso zis txawv txav

Tsis tshua muaj (0.1% mus rau 1%): kab mob urinary, kab mob ntawm qhov chaw mos, albuminuria, dysuria , hematuria , tso zis [ Ref ]

Hematology

Tsis tshua muaj (0.1% mus rau 1%): anemia, leucocytosis, leukopenia, lymphadenopathy , thrombocytopenia [ Ref ]

Immunologic

Feem ntau (1% mus rau 10%): Mob khaub thuas , kab mob[ Ref ]

Metabolic

Tsis tshua muaj (0.1% mus rau 1%): Txo qab los noj mov, hyperglycemia, hyperlipidemia , hypoglycemia , poob phaus[ Ref ]

Musculoskeletal

Feem ntau (1% mus rau 10%): Mob nraub qaum, mob caj dab, leeg nqaij, myalgia, caj dab txhav, ceg cramps, pob qij txha

Tsis tshua muaj (0.1% rau 1%): Mob caj dab

Zaus tsis qhia : Arthralgia[ Ref ]

Lub raum

Tsis tshua muaj (0.1% mus rau 1%): Nephrolithiasis , ntshav creatinine nce[ Ref ]

Cov ntaub ntawv

1. Cerner Multum, Inc. 'UK Summary of Product Characteristics.' O 0

2. 'Cov ntaub ntawv khoom. Bunavail (buprenorphine-naloxone). BioDelivery Sciences International, Inc., Raleigh, NC.

3. Cerner Multum, Inc. 'Australian Product Information.' O 0

4. 'Cov ntaub ntawv khoom. Subutex (buprenorphine). Reckitt thiab Colman Pharmaceuticals Inc, Richmond, VA.

5. 'Cov ntaub ntawv khoom. Zubsolv (buprenorphine-naloxone). Orexo US, Inc, New York City, NY.

Cov ntaub ntawv ntxiv

Nco ntsoov sab laj nrog koj tus kws kho mob kom paub meej tias cov ntaub ntawv uas tshwm sim hauv nplooj ntawv no siv tau rau koj tus kheej.

Qee qhov kev mob tshwm sim yuav tsis qhia. Koj tuaj yeem qhia lawv mus rau lub FDA .