Trileptal Side Effects

Lub npe dav: tshuaj oxcarbazepine

Nco tseg: Cov ntaub ntawv no muaj cov ntaub ntawv cuam tshuam txog oxcarbazepine. Qee cov ntaub ntawv noj tshuaj uas tau teev tseg rau ntawm nplooj ntawv no yuav tsis siv rau lub npe Trileptal.



Hauv Summary

Cov kev phiv tshwm sim ntawm Trileptal muaj xws li: kiv taub hau. Saib hauv qab no kom paub cov npe ntawm cov teebmeem tsis zoo.

Rau Cov Neeg Siv Khoom

Siv rau tshuaj oxcarbazepine : qhov ncauj ncua kev kawm ntawv, qhov ncauj ntsiav tshuaj, qhov ncauj ntsiav tshuaj ncua kev tso tawm

Kev mob tshwm sim yuav tsum tau mus kho mob tam sim

Nrog rau nws cov teebmeem xav tau, oxcarbazepine (cov khoom muaj nyob hauv Trileptal ) tej zaum yuav ua rau tej yam tsis xav tau. Txawm hais tias tsis yog tag nrho cov kev mob tshwm sim no tuaj yeem tshwm sim, yog tias lawv tshwm sim lawv yuav xav tau kev kho mob.

Nrog koj tus kws kho mob tham tam sim ntawd Yog tias ib qho ntawm cov kev mob tshwm sim hauv qab no tshwm sim thaum noj oxcarbazepine:

Feem ntau

  • Hloov hauv kev pom
  • hloov hauv kev taug kev lossis sib npaug
  • clumsiness los yog unstadiness
  • hnoos
  • quaj
  • kiv taub hau
  • pom ob npaug
  • cuav kev zoo siab
  • kev xav tsis tu ncua ntawm tus kheej lossis ib puag ncig
  • ua npaws
  • puas hlwb kev nyuaj siab
  • kev xav ntawm spinning
  • txham
  • mob caj pas
  • tswj tsis tau rov qab los yog dov qhov muag txav

Tsawg dua

  • Kev ntxhov siab
  • kev nyuaj siab
  • ntshav los yog huab tso zis
  • qhov muag tsis pom kev
  • nqaij tawv
  • tsis meej pem txog tus kheej, qhov chaw, thiab lub sijhawm
  • txo tso zis
  • nyuaj nrog tsom qhov muag
  • kiv taub hau, faintness, los yog lightheadedness thaum sawv tam sim ntawd los ntawm ib qho chaw pw los yog zaum
  • ceev los yog lub plawv dhia tsis xwm yeem
  • nquag ntog
  • nquag tso zis
  • mob taub hau
  • hnov lus
  • nce nqhis dej
  • tsis nco qab
  • nco poob
  • cov leeg mob
  • mob lossis kub hnyiab thaum tso zis
  • mob los yog rhiab nyob ib ncig ntawm lub qhov muag los yog cheekbones
  • teeb meem nrog kev sib koom tes
  • tshee los yog tshee ntawm caj npab, ceg, tes, thiab ko taw
  • qaug dab peg
  • daim tawv nqaij ua pob
  • khaus los yog kua ntswg
  • nruj hauv siab
  • teeb meem nrog kev taug kev
  • ua tsis taus pa
  • kev xav txawv txawv
  • nkees nkees lossis qaug zog

Tsis tshua muaj

  • Kev ntxhov siab
  • los ntshav los yog kab mob ntawm daim di ncauj
  • kub hnyiab hauv siab los yog plab
  • mob hauv siab
  • txias
  • khaus khaus los yog cov welts , khaus
  • chim siab
  • mob sib koom
  • loj, o zoo li o ntawm lub ntsej muag, daim tawv muag, daim di ncauj, tus nplaig, caj pas, tes, ceg, taw, lossis qhov chaw mos
  • mob nqaij lossis qaug zog
  • liab doog ntawm daim tawv nqaij
  • qhov quav los ntshav
  • redness, blistering, tev, los yog loosening ntawm daim tawv nqaij
  • kev ntxhov siab
  • mob, rwj, los yog pob dawb nyob rau hauv lub qhov ncauj los yog ntawm daim di ncauj
  • plab chim
  • o ntawm ob txhais ceg
  • qog o

Qhov xwm txheej tsis paub

  • Dub, tarry quav
  • mob plab
  • cem quav
  • tso zis tsaus
  • txo qhov siab
  • txo kev paub lossis kev ua haujlwm
  • nyuaj nqos
  • tawv nqaij qhuav thiab plaub hau
  • ua tsis taus pa
  • xav txias
  • plaub hau poob
  • kev ua phem
  • plab zom mov
  • poob qab los noj mov
  • tsis nco qab
  • nqaij tawv los yog twitching
  • xeev siab
  • mob hauv nraub qaum, tav, caj npab, lossis ob txhais ceg
  • mob hauv plab, sab, lossis plab, tejzaum nws tawg mus rau sab nraub qaum
  • pounding, lub plawv dhia qeeb
  • puffiness los yog o ntawm daim tawv muag los yog ib ncig ntawm lub qhov muag, ntsej muag, daim di ncauj, los yog tus nplaig
  • hnyav nce sai
  • tsaug zog heev
  • o ntawm lub ntsej muag, pob taws, lossis ob txhais tes
  • o, mob, lossis mob qog nqaij hlav hauv caj dab, caj dab, lossis puab tais
  • los ntshav los yog bruising txawv txawv
  • qaug zog txawv txav, dullness, los yog xav tias sluggishness
  • ntuav
  • hnyav nce
  • qhov muag daj lossis tawv nqaij

Kev mob tshwm sim tsis tas yuav tsum tau kho mob tam sim

Qee qhov kev mob tshwm sim ntawm oxcarbazepine tuaj yeem tshwm sim uas feem ntau tsis xav tau kev kho mob . Cov kev mob tshwm sim no yuav ploj mus thaum kho raws li koj lub cev hloov kho rau cov tshuaj. Tsis tas li ntawd, koj tus kws kho mob yuav tuaj yeem qhia koj txog txoj hauv kev los tiv thaiv lossis txo qee qhov kev mob tshwm sim.

Tshawb xyuas nrog koj tus kws kho mob yog tias muaj cov kev mob tshwm sim hauv qab no txuas ntxiv los yog thab plaub los yog koj muaj lus nug txog lawv:

Feem ntau

clotrimazole cream siv rau dab tsi
  • Kev kub nyhiab hauv siab lossis lub plab
  • pw tsaug zog los yog pw tsaug zog txawv txawv
  • mob plab

Tsawg dua

  • Pob txuv
  • mob nraub qaum
  • belching
  • ntshav qhov ntswg
  • hloov hauv koj lub siab nyiam
  • raws plab
  • nyuaj hais lus
  • dryness ntawm lub qhov ncauj
  • kev xav ntawm sov thiab liab ntawm lub ntsej muag, caj dab, caj npab, thiab qee zaum hauv siab
  • mob plawv
  • nce hws
  • tso zis ntau ntxiv
  • khaus ntawm qhov chaw mos
  • teeb meem pw tsaug zog

Rau Cov Kws Kho Mob

Siv rau oxcarbazepine: qhov ncauj raug tshem tawm, ntsiav tshuaj ntawm qhov ncauj, ntsiav tshuaj qhov ncauj ncua kev tso tawm

General

Feem ntau pom cov kev mob tshwm sim yog kiv taub hau, somnolence, diplopia, qaug zog, xeev siab, ntuav, ataxia, tsis pom kev, mob plab , tshee, dyspepsia , abnormal gait, mob taub hau, kev tsis sib haum xeeb , thiab asthenia. Hauv kev sim tshuaj hauv cov menyuam yaus hnub nyoog 1 hlis txog 4 xyoos, qhov tshwm sim feem ntau tshaj tawm yog somnolence.

Cov kev mob tshwm sim feem ntau cuam tshuam nrog kev txiav tawm ntawm oxcarbazepine (cov khoom muaj nyob hauv Trileptal) suav nrog kiv taub hau, ntuav, xeev siab, diplopia, thiab tsaug zog.[ Ref ]

Lub paj hlwb

Feem ntau (10% los yog ntau tshaj): gait txawv txav, ataxia, kiv taub hau, mob taub hau, nystagmus, somnolence, tshee

Feem ntau (1% mus rau 10%): Kev sib koom ua ke txawv txav, txawv txav EEG, amnesia, ataxia, kev tsis sib haum xeeb, kev ua tsis taus pa hnyav, kev raug mob hauv lub cev tsis tau teev tseg, dysmetria, gait cuam tshuam, hypoesthesia, impaired concentration, involuntary leeg contractions, hais lus tsis meej, saj perversion

Zaus tsis qhia : Aura, kev nyuaj siab theem ntawm kev nco qab, dystonia , extrapyramidal teeb meem, hemiplegia, hyperreflexia, hyperkinesia, hyporeflexia, hypokinesia, hypotonia, migraine mob hypertonia, neuralgia oculogyric ntsoog, tuag tes tuag taw, syncope , tinnitus [ Ref ]

tshuaj tua kab mob zoo tshaj plaws yog dab tsi

Tus qauv ntawm qaug dab peg tom qab oxcarbazepine txiav tawm qhia txog qhov tshwm sim rov zoo dua li qhov kev poob ntawm kev kho mob.[ Ref ]

Kev puas siab puas ntsws

Kev soj ntsuam sib xyaw ua ke ntawm 199 qhov kev sim tshuaj placebo-tswj ntawm 11 cov tshuaj sib txawv ntawm cov tshuaj tiv thaiv kab mob ua kom ntev li ib nrab ntawm 12 lub lis piam pom tau tias cov neeg mob tau txais cov tshuaj tiv thaiv kab mob muaj kwv yees li ob npaug ntawm kev pheej hmoo ntawm kev tua tus kheej lossis kev xav (0.43%) piv rau cov neeg mob tau txais cov placebo (0.22%). Qhov kev pheej hmoo siab ntawm tus cwj pwm tua tus kheej thiab kev xav tua tus kheej tau pom thaum ntxov li ib lub lis piam tom qab pib cov tshuaj tiv thaiv kab mob thiab txuas ntxiv mus txog 24 lub lis piam.[ Ref ]

Feem ntau (1% txog 10%): Kev xav txawv txav, ntxhov siab, ntxhov siab, tsis meej pem, tsis meej pem, kev nyuaj siab, insomnia , kev xav lability, nervousness

Zaus tsis qhia Cov tshuaj tiv thaiv hnyav, ntxhov siab, ntxhov siab, aphasia, delirium, delusion, dysphonia, euphoria, hysteria, manic tshuaj tiv thaiv, kev ntxhov siab , parniria, cwm pwm tsis meej, psychosis, stupor, suicidal cwj pwm thiab ideation[ Ref ]

Dermatology

Feem ntau (1% mus rau 10%): Pob txuv, alopecia , bruising, nce tawm hws, purpura, pob

Tsis tshua muaj (0.1% mus rau 1%): Urticaria

Tsawg heev (tsawg dua 0.01%): Angioedema , erythema multiforme, Stevens-Johnson Syndrome , tshuaj lom epidermal necrolysis ( Lyell's Syndrome )

Zaus tsis qhia : Tiv tauj dermatitis , eczema , erythematous ua pob liab vog, lub ntsej muag pob, folliculitis, qhov chaw mos pruritus , tshav kub pob, maculopapular pob, photosensitivity tshuaj tiv thaiv, psoriasis purpura, tawv nqaij txheej txheem, vitiligo

Postmarketing qhia : Mob generalized exanthematous pustulosis (AGEP)[ Ref ]

Cov neeg mob nrog Human Leukocyte Antigen (HLA) allele B * 1502 lossis HLA-A * 3101 yuav muaj kev pheej hmoo ntau ntxiv rau Stevens-Johnson syndrome (SJS) thiab toxic epidermal necrolysis (TEN). Lub xub ntiag ntawm HLA-A * 3101 allele kuj tseem tuaj yeem ua rau muaj kev pheej hmoo rau cov tshuaj ua pob liab liab nrog eosinophilia (DRESS), los yog tsis tshua muaj mob hnyav generalized exanthematous pustulosis (AGEP) thiab maculopapular pob.

Tsis tshua muaj mob ntawm angioedema tau tshaj tawm hauv cov neeg mob tom qab noj thawj zaug lossis tom qab koob tshuaj oxcarbazepine.[ Ref ]

Mob siab heev

Feem ntau (1% mus rau 10%): Allergy

Tsawg heev (tsawg dua 0.01%): Hypersensitivity (nrog rau ntau lub cev tsis muaj zog), cov tshuaj tiv thaiv anaphylactic

Zaus tsis qhia : Tshuaj pob khaus nrog eosinophilia thiab cov tsos mob ntawm lub cev (DRESS)[ Ref ]

Tsis tshua muaj mob ntawm anaphylaxis tau tshaj tawm hauv cov neeg mob tom qab noj thawj zaug lossis tom qab koob tshuaj oxcarbazepine.

Multi-organ hypersensitivity feem ntau tshwm sim los ntawm cov tsos mob thiab cov tsos mob xws li txawv txav kuaj lub siab ua haujlwm , tawm pob, thiab kub taub hau. Lwm yam kabmob lossis cov tsos mob uas yuav cuam tshuam nrog rau cov ntshav thiab lymphatic system (xws li, lymphadenopathy eosinophilia, leukopenia, splenomegaly), daim siab (xws li, txawv txav kuaj lub siab ua haujlwm , kab mob siab), cov leeg thiab pob qij txha (xws li, pob qij txha o, myalgia, arthralgia), paj hlwb (xws li, hepatic encephalopathy ), raum (piv txwv li, proteinuria, interstitial nephritis, raum tsis ua haujlwm), thiab ntsws (xws li, ua tsis taus pa , pulmonary edema , mob hawb pob , bronchospasm, kab mob ntsws interstitial).[ Ref ]

plab hnyuv

Feem ntau (10% lossis ntau dua): mob plab, xeev siab, ntuav

Feem ntau (1% mus rau 10%): cem quav, raws plab, dyspepsia, qhov ncauj qhuav, mob plab , mob plab , mob hniav , mob plab plab

Zaus tsis qhia : mob biliary, ntshav hauv cov quav, cholelithiasis , mob plab , duodenal rwj , dysphagia kab mob enteritis, eructation , esophagitis , flatulence gastric ulcer, gingival los ntshav, pos hniav hyperplasia, hematemesis, hemorrhoids txoj cai hypochondrium mob, retching, sialoadenitis, stomatitis , ulcerative stomatitis, kev kho hniav ntawm qhov ncauj

Postmarketing qhia : Pancreatitis [ Ref ]

Mob plawv

Feem ntau (1% mus rau 10%): mob hauv siab, generalized edema , mob khaub thuas, hypotension , ceg edema

tonsillectomy hauv cov neeg laus cov lus qhia rov qab

Tsawg heev (tsawg dua 0.01%): Arrhythmia , atrioventricular block, kub siab

Zaus tsis qhia : Bradycardia , mob plawv tsis ua haujlwm, cerebral hemorrhage palpitations, postural hypotension, mob hauv siab precordial, tachycardia [ Ref ]

Cov kab mob genitourinary

Feem ntau (1% mus rau 10%): Kab mob tso zis, micturition zaus, vaginitis

Zaus tsis qhia : Txo / nce libido, dysuria , poj niam txoj kev yug me nyuam, intermenstrual los ntshav, leukorrhea, menorrhagia , micturition zaus, polyuria, priapism , mob raum, mob urinary tract[ Ref ]

Hematology

Feem ntau (1% mus rau 10%): Lymphadenopathy

Tsis tshua muaj (0.1% mus rau 1%): Leukopenia

Tsawg heev (tsawg dua 0.01%): Agranulocytosis , aplastic anemia , pob txha pob txha depression, neutropenia , pancytopenia , thrombocytopenia [ Ref ]

Mob siab

Tsis tshua muaj (0.1% mus rau 1%): nce ntshav alkaline phosphatase, nce siab enzymes

Tsawg heev (tsawg dua 0.01%): Kab mob siab

Zaus tsis qhia : Nce GGT, nce serum transaminase[ Ref ]

Immunologic

Feem ntau (1% mus rau 10%): Kab mob, kis kab mob

Zaus tsis qhia : Systemic lupus erythematosus [ Ref ]

Metabolic

Hyponatremia cuam ​​tshuam nrog cov cim qhia thiab cov tsos mob xws li qaug dab peg, tsis meej pem, kev nyuaj siab ntawm kev nco qab, encephalopathy , pom kev tsis pom kev, ntuav, xeev siab, thiab folic acid deficiency tau raug tshaj tawm tsis tshua muaj.[ Ref ]

Feem ntau (1% mus rau 10%): Anorexia, hyponatremia, nqhis dej, hnyav nce

Zaus tsis qhia : Txo qis hauv T4 nrog qhov tsis pom tseeb qhov tseem ceeb, hyperglycemia, hypocalcemia , hypoglycemia , hypokalemia , hypothyroidism, nce qab los noj mov, tetany, yuag poob

Postmarketing qhia : Nce amylase, nce lipase[ Ref ]

Musculoskeletal

Feem ntau (1% mus rau 10%): Mob nraub qaum, leeg tsis muaj zog, sprains thiab hom

Zaus tsis qhia : Cov txheej txheem musculoskeletal

Postmarketing qhia : Txo cov pob txha ntxhia pob txha, osteopenia , osteoporosis thiab pob txha (kev kho mus sij hawm ntev)[ Ref ]

Ocular

Feem ntau (10% los yog ntau tshaj): Cov kev pab txawv txav, tsis pom kev, diplopia

Feem ntau (1% mus rau 10%): qhov muag tsis pom kev, qhov muag tsis pom kev / cuam tshuam

Zaus tsis qhia : Cataract conjunctival hemorrhage, qhov muag edema, hemianopia, mydriasis, photophobia, scotoma, xerophthalmia[ Ref ]

Lwm yam

Feem ntau (10% lossis ntau dua): Kev qaug zog, vertigo

Feem ntau (1% mus rau 10%): Asthenia, tsis kam noj tshuaj, mob pob ntseg, pob ntseg tsis tau teev tseg, poob qis tsis tau teev tseg, tsis txaus ntseeg, kub taub hau

Zaus tsis qhia : Xav qaug cawv, malaise, otitis sab nraud , ptosis, rigors[ Ref ]

Lub raum

Zaus tsis qhia : Lub raum Calculus[ Ref ]

Ua pa

Feem ntau (10% lossis ntau dua): Upper respiratory tract infection

Feem ntau (1% mus rau 10%): bronchitis, mob hauv siab, hnoos, epistaxis, nasopharyngitis, mob ntsws o , pharyngitis rhinitis, sinusitis

Zaus tsis qhia : hawb pob, dyspnea, hiccup, laryngismus, pleurisy[ Ref ]

Cov ntaub ntawv

1. 'Cov ntaub ntawv khoom. Trileptal (oxcarbazepine)' Novartis Pharmaceuticals, East Hanover, NJ.

2. Friis ML, Kristensen O, Boas J, Dalby M, Deth SH, Gram L, Mikkelsen M, Pedersen B, Sabers A, Worm-Petersen J, et al 'Cov kev paub kho mob nrog 947 tus neeg mob epileptic tawm hauv kev kho oxcarbazepine.' Acta Neurol Scand 87 (1993): 224-7

3. Cerner Multum, Inc. 'UK Summary of Product Characteristics.' O 0

4. 'Cov ntaub ntawv khoom. Oxtellar XR (OXcarbazepine). Supernus Pharmaceuticals Inc, Rockville, MD.

5. Van Amelsvoort T, Bakshi R, Devaux CB, Schwabe S 'Hyponatremia txuam nrog carbamazepine thiab oxcarbazepine therapy: kev tshuaj xyuas.' Epilepsia 35 (1994): 181-8

Kuv yuav coj benadryl nrog lexapro

6. Cerner Multum, Inc. 'Australian Product Information.' O 0

7. Azar NJ, Wright AT, Wang L, Song Y, Abou-Khalil BW 'Generalized tonic-clonic qaug dab peg tom qab mob oxcarbazepine tshem tawm.' Neurology 70(22 Pt 2) (2008): 2187-8

8. Ryan M, Adams AG, Larive LL 'Hyponatremia thiab leukopenia cuam tshuam nrog oxcarbazepine tom qab kho carbamazepine.' Am J Health Syst Pharm 58 (2001): 1637-9

9. Woster P, Carrazana EJ 'Oxcarbazepine thiab hyponatremia.' Am J Health Syst Pharm 59 (2002): 467

Cov ntaub ntawv ntxiv

Nco ntsoov sab laj nrog koj tus kws kho mob kom paub meej tias cov ntaub ntawv uas tshwm sim hauv nplooj ntawv no siv tau rau koj tus kheej.

Qee qhov kev mob tshwm sim yuav tsis qhia. Koj tuaj yeem qhia lawv mus rau lub FDA .