Sulfamethoxazole / trimethoprim Cov teebmeem tshwm sim

Rau Cov Neeg Siv Khoom

Siv rau sulfamethoxazole / trimethoprim : qhov ncauj tshem tawm, qhov ncauj ntsiav tshuaj

Lwm hom tshuaj noj:



Kev mob tshwm sim yuav tsum tau mus kho mob tam sim

Nrog rau nws cov teebmeem xav tau, sulfamethoxazole / trimethoprim tuaj yeem ua rau qee qhov tsis xav tau. Txawm hais tias tsis yog tag nrho cov kev mob tshwm sim no tuaj yeem tshwm sim, yog tias lawv tshwm sim lawv yuav xav tau kev kho mob.

Nrog koj tus kws kho mob tham tam sim ntawd Yog tias ib qho ntawm cov kev mob tshwm sim hauv qab no tshwm sim thaum noj sulfamethoxazole / trimethoprim:

Feem ntau

  • Dub, tarry quav
  • blistering, tev, los yog loosening ntawm daim tawv nqaij
  • hloov ntawm daim tawv nqaij
  • mob hauv siab los yog nruj
  • txias
  • hnoos los yog hoarseness
  • tso zis tsaus
  • raws plab
  • kiv taub hau
  • ua npaws
  • kev xav ntawm nkees lossis qaug zog
  • mob taub hau
  • khaus khaus, daim tawv nqaij ua pob
  • pob qij txha los yog mob leeg
  • cov quav daj
  • poob qab los noj mov
  • sab nraub qaum lossis sab mob
  • xeev siab
  • mob, rhiab, los yog o ntawm ko taw lossis ceg
  • mob los yog tso zis nyuaj
  • tawv nqaij tawv
  • liab ntawm daim tawv nqaij, feem ntau nrog ib tug liab doog chaw
  • liab, khaus qhov muag
  • mob caj pas
  • mob, rwj, los yog pob dawb nyob rau hauv lub qhov ncauj los yog ntawm daim di ncauj
  • mob plab
  • o lossis mob qog
  • ua tsis taus pa
  • tsis kaj siab ua tsis taus pa tsw
  • txawv txav los ntshav los yog bruising
  • ntuav cov ntshav
  • qhov muag daj lossis tawv nqaij

Qhov xwm txheej tsis paub

  • Mob nraub qaum, ceg, lossis mob plab
  • cov pos hniav los ntshav
  • dig muag lossis tsis pom kev hloov
  • mob plab
  • ntshav nyob rau hauv cov zis los yog cov quav
  • xiav-xim daim di ncauj, ntiv tes, los yog xib teg
  • khaus, khaus, khaus, ua tsis taus pa , mob, prickling, 'pins thiab koob', los yog tingling kev xav
  • hlawv ntawm lub ntsej muag lossis qhov ncauj
  • huab tso zis
  • tsis meej pem
  • cem quav
  • txuas ntxiv ringing los yog buzzing los yog lwm yam unexplained suab nyob rau hauv pob ntseg
  • tawg ntawm daim tawv nqaij
  • txo zaus los yog tso zis ntau
  • nyuaj nrog nqos
  • ua tsis taus pa
  • lub cev o
  • kev xav tsis xis nyob los yog mob
  • plaub hau poob
  • tsis hnov ​​lus
  • khaus khaus
  • nce nqhis dej
  • plab zom mov
  • lub plawv dhia tsis xwm yeem
  • loj, tiaj tus, xiav, lossis purplish thaj ua rau ntawm daim tawv nqaij
  • loj, ua pob zoo li o ntawm lub ntsej muag, daim tawv muag, daim di ncauj, tus nplaig, caj pas, tes, ceg, ko taw, lossis cov kab mob sib deev
  • poob ntawm tshav kub ntawm lub cev
  • mob nqaij los yog pob qij txha
  • ntshav ntswg
  • tsis muaj peev xwm dhau zis
  • loog lossis tingling ntawm tes, ko taw, lossis daim di ncauj
  • mob lossis kub hnyiab thaum tso zis
  • pinpoint liab me ntsis ntawm daim tawv nqaij
  • puffiness los yog o ntawm daim tawv muag los yog ib ncig ntawm lub qhov muag, ntsej muag, daim di ncauj, los yog tus nplaig
  • tsa cov pob liab liab ntawm daim tawv nqaij, pob tw, ceg, lossis pob taws
  • liab ntawm qhov dawb ntawm qhov muag
  • liab, o, los yog mob ntawm tus nplaig
  • qaug dab peg
  • mob ntawm cov leeg
  • txha caj dab los yog rov qab
  • plab tenderness
  • o ntawm lub ntsej muag, tes, ob txhais ceg, thiab ko taw
  • tsis khov, tshee, lossis lwm yam teeb meem nrog kev tswj cov leeg lossis kev sib koom tes
  • qaug zog ntawm txhais tes lossis ko taw
  • qaug zog los yog hnyav ntawm ob txhais ceg
  • hnyav nce lossis poob

Kev mob tshwm sim tsis tas yuav tsum tau kho mob tam sim

Qee qhov kev mob tshwm sim ntawm sulfamethoxazole / trimethoprim tuaj yeem tshwm sim uas feem ntau tsis xav tau kev kho mob . Cov kev mob tshwm sim no yuav ploj mus thaum kho raws li koj lub cev hloov kho rau cov tshuaj. Tsis tas li ntawd, koj tus kws kho mob tuaj yeem qhia koj txog txoj hauv kev los tiv thaiv lossis txo qee qhov kev mob tshwm sim.

Tshawb xyuas nrog koj tus kws kho mob yog tias muaj cov kev mob tshwm sim hauv qab no txuas ntxiv los yog thab plaub los yog koj muaj lus nug txog lawv:

Feem ntau

  • Dhau ntawm roj

Qhov xwm txheej tsis paub

  • Kev poob siab
  • kev xav tsis tu ncua ntawm tus kheej lossis ib puag ncig
  • xav tu siab los tsis muaj
  • nce rhiab heev ntawm daim tawv nqaij rau hnub ci
  • tsis muaj kev xav lossis kev xav
  • tsis txaus siab lossis txaus siab
  • ntxhov siab
  • redness los yog lwm yam discoloration ntawm daim tawv nqaij
  • pom, hnov, lossis hnov ​​tej yam uas tsis nyob ntawd
  • kev xav ntawm spinning
  • sunburn hnyav
  • teeb meem tsom
  • teeb meem pw tsaug zog
  • tsis quav ntsej
  • poob phaus

Rau Cov Kws Kho Mob

Siv rau sulfamethoxazole / trimethoprim: tshuaj intravenous, kev ncua ntawm qhov ncauj, ntsiav tshuaj ntawm qhov ncauj

General

Cov kev mob tshwm sim feem ntau yog mob plab hnyuv (xws li xeev siab, ntuav, anorexia) thiab kev tsis haum ntawm daim tawv nqaij (piv txwv li, ua pob liab vog, urticaria ).

Cov teebmeem cuam tshuam nrog Pneumocystis jirovecii mob ntsws o kev tswj hwm muaj xws li kev mob hnyav heev, ua pob liab liab, pyrexia, neutropenia , thrombocytopenia , nce siab enzymes , hyperkalemia , hyponatremia thiab rhabdomyolysis; cov teebmeem no tsis tshua muaj heev.

Txawm hais tias tsis tshua muaj, kev tuag cuam tshuam nrog kev siv sulfonamide tau tshwm sim vim muaj kev cuam tshuam loj heev, suav nrog Stevens-Johnson Syndrome , tshuaj lom epidermal necrolysis fulminant hepatic necrosis, agranulocytosis , aplastic anemia , lwm cov ntshav dyscrasia, thiab ua pa hypersensitivity.[ Ref ]

Metabolic

Feem ntau (10% lossis ntau dua): Hyperkalemia

Zaus tsis qhia : Anorexia, hypoglycemia , hyponatremia, tsis qab los noj mov

Postmarketing qhia : Metabolic acidosis [ Ref ]

Hypoglycemia tau tshaj tawm hauv cov neeg mob siv sulfonamides .[ Ref ]

plab hnyuv

Feem ntau (1% mus rau 10%): xeev siab, raws plab

Tsis tshua muaj (0.1% rau 1%): ntuav

Zaus tsis qhia : Glossitis, stomatitis pseudomembranous enterocolitis, pancreatitis , emesis , mob plab , pseudomembranous colitis , Clostridium difficile-associated raws plab , cem quav, mob qhov ncauj[ Ref ]

Lub paj hlwb

Aseptic meningitis tau rov qab sai sai thaum cov tshuaj no raug tso tseg tab sis rov tshwm sim nyob rau hauv ob peb kis thaum rov raug cov tshuaj no ua ke los yog trimethoprim ib leeg.

tremor thiab lwm yam neurological tshwm sim (piv txwv li, ataxia, pob taws clonus, apathy) tshwm sim thaum kho nrog cov tshuaj no hauv ntau tus neeg mob AIDS; Txawm hais tias cov txiaj ntsig zoo li no kuj tau cuam tshuam nrog cov txheej txheem kab mob hauv qab, cov tsos mob no tau daws tsis pub dhau 2 mus rau 3 hnub tom qab tso tseg cov tshuaj no.[ Ref ]

Feem ntau (1% mus rau 10%): Mob taub hau

Zaus tsis qhia : Aseptic meningitis, convulsions / qaug dab peg, peripheral neuritis / neuropathy, ataxia, kiv taub hau, vertigo , tinnitus , tshee, lwm yam neurological tshwm sim (piv txwv li, ataxia, pob taws clonus, apathy), qaug zog ua paresthesia, syncope [ Ref ]

Dermatology

Feem ntau (1% mus rau 10%): Ua pob

Zaus tsis qhia Cov pob liab liab liab, erythematous pob, maculopapular pob, morbilliform pob, pruritic pob, urticaria, photosensitivity, pruritus , exfoliative dermatitis, tsau tshuaj eruption, erythema multiforme, Stevens-Johnson syndrome, tshuaj lom epidermal necrolysis, Henoch-Schonlein purpura, tshuaj tiv thaiv nrog eosinophilia thiab cov tsos mob ntawm cov kab mob (DRESS), cov tawv nqaij eruptions, purpura, angioedema Generalized pustular dermatosis, alopecia , ua xua/hypersensitivity vasculitis zoo li Henoch-Schonlein purpura, erythema nodosum, bullous dermatitis[ Ref ]

Lwm yam

Feem ntau (1% mus rau 10%): Fungal / monilial overgrowth

Zaus tsis qhia : Tshuaj kub cev, ua daus no, qaug zog, qaug zog, nce siab tsis zoo hauv alkaline phosphatase, zoo lupus erythematous tshwm sim, moniliasis[ Ref ]

alka seltzer ntxiv ntau npaum qhia

Mob plawv

Zaus tsis qhia : Thrombophlebitis, tsis haum myocarditis, polyarteritis / periarteritis nodosa

Postmarketing qhia : QT prolongation (ua rau ventricular tachycardia thiab torsade de pointes)[ Ref ]

Hematology

Zaus tsis qhia : leukopenia, neutropenia, thrombocytopenia, pob txha pob txha kev nyuaj siab agranulocytosis, aplastic anemia, hemolytic anemia, megaloblastic anemia, methemoglobinemia, hypoprothrombinemia, eosinophilia, hematological toxicity, hemolysis, pancytopenia , granulocytopenia

Postmarketing qhia : thrombocytopenic purpura, idiopathic thrombocytopenic purpura[ Ref ]

Cov mob hnyav ntawm thrombocytopenia uas ua rau tuag taus lossis ua rau muaj kev phom sij rau lub neej tau raug tshaj tawm. Thrombocytopenia feem ntau daws tau nyob rau hauv ib lub lis piam thaum cov tshuaj no raug txiav.

Hemolysis tau tshaj tawm hauv qee cov neeg mob uas tsis muaj qabzib-6-phosphate tsis txaus.[ Ref ]

Mob siab

Zaus tsis qhia : Kab mob siab, cholestatic daj daj , hepatic necrosis, nce serum transaminase, nce bilirubin, hloov pauv hauv siab, nce siab hauv cov ntshav transaminase, jaundice, siab siab enzymes, cuam tshuam hauv daim siab enzymes[ Ref ]

Cov mob cholestatic jaundice thiab hepatic necrosis tau ua rau tuag taus.

Jaundice (feem ntau me me thiab ib ntus) tau tshaj tawm tsis tshua muaj, feem ntau tshwm sim hauv cov neeg mob uas muaj keeb kwm kis kab mob siab.[ Ref ]

Mob siab heev

Zaus tsis qhia : hypersensitivity, allergic ntawm daim tawv nqaij, anaphylaxis , serum mob-zoo li syndrome, generalized kev tsis haum tshuaj , anaphylactic / anaphylactoid cov tshuaj tiv thaiv, cov tshuaj tiv thaiv hnyav heev (xws li cuam tshuam nrog P jirovecii pneumonia), mob ntshav qab zib[ Ref ]

Hauv zos

Zaus tsis qhia : Cov tshuaj tiv thaiv hauv zos, mob, me ntsis / lub zos khaus, o[ Ref ]

Cov tshuaj tiv thaiv hauv zos, qhov mob, thiab khaus me ntsis tau tshaj tawm tsis tu ncua nrog kev tswj hwm IV.[ Ref ]

Musculoskeletal

Zaus tsis qhia mob: arthralgia, myalgia, rhabdomyolysis, systemic lupus erythematosus , leeg tsis muaj zog[ Ref ]

Rhabdomyolysis tau tshaj tawm nrog cov tshuaj no, feem ntau hauv cov neeg mob AIDS.[ Ref ]

Ocular

Zaus tsis qhia : Uveitis , conjunctival thiab scleral txhaj / liab / edema , periorbital edema, corneal nplhaib infiltrates, teeb meem tsis pom kev[ Ref ]

Kev puas siab puas ntsws

Zaus tsis qhia : Kev nyuaj siab/kev puas siab puas ntsws, hnov ​​​​lus, apathy, nervousness, insomnia , psychotic disorder, tsis meej pem xeev, agitation, kev ntxhov siab , tus cwj pwm txawv txawv, npau suav phem [ Ref ]

Lub raum

Nephrotoxicity tau tshaj tawm nyob rau hauv koom nrog cyclosporine .[ Ref ]

Zaus tsis qhia : Lub raum tsis ua hauj lwm / tsis ua hauj lwm, interstitial nephritis, tubulointerstitial nephritis thiab uveitis syndrome, elevated BUN, elevated serum creatinine, tshuaj lom mob nephrosis Lub raum tubular acidosis, nephrotoxicity, hloov lub raum ua haujlwm, nce siab hauv cov ntshav urea, nce siab hauv cov ntshav creatinine, pob zeb tsim, tubular necrosis, aggravation ntawm lub raum kab mob, azotemia, hyperkalemic raum tubular acidosis, overestimations ntawm ib txwm muaj nuj nqis creatinine.[ Ref ]

Cov kab mob genitourinary

Diuresis tau tshaj tawm hauv cov neeg mob siv sulfonamides .[ Ref ]

Zaus tsis qhia : Oliguria, anuria, crystalluria, diuresis, dysuria , hematuria , kev hloov pauv sai, qhov nce siab hauv cov zis protein ntau[ Ref ]

Ua pa

Zaus tsis qhia : Khov, ua tsis taus pa / ua tsis taus pa, pulmonary infiltrates / ntsws infiltration, epistaxis, eosinophilic / allergic alveolitis, hawb pob[ Ref ]

hnoos, dyspnea, thiab ntsws infiltration yog qhov taw qhia ntxov ntawm kev ua pa tsis zoo uas, thaum tsawg heev, tau ua rau tuag taus.[ Ref ]

Cov ntaub ntawv

1. 'Cov ntaub ntawv khoom. Septra (trimethoprim-sulfamethoxazole). Glaxo Wellcome, Kev Tshawb Fawb Daim duab peb sab Park, NC.

2. Cerner Multum, Inc. 'Australian Product Information.' O 0

3. Cerner Multum, Inc. 'UK Summary of Product Characteristics.' O 0

4. 'Cov ntaub ntawv khoom. Sulfamethoxazole-Trimethoprim (sulfamethoxazole-trimethoprim). SICOR Pharmaceuticals Inc, Irvine, CA.

Cov ntaub ntawv ntxiv

Nco ntsoov sab laj nrog koj tus kws kho mob kom paub tseeb tias cov ntaub ntawv uas tshwm sim hauv nplooj ntawv no siv tau rau koj tus kheej.

Qee qhov kev mob tshwm sim yuav tsis qhia. Koj tuaj yeem qhia lawv mus rau lub vev xaib FDA .